chloride

ChEBI · EMBL-EBI ↗ · Källdatum saknas · Källans villkor

A halide anion formed when chlorine picks up an electron to form an an anion.

LiChao; ZhaiYi; JiangHeming; LiSiqi; LiuPengxiang; GaoLongcheng; JiangLei · Bioinspired light-driven chloride pump with helical porphyrin channels ↗ · 27 jan. 2024 · Källans villkor

Membrane-embedded protein ion pumps and channels control the physiological activities by regulating the transport of ions across the cell membrane1–3.

LiChao; ZhaiYi; JiangHeming; LiSiqi; LiuPengxiang; GaoLongcheng; JiangLei · Bioinspired light-driven chloride pump with helical porphyrin channels ↗ · 27 jan. 2024 · Källans villkor

Up to now, none of the artificial ion channels have achieved light-driven chloride ion pumps like the HR channel. Learning from the structure and mechanism of the HR channel, the artificial light-driven chloride pump should at least meet two basic requirements: the photo-receptor and the specific chloride selective site. Titanium dioxide (TiO2)17,18, porphyrin19,20, spiropyran21,22, graphitic carbon nitride23, and azobenzene24,25 are the most common materials used to construct the light-responsive channels for the effect of photo-induced electro or photo-isomerization. Due to the lack of chloride selective site, none of these channels exhibit the specific chloride selectivity as the HR channel does. To mimic the photo-driven chloride ion pump, light-responsive groups with specific chloride ion transport sites should be introduced into the nanochannel. Derived from the Schiff base structure of the HR channel, the porphyrin with the nitrogen-containing conjugated structure is supposed to be an ideal structure to achieve light-responsive chloride ion transport. Aligning the porphyrin into the channel and utilizing the cavity for chloride transport could achieve the light-driven chloride ion pump.

LiChao; ZhaiYi; JiangHeming; LiSiqi; LiuPengxiang; GaoLongcheng; JiangLei · Bioinspired light-driven chloride pump with helical porphyrin channels ↗ · 27 jan. 2024 · Källans villkor

Here, we apply the fabrication strategy of biological HR channels to align a small content of porphyrin into the helical channels under the synergetic interaction, exhibiting a high diffusion current density of 0.68 mA·cm−2 with the light-driven chloride selective transport (Fig. 1b). The helical porphyrin channel is self-assembled by a porphyrin-cored block copolymer (p-BCP) and quantitively doping its porphyrin initiator (TPP) to repair the inevitable defects along the channels. As a result, the porphyrin d-spacing decreases, resulting in the decrement of ion transport resistance. The helical channel exhibits excellent Cl− selectivity toward cations and anions like F−, Br−, H2PO4−, and HCO3−. Under the driven force with the light radiation, the Cl− could undergo the directional migration even without the external potential or concentration gradient, converting solar energy into electronic energy. The power density of the light-driven ion pump reaches 56.0 mW·m−2 under the symmetric concentration gradient. Furthermore, Cl− could migrate against a 3-fold concentration gradient under light irradiation. The design strategy for the light-responsive channel with the least functional groups and the mechanism of light-driven Cl− transport could highlight the prospect in the fields of the fabrication of bioinspired smart systems and the high-efficiency harvesting for solar energy.