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Publikationer i urvalet

39 träffar

Bibliografisk träff 2020-09-16

Bis-Quinolinium Cyclophane Blockers of SK Potassium Channels Are Antagonists of M3 Muscarinic Acetylcholine Receptors.

Bugay V, Wallace DJ, Wang B, Salinas I, Chapparo AP, Smith HR, Dube PH, Brooks EG, Berg KA, Brenner R.

Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2020.552211

Bibliografisk träff 2020-08-01

The Small Conductance Calcium-Activated Potassium Channel Inhibitors NS8593 and UCL1684 Prevent the Development of Atrial Fibrillation Through Atrial-Selective Inhibition of Sodium Channel Activity.

Burashnikov A, Barajas-Martinez H, Hu D, Robinson VM, Grunnet M, Antzelevitch C.

J Cardiovasc Pharmacol · comparative study; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1097/fjc.0000000000000855

Bibliografisk träff 2019-01-29

Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion.

Dickerson MT, Dadi PK, Altman MK, Verlage KR, Thorson AS, Jordan KL, Vierra NC, Amarnath G, Jacobson DA.

Am J Physiol Endocrinol Metab · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1152/ajpendo.00342.2018

Bibliografisk träff 2018-04-06

Small-conductance Ca2+-activated K+ channel activation deteriorates hypoxic ventricular arrhythmias via CaMKII in cardiac hypertrophy.

Tenma T, Mitsuyama H, Watanabe M, Kakutani N, Otsuka Y, Mizukami K, Kamada R, Takahashi M, Takada S, Sabe H, Tsutsui H, Yokoshiki H.

Am J Physiol Heart Circ Physiol · research support, non-u.s. gov't; journal article · DOI 10.1152/ajpheart.00636.2017

Bibliografisk träff 2018-01-09

Acute epileptiform activity induced by gabazine involves proteasomal rather than lysosomal degradation of KCa2.2 channels.

Müller S, Guli X, Hey J, Einsle A, Pfanz D, Sudmann V, Kirschstein T, Köhling R.

Neurobiol Dis · research support, non-u.s. gov't; journal article · DOI 10.1016/j.nbd.2018.01.005

Bibliografisk träff 2017-11-09

Rapid versus slow ascending vasodilatation: intercellular conduction versus flow-mediated signalling with tetanic versus rhythmic muscle contractions.

Sinkler SY, Segal SS.

J Physiol · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1113/jp275186

Bibliografisk träff 2016-01-26

Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats.

Mokhtar SS, Vanhoutte PM, Leung SW, Suppian R, Yusof MI, Rasool AH.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2016.01.013

Bibliografisk träff 2015-03-27

Kaempferol enhances endothelium-dependent relaxation in the porcine coronary artery through activation of large-conductance Ca(2+) -activated K(+) channels.

Xu YC, Leung SW, Leung GP, Man RY.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bph.13108

Bibliografisk träff 2015-01-23

TRPV4 and K(Ca) ion channels functionally couple as osmosensors in the paraventricular nucleus.

Feetham CH, Nunn N, Lewis R, Dart C, Barrett-Jolley R.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bph.13023

Bibliografisk träff 2014-10-24

Vanillin and vanillin analogs relax porcine coronary and basilar arteries by inhibiting L-type Ca2+ channels.

Raffai G, Khang G, Vanhoutte PM.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1124/jpet.114.217935

Bibliografisk träff 2014-05-01

Angiotensin-(1-7) augments endothelium-dependent relaxations of porcine coronary arteries to bradykinin by inhibiting angiotensin-converting enzyme 1.

Raffai G, Khang G, Vanhoutte PM.

J Cardiovasc Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1097/fjc.0000000000000069

Bibliografisk träff 2014-04-03

Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats.

Toniolo EF, Maique ET, Ferreira WA, Heimann AS, Ferro ES, Ramos-Ortolaza DL, Miller L, Devi LA, Dale CS.

Peptides · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.peptides.2014.03.016

Bibliografisk träff 2013-08-01

Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes.

Chennupati R, Lamers WH, Koehler SE, De Mey JG.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bph.12175

Bibliografisk träff 2013-03-06

Further studies on bis-charged tetraazacyclophanes as potent inhibitors of small conductance Ca(2+)-activated K+ channels.

Yang D, Arifhodzic L, Ganellin CR, Jenkinson DH.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.02.029

Bibliografisk träff 2013-01-30

Proarrhythmic effect of blocking the small conductance calcium activated potassium channel in isolated canine left atrium.

Hsueh CH, Chang PC, Hsieh YC, Reher T, Chen PS, Lin SF.

Heart Rhythm · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.hrthm.2013.01.033

Bibliografisk träff 2012-10-19

Ventricular tachyarrhythmias in rats with acute myocardial infarction involves activation of small-conductance Ca2+-activated K+ channels.

Gui L, Bao Z, Jia Y, Qin X, Cheng ZJ, Zhu J, Chen QH.

Am J Physiol Heart Circ Physiol · research support, non-u.s. gov't; journal article · DOI 10.1152/ajpheart.00820.2011

Bibliografisk träff 2012-06-01

Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.

Chubanov V, Mederos y Schnitzler M, Meißner M, Schäfer S, Abstiens K, Hofmann T, Gudermann T.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1476-5381.2012.01855.x

Bibliografisk träff 2012-02-13

Endoplasmic reticulum potassium-hydrogen exchanger and small conductance calcium-activated potassium channel activities are essential for ER calcium uptake in neurons and cardiomyocytes.

Kuum M, Veksler V, Liiv J, Ventura-Clapier R, Kaasik A.

J Cell Sci · research support, non-u.s. gov't; journal article · DOI 10.1242/jcs.090126

Bibliografisk träff 2011-06-10

Cross-reactivity of ryanodine receptors with plasma membrane ion channel modulators.

Neumann JT, Copello JA.

Mol Pharmacol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/mol.111.071167

Bibliografisk träff 2011-06-01

The duration of pacing-induced atrial fibrillation is reduced in vivo by inhibition of small conductance Ca(2+)-activated K(+) channels.

Skibsbye L, Diness JG, Sørensen US, Hansen RS, Grunnet M.

J Cardiovasc Pharmacol · comparative study; validation study; journal article · DOI 10.1097/fjc.0b013e318217943d

Bibliografisk träff 2011-04-18

Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition.

Diness JG, Skibsbye L, Jespersen T, Bartels ED, Sørensen US, Hansen RS, Grunnet M.

Hypertension · research support, non-u.s. gov't; journal article · DOI 10.1161/hypertensionaha.111.170613

Bibliografisk träff 2011-02-04

Secretoneurin facilitates endothelium-dependent relaxations in porcine coronary arteries.

Chan CK, Vanhoutte PM.

Am J Physiol Heart Circ Physiol · research support, non-u.s. gov't; journal article · DOI 10.1152/ajpheart.00519.2010

Bibliografisk träff 2009-12-29

Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries.

Hilgers RH, Janssen GM, Fazzi GE, De Mey JG.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1124/jpet.109.161448

Bibliografisk träff 2009-10-09

A key role for Na+/K+-ATPase in the endothelium-dependent oscillatory activity of mouse small mesenteric arteries.

Giachini FR, Carneiro FS, Lima VV, Carneiro ZN, Brands MW, Webb RC, Tostes RC.

Braz J Med Biol Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1590/s0100-879x2009005000033

Bibliografisk träff 2009-07-31

Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive rats.

Giachini FR, Carneiro FS, Lima VV, Carneiro ZN, Dorrance A, Webb RC, Tostes RC.

Transl Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.trsl.2009.07.003

Bibliografisk träff 2009-07-23

Inhibition of vascular calcium-gated chloride currents by blockers of KCa1.1, but not by modulators of KCa2.1 or KCa2.3 channels.

Sones WR, Leblanc N, Greenwood IA.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/j.1476-5381.2009.00332.x

Bibliografisk träff 2008-09-09

SK channel blockade promotes burst firing in dorsal raphe serotonergic neurons.

Rouchet N, Waroux O, Lamy C, Massotte L, Scuvée-Moreau J, Liégeois JF, Seutin V.

Eur J Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1460-9568.2008.06430.x

Bibliografisk träff 2008-06-23

Hypertension and the absence of EDHF-mediated responses favour endothelium-dependent contractions in renal arteries of the rat.

Michel FS, Man GS, Man RY, Vanhoutte PM.

Br J Pharmacol · other; research support, non-u.s. gov't; journal article · DOI 10.1038/bjp.2008.256

Bibliografisk träff 2007-01-05

Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension.

Hilgers RH, Webb RC.

Am J Physiol Heart Circ Physiol · journal article · DOI 10.1152/ajpheart.00949.2006

Bibliografisk träff 2005-10-01

Pharmacological properties and functional role of Kslow current in mouse pancreatic beta-cells: SK channels contribute to Kslow tail current and modulate insulin secretion.

Zhang M, Houamed K, Kupershmidt S, Roden D, Satin LS.

J Gen Physiol · research support, u.s. gov't, p.h.s.; research-article; journal article; research support, n.i.h., extramural · DOI 10.1085/jgp.200509312

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Publikationer i urvalet

Bis-Quinolinium Cyclophane Blockers of SK Potassium Channels Are Antagonists of M3 Muscarinic Acetylcholine Receptors.

The Small Conductance Calcium-Activated Potassium Channel Inhibitors NS8593 and UCL1684 Prevent the Development of Atrial Fibrillation Through Atrial-Selective Inhibition of Sodium Channel Activity.

Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion.

Small-conductance Ca<sup>2+</sup>-activated K<sup>+</sup> channel activation deteriorates hypoxic ventricular arrhythmias via CaMKII in cardiac hypertrophy.

Acute epileptiform activity induced by gabazine involves proteasomal rather than lysosomal degradation of K<sub>Ca</sub>2.2 channels.

Rapid versus slow ascending vasodilatation: intercellular conduction versus flow-mediated signalling with tetanic versus rhythmic muscle contractions.

Reduced nitric oxide-mediated relaxation and endothelial nitric oxide synthase expression in the tail arteries of streptozotocin-induced diabetic rats.

Kaempferol enhances endothelium-dependent relaxation in the porcine coronary artery through activation of large-conductance Ca(2+) -activated K(+) channels.

TRPV4 and K(Ca) ion channels functionally couple as osmosensors in the paraventricular nucleus.

Vanillin and vanillin analogs relax porcine coronary and basilar arteries by inhibiting L-type Ca2+ channels.

Angiotensin-(1-7) augments endothelium-dependent relaxations of porcine coronary arteries to bradykinin by inhibiting angiotensin-converting enzyme 1.

Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats.

Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes.

Further studies on bis-charged tetraazacyclophanes as potent inhibitors of small conductance Ca(2+)-activated K+ channels.

Proarrhythmic effect of blocking the small conductance calcium activated potassium channel in isolated canine left atrium.

Ventricular tachyarrhythmias in rats with acute myocardial infarction involves activation of small-conductance Ca2+-activated K+ channels.

Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.

Endoplasmic reticulum potassium-hydrogen exchanger and small conductance calcium-activated potassium channel activities are essential for ER calcium uptake in neurons and cardiomyocytes.

Cross-reactivity of ryanodine receptors with plasma membrane ion channel modulators.

The duration of pacing-induced atrial fibrillation is reduced in vivo by inhibition of small conductance Ca(2+)-activated K(+) channels.

Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition.

Secretoneurin facilitates endothelium-dependent relaxations in porcine coronary arteries.

Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries.

A key role for Na+/K+-ATPase in the endothelium-dependent oscillatory activity of mouse small mesenteric arteries.

Upregulation of intermediate calcium-activated potassium channels counterbalance the impaired endothelium-dependent vasodilation in stroke-prone spontaneously hypertensive rats.

Inhibition of vascular calcium-gated chloride currents by blockers of KCa1.1, but not by modulators of KCa2.1 or KCa2.3 channels.

SK channel blockade promotes burst firing in dorsal raphe serotonergic neurons.

Hypertension and the absence of EDHF-mediated responses favour endothelium-dependent contractions in renal arteries of the rat.

Reduced expression of SKCa and IKCa channel proteins in rat small mesenteric arteries during angiotensin II-induced hypertension.

Pharmacological properties and functional role of Kslow current in mouse pancreatic beta-cells: SK channels contribute to Kslow tail current and modulate insulin secretion.