DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.
Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
50 träffarIdentification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase.
Shea TA, Burburan PJ, Matubia VN, Ramcharan SS, Rosario I, Parkin DW, Stockman BJ.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2014.01.014A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Morgan RE, van Staden CJ, Chen Y, Kalyanaraman N, Kalanzi J, Dunn RT, Afshari CA, Hamadeh HK.
Toxicol Sci · journal article · DOI 10.1093/toxsci/kft176Structure-based identification of OATP1B1/3 inhibitors.
De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.
Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.112.084152Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
Wolman AT, Gionfriddo MR, Heindel GA, Mukhija P, Witkowski S, Bommareddy A, Vanwert AL.
Drug Metab Dispos · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1124/dmd.112.049569Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.
PLoS Comput Biol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1371/journal.pcbi.1002310Oral availability of cefadroxil depends on ABCC3 and ABCC4.
de Waart DR, van de Wetering K, Kunne C, Duijst S, Paulusma CC, Oude Elferink RP.
Drug Metab Dispos · journal article · DOI 10.1124/dmd.111.041731Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.
Pedretti A, De Luca L, Marconi C, Regazzoni L, Aldini G, Vistoli G.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2011.06.027blaROB-1 presence on pB1000 in Haemophilus influenzae is widespread, and variable cefaclor resistance is associated with altered penicillin-binding proteins.
Tristram SG, Littlejohn R, Bradbury RS.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00263-10The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics.
Collins B, Curtis N, Cotter PD, Hill C, Ross RP.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00503-10Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007).
Pérez-Trallero E, Martín-Herrero JE, Mazón A, García-Delafuente C, Robles P, Iriarte V, Dal-Ré R, García-de-Lomas J, Spanish Surveillance Group for Respiratory Pathogens.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01548-09Membrane transporters in drug development.
International Transporter Consortium, Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L.
Nat Rev Drug Discov · research-article; review; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1038/nrd3028Synthesis and antimicrobial activity of cholic acid hydrazone analogues.
Rasras AJ, Al-Tel TH, Al-Aboudi AF, Al-Qawasmeh RA.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2010.02.006Haemophilus influenzae clinical isolates with plasmid pB1000 bearing blaROB-1: fitness cost and interspecies dissemination.
San Millan A, Garcia-Cobos S, Escudero JA, Hidalgo L, Gutierrez B, Carrilero L, Campos J, Gonzalez-Zorn B.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01489-09GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.
Kotsakis SD, Papagiannitsis CC, Tzelepi E, Legakis NJ, Miriagou V, Tzouvelekis LS.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.01561-09Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.
Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326kAntimicrobial resistance in Haemophilus influenzae respiratory tract isolates in Korea: results of a nationwide acute respiratory infections surveillance.
Bae S, Lee J, Lee J, Kim E, Lee S, Yu J, Kang Y.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00966-09Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
Miguet L, Zervosen A, Gerards T, Pasha FA, Luxen A, Distèche-Nguyen M, Thomas A.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm900625qMultiresistance in Pasteurella multocida is mediated by coexistence of small plasmids.
San Millan A, Escudero JA, Gutierrez B, Hidalgo L, Garcia N, Llagostera M, Dominguez L, Gonzalez-Zorn B.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01522-08Extended-spectrum properties of CMY-30, a Val211Gly mutant of CMY-2 cephalosporinase.
Kotsakis SD, Papagiannitsis CC, Tzelepi E, Tzouvelekis LS, Miriagou V.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00219-09Soft-tissue penetration of ceftobiprole in healthy volunteers determined by in vivo microdialysis.
Barbour A, Schmidt S, Sabarinath SN, Grant M, Seubert C, Skee D, Murthy B, Derendorf H.
Antimicrob Agents Chemother · clinical trial; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.01409-08Relative strengths of the class 1 integron promoter hybrid 2 and the combinations of strong and hybrid 1 with an active p2 promoter.
Papagiannitsis CC, Tzouvelekis LS, Miriagou V.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00912-08Novel chimeric beta-lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta-lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime.
Nagano Y, Nagano N, Wachino J, Ishikawa K, Arakawa Y.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00227-08Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers.
Sevillano D, Giménez MJ, Cercenado E, Cafini F, Gené A, Alou L, Marco F, Martínez-Martínez L, Coronel P, Aguilar L.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00402-08Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800656vLow beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method.
García-Cobos S, Campos J, Román F, Carrera C, Pérez-Vázquez M, Aracil B, Oteo J.
Antimicrob Agents Chemother · comparative study; research support, non-u.s. gov't; research-article; evaluation study; journal article · DOI 10.1128/aac.00214-08Synthesis and antibacterial activity of some new 2,3-dimethoxy-3-hydroxy-2-(1-phenyl-3-aryl-4-pyrazolyl)chromanones.
Prakash O, Kumar R, Sehrawat R.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2008.03.028Hologram QSAR model for the prediction of human oral bioavailability.
Moda TL, Montanari CA, Andricopulo AD.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.08.060Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli.
Papagiannitsis CC, Tzouvelekis LS, Tzelepi E, Miriagou V.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00389-07Can the Etest correctly determine the MICs of beta-lactam and cephalosporin antibiotics for beta-lactamase-negative ampicillin-resistant Haemophilus influenzae?
Billal DS, Hotomi M, Yamanaka N.
Antimicrob Agents Chemother · letter · DOI 10.1128/aac.00190-07