Auraptene: a natural biologically active compound with multiple targets.
Genovese S, Epifano F.
Curr Drug Targets · review; journal article · DOI 10.2174/138945011794815248 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
62 träffarPotential benefits of supplementation with auraptene in cystic fibrosis.
Sahebkar A.
Clin Nutr · letter · DOI 10.1016/j.clnu.2010.08.004Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors.
de Medina P, Genovese S, Paillasse MR, Mazaheri M, Caze-Subra S, Bystricky K, Curini M, Silvente-Poirot S, Epifano F, Poirot M.
Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.110.065250Effects of citrus auraptene (7-geranyloxycoumarin) on hepatic lipid metabolism in vitro and in vivo.
Nagao K, Yamano N, Shirouchi B, Inoue N, Murakami S, Sasaki T, Yanagita T.
J Agric Food Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jf1020329Suppression of CD74 expression and Helicobacter pylori adhesion by auraptene targeting serum starvation-activated ERK1/2 in NCI-N87 gastric carcinoma cells.
Sekiguchi H, Irie K, Murakami A.
Biosci Biotechnol Biochem · research support, non-u.s. gov't; journal article · DOI 10.1271/bbb.90910Colorectal cancer chemoprevention by 2 beta-cyclodextrin inclusion compounds of auraptene and 4'-geranyloxyferulic acid.
Tanaka T, de Azevedo MB, Durán N, Alderete JB, Epifano F, Genovese S, Tanaka M, Tanaka T, Curini M.
Int J Cancer · research support, non-u.s. gov't; journal article · DOI 10.1002/ijc.24833Auraptene from Ferula szowitsiana protects human peripheral lymphocytes against oxidative stress.
Soltani F, Mosaffa F, Iranshahi M, Karimi G, Malekaneh M, Haghighi F, Behravan J.
Phytother Res · research support, non-u.s. gov't; journal article · DOI 10.1002/ptr.2874Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats.
Krishnan P, Yan KJ, Windler D, Tubbs J, Grand R, Li BD, Aldaz CM, McLarty J, Kleiner-Hancock HE.
BMC Cancer · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1186/1471-2407-9-259Metabolism and absorption of auraptene (7-geranyloxylcoumarin) in male SD rats: comparison with 7-ethoxycoumarin.
Kuki W, Hosotani K, Ohigashi H, Murakami A.
Nutr Cancer · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1080/01635580701745327Auraptene, a citrus fruit compound, regulates gene expression as a PPARalpha agonist in HepG2 hepatocytes.
Takahashi N, Takahashi N, Kang MS, Kuroyanagi K, Goto T, Hirai S, Ohyama K, Lee JY, Yu R, Yano M, Sasaki T, Murakami S, Kawada T.
Biofactors · research support, non-u.s. gov't; journal article · DOI 10.1002/biof.5520330103Citrus auraptene acts as an agonist for PPARs and enhances adiponectin production and MCP-1 reduction in 3T3-L1 adipocytes.
Kuroyanagi K, Kang MS, Goto T, Hirai S, Ohyama K, Kusudo T, Yu R, Yano M, Sasaki T, Takahashi N, Takahashi N, Kawada T.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2007.11.119Apoptogenic activity of auraptene of Zanthoxylum schinifolium toward human acute leukemia Jurkat T cells is associated with ER stress-mediated caspase-8 activation that stimulates mitochondria-dependent or -independent caspase cascade.
Jun DY, Kim JS, Park HS, Han CR, Fang Z, Woo MH, Rhee IK, Kim YH.
Carcinogenesis · research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/bgm028Protective effects of citrus nobiletin and auraptene in transgenic rats developing adenocarcinoma of the prostate (TRAP) and human prostate carcinoma cells.
Tang M, Ogawa K, Asamoto M, Hokaiwado N, Seeni A, Suzuki S, Takahashi S, Tanaka T, Ichikawa K, Shirai T.
Cancer Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1349-7006.2007.00417.xCitrus auraptene suppresses azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db mice.
Hayashi K, Suzuki R, Miyamoto S, Shin-Ichiroh Y, Kohno H, Sugie S, Takashima S, Tanaka T.
Nutr Cancer · research support, non-u.s. gov't; journal article · DOI 10.1080/01635580701308216Citrus auraptene reduces Helicobacter pylori colonization of glandular stomach lesions in Mongolian gerbils.
Takeda K, Utsunomiya H, Kakiuchi S, Okuno Y, Oda K, Inada K, Tsutsumi Y, Tanaka T, Kakudo K.
J Oleo Sci · research support, non-u.s. gov't; journal article · DOI 10.5650/jos.56.253Auraptene decreases the activity of matrix metalloproteinases in dextran sulfate sodium-induced ulcerative colitis in ICR mice.
Kawabata K, Murakami A, Ohigashi H.
Biosci Biotechnol Biochem · research support, non-u.s. gov't; journal article · DOI 10.1271/bbb.60393Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism.
Kawabata K, Murakami A, Ohigashi H.
FEBS Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.febslet.2006.08.072Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice.
Kohno H, Suzuki R, Curini M, Epifano F, Maltese F, Gonzales SP, Tanaka T.
Int J Cancer · research support, non-u.s. gov't; journal article · DOI 10.1002/ijc.21719Zingiberaceous and citrus constituents, 1'-acetoxychavicol acetate, zerumbone, auraptene, and nobiletin, suppress lipopolysaccharide-induced cyclooxygenase-2 expression in RAW264.7 murine macrophages through different modes of action.
Murakami A, Shigemori T, Ohigashi H.
J Nutr · research support, non-u.s. gov't; journal article · DOI 10.1093/jn/135.12.2987sSuppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats.
Hara A, Sakata K, Yamada Y, Kuno T, Kitaori N, Oyama T, Hirose Y, Murakami A, Tanaka T, Mori H.
Oncol Rep · research support, non-u.s. gov't; journal article · DOI 10.3892/or.14.2.345Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis.
Sakata K, Hara A, Hirose Y, Yamada Y, Kuno T, Katayama M, Yoshida K, Zheng Q, Murakami A, Ohigashi H, Ikemoto K, Koshimizu K, Tanaka T, Mori H.
Oncology · research support, non-u.s. gov't; journal article · DOI 10.1159/000078001Suppression by citrus auraptene of phorbol ester-and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation.
Murakami A, Nakamura Y, Tanaka T, Kawabata K, Takahashi D, Koshimizu K, Ohigashi H.
Carcinogenesis · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/21.10.1843Suppressing effects of dietary supplementation of the organoselenium 1,4-phenylenebis(methylene)selenocyanate and the Citrus antioxidant auraptene on lung metastasis of melanoma cells in mice.
Tanaka T, Kohno H, Murakami M, Kagami S, El-Bayoumy K.
Cancer Res · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal articleEvaluation of auraptene content in citrus fruits and their products.
Ogawa K, Kawasaki A, Yoshida T, Nesumi H, Nakano M, Ikoma Y, Yano M.
J Agric Food Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jf9905525Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of auraptene.
Kawabata K, Tanaka T, Yamamoto T, Hara A, Murakami A, Koshimizu K, Ohigashi H, Stoner GD, Mori H.
J Exp Clin Cancer Res · research support, non-u.s. gov't; journal articleIn vitro absorption and metabolism of a citrus chemopreventive agent, auraptene, and its modifying effects on xenobiotic enzyme activities in mouse livers.
Murakami A, Wada K, Ueda N, Sasaki K, Haga M, Kuki W, Takahashi Y, Yonei H, Koshimizu K, Ohigashi H.
Nutr Cancer · research support, non-u.s. gov't; journal article · DOI 10.1207/s15327914nc3602_8Immunomodulatory action of citrus auraptene on macrophage functions and cytokine production of lymphocytes in female BALB/c mice.
Tanaka T, Sugiura H, Inaba R, Nishikawa A, Murakami A, Koshimizu K, Ohigashi H.
Carcinogenesis · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/20.8.1471Citrus auraptene exerts dose-dependent chemopreventive activity in rat large bowel tumorigenesis: the inhibition correlates with suppression of cell proliferation and lipid peroxidation and with induction of phase II drug-metabolizing enzymes.
Tanaka T, Kawabata K, Kakumoto M, Hara A, Murakami A, Kuki W, Takahashi Y, Yonei H, Maeda M, Ota T, Odashima S, Yamane T, Koshimizu K, Ohigashi H.
Cancer Res · research support, non-u.s. gov't; journal articleChemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by citrus auraptene in rats.
Tanaka T, Kawabata K, Kakumoto M, Matsunaga K, Mori H, Murakami A, Kuki W, Takahashi Y, Yonei H, Satoh K, Hara A, Maeda M, Ota T, Odashima S, Koshimizu K, Ohigashi H.
Carcinogenesis · research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/19.3.425Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats.
Tanaka T, Kawabata K, Kakumoto M, Makita H, Hara A, Mori H, Satoh K, Hara A, Murakami A, Kuki W, Takahashi Y, Yonei H, Koshimizu K, Ohigashi H.
Carcinogenesis · research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/18.11.2155