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Publikationer i urvalet

51 träffar

Bibliografisk träff 2016-12-27

The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo.

Jostes S, Nettersheim D, Fellermeyer M, Schneider S, Hafezi F, Honecker F, Schumacher V, Geyer M, Kristiansen G, Schorle H.

J Cell Mol Med · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/jcmm.13059

Bibliografisk träff 2016-11-23

BET bromodomain inhibitor (JQ1) and tumor angiogenesis.

Bid HK, Kerk S.

Oncoscience · editorial · DOI 10.18632/oncoscience.326

Bibliografisk träff 2016-11-18

AMPK-ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells.

Jang JE, Eom JI, Jeung HK, Cheong JW, Lee JY, Kim JS, Min YH.

Clin Cancer Res · journal article · DOI 10.1158/1078-0432.ccr-16-1903

Bibliografisk träff 2016-11-01

MYCL is a target of a BET bromodomain inhibitor, JQ1, on growth suppression efficacy in small cell lung cancer cells.

Kato F, Fiorentino FP, Alibés A, Perucho M, Sánchez-Céspedes M, Kohno T, Yokota J.

Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.12671

Bibliografisk träff 2016-10-06

CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells.

Lian H, Li D, Zhou Y, Landesman-Bollag E, Zhang G, Anderson NM, Tang KC, Roderick JE, Kelliher MA, Seldin DC, Fu H, Feng H.

Haematologica · letter · DOI 10.3324/haematol.2016.154013

Tillbakadragen publikation 2016-10-01

JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer.

Qiu H, Li J, Clark LH, Jackson AL, Zhang L, Guo H, Kilgore JE, Gehrig PA, Zhou C, Bae-Jump VL.

Oncotarget · retracted publication; research-article; journal article · DOI 10.18632/oncotarget.11631

Bibliografisk träff 2016-09-01

Stromal remodeling by the BET bromodomain inhibitor JQ1 suppresses the progression of human pancreatic cancer.

Yamamoto K, Tateishi K, Kudo Y, Hoshikawa M, Tanaka M, Nakatsuka T, Fujiwara H, Miyabayashi K, Takahashi R, Tanaka Y, Ijichi H, Nakai Y, Isayama H, Morishita Y, Aoki T, Sakamoto Y, Hasegawa K, Kokudo N, Fukayama M, Koike K.

Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.11129

Bibliografisk träff 2016-08-24

JQ1, a small molecule inhibitor of BRD4, suppresses cell growth and invasion in oral squamous cell carcinoma.

Wang L, Wu X, Huang P, Lv Z, Qi Y, Wei X, Yang P, Zhang F.

Oncol Rep · journal article · DOI 10.3892/or.2016.5037

Bibliografisk träff 2016-08-18

Bromodomain and extra-terminal protein mimic JQ1 decreases inflammation in human vascular endothelial cells: Implications for pulmonary arterial hypertension.

Mumby S, Gambaryan N, Meng C, Perros F, Humbert M, Wort SJ, Adcock IM.

Respirology · research-article; journal article · DOI 10.1111/resp.12872

Bibliografisk träff 2016-08-01

[Effect of BRD4 Inhibitor JQ1 on Proliferation Inhibition and Apotosis Induction in Jurkat Cells].

Sun XX, Ma LM, Wang T.

Zhongguo Shi Yan Xue Ye Xue Za Zhi · journal article · DOI 10.7534/j.issn.1009-2137.2016.04.011

Bibliografisk träff 2016-07-20

Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model.

Zhu X, Enomoto K, Zhao L, Zhu YJ, Willingham MC, Meltzer P, Qi J, Cheng SY.

Clin Cancer Res · research-article; journal article · DOI 10.1158/1078-0432.ccr-16-0914

Bibliografisk träff 2016-06-24

Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.

Donato E, Croci O, Sabò A, Muller H, Morelli MJ, Pelizzola M, Campaner S.

Leukemia · research-article; journal article · DOI 10.1038/leu.2016.182

Bibliografisk träff 2016-06-13

The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.

da Motta LL, Ledaki I, Purshouse K, Haider S, De Bastiani MA, Baban D, Morotti M, Steers G, Wigfield S, Bridges E, Li JL, Knapp S, Ebner D, Klamt F, Harris AL, McIntyre A.

Oncogene · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/onc.2016.184

Bibliografisk träff 2016-02-23

The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma.

Bid HK, Phelps DA, Xaio L, Guttridge DC, Lin J, London C, Baker LH, Mo X, Houghton PJ.

Mol Cancer Ther · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1158/1535-7163.mct-15-0567

Bibliografisk träff 2016-02-01

BET protein inhibitor JQ1 inhibits growth and modulates WNT signaling in mesenchymal stem cells.

Alghamdi S, Khan I, Beeravolu N, McKee C, Thibodeau B, Wilson G, Chaudhry GR.

Stem Cell Res Ther · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s13287-016-0278-3

Bibliografisk träff 2016-01-05

The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects.

Shahbazi J, Liu PY, Atmadibrata B, Bradner JE, Marshall GM, Lock RB, Liu T.

Clin Cancer Res · journal article · DOI 10.1158/1078-0432.ccr-15-1666

Bibliografisk träff 2016-01-01

Open Access Could Transform Drug Discovery: A Case Study of JQ1.

Arshad Z, Smith J, Roberts M, Lee WH, Davies B, Bure K, Hollander GA, Dopson S, Bountra C, Brindley D.

Expert Opin Drug Discov · review; journal article · DOI 10.1517/17460441.2016.1144587

Bibliografisk träff 2016-01-01

The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease.

Magistri M, Velmeshev D, Makhmutova M, Patel P, Sartor GC, Volmar CH, Wahlestedt C, Faghihi MA.

Curr Alzheimer Res · research-article; journal article; research support, n.i.h., extramural · DOI 10.2174/1567205013666160427101832

Bibliografisk träff 2015-07-23

NSCLC Driven by DDR2 Mutation Is Sensitive to Dasatinib and JQ1 Combination Therapy.

Xu C, Buczkowski KA, Zhang Y, Asahina H, Beauchamp EM, Terai H, Li YY, Meyerson M, Wong KK, Hammerman PS.

Mol Cancer Ther · research-article; journal article; research support, n.i.h., extramural · DOI 10.1158/1535-7163.mct-15-0077

Bibliografisk träff 2013-08-01

BET bromodomains mediate transcriptional pause release in heart failure.

Anand P, Brown JD, Lin CY, Qi J, Zhang R, Artero PC, Alaiti MA, Bullard J, Alazem K, Margulies KB, Cappola TP, Lemieux M, Plutzky J, Bradner JE, Haldar SM.

Cell · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.cell.2013.07.013

Bibliografisk träff 2010-09-24

Selective inhibition of BET bromodomains.

Filippakopoulos P, Qi J, Picaud S, Shen Y, Smith WB, Fedorov O, Morse EM, Keates T, Hickman TT, Felletar I, Philpott M, Munro S, McKeown MR, Wang Y, Christie AL, West N, Cameron MJ, Schwartz B, Heightman TD, La Thangue N, French CA, Wiest O, Kung AL, Knapp S, Bradner JE.

Nature · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/nature09504