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Publikationer i urvalet

50 träffar

Bibliografisk träff 2008-12-24

Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.

Isik S, Kockar F, Aydin M, Arslan O, Guler OO, Innocenti A, Scozzafava A, Supuran CT.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2008.12.035

Bibliografisk träff 2007-08-25

Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.

Nishimori I, Minakuchi T, Onishi S, Vullo D, Cecchi A, Scozzafava A, Supuran CT.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.08.037

Bibliografisk träff 2007-04-25

Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.

Nishimori I, Minakuchi T, Kohsaki T, Onishi S, Takeuchi H, Vullo D, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2007.04.063

Bibliografisk träff 2007-01-01

Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.

Nishimori I, Minakuchi T, Onishi S, Vullo D, Scozzafava A, Supuran CT.

J Med Chem · journal article · DOI 10.1021/jm0612057

Bibliografisk träff 2006-12-03

Anti-mycobacterial activity of a bis-sulfonamide.

Wilkinson BL, Bornaghi LF, Wright AD, Houston TA, Poulsen SA.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2006.11.079

Bibliografisk träff 2006-03-01

Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.

Nishimori I, Minakuchi T, Morimoto K, Sano S, Onishi S, Takeuchi H, Vullo D, Scozzafava A, Supuran CT.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0512600

Bibliografisk träff 2006-02-03

Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.

Nishimori I, Vullo D, Minakuchi T, Morimoto K, Onishi S, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2006.01.044

Bibliografisk träff 2005-12-01

Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.

Nishimori I, Vullo D, Innocenti A, Scozzafava A, Mastrolorenzo A, Supuran CT.

J Med Chem · comparative study; journal article · DOI 10.1021/jm050483n

Bibliografisk träff 2005-10-06

Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II.

Poulsen SA, Bornaghi LF, Healy PC.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2005.08.113

Bibliografisk träff 2005-09-01

Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.

Nishimori I, Vullo D, Innocenti A, Scozzafava A, Mastrolorenzo A, Supuran CT.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2005.06.055

Bibliografisk träff 2005-03-01

Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating hydrazino moieties.

Winum JY, Dogné JM, Casini A, de Leval X, Montero JL, Scozzafava A, Vullo D, Innocenti A, Supuran CT.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0494826

Bibliografisk träff 2005-02-01

Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?

Vullo D, Innocenti A, Nishimori I, Pastorek J, Scozzafava A, Pastoreková S, Supuran CT.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2004.12.053

Bibliografisk träff 2005-02-01

Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.

Vullo D, Voipio J, Innocenti A, Rivera C, Ranki H, Scozzafava A, Kaila K, Supuran CT.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2004.12.052

Bibliografisk träff 2004-11-01

Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives.

Innocenti A, Antel J, Wurl M, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2004.07.085

Bibliografisk träff 2004-06-01

Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.

Jaiswal M, Khadikar PV, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2004.03.099

Bibliografisk träff 2003-08-01

Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one?

Casini A, Abbate F, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(03)00508-0

Bibliografisk träff 2003-03-01

Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

Vullo D, Franchi M, Gallori E, Pastorek J, Scozzafava A, Pastorekova S, Supuran CT.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/s0960-894x(03)00091-x

Bibliografisk träff 1997-12-01

Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design.

Chand P, Babu YS, Bantia S, Chu N, Cole LB, Kotian PL, Laver WG, Montgomery JA, Pathak VP, Petty SL, Shrout DP, Walsh DA, Walsh GM.

J Med Chem · journal article · DOI 10.1021/jm970479e

Bibliografisk träff 1992-09-01

Energy aspects of oil/water partition leading to the novel hydrophobic parameters for the analysis of quantitative structure-activity relationships.

Da YZ, Ito K, Fujiwara H.

J Med Chem · journal article · DOI 10.1021/jm00096a014

Bibliografisk träff 1986-03-01

Thiopurine methyltransferase: structure-activity relationships for benzoic acid inhibitors and thiophenol substrates.

Ames MM, Selassie CD, Woodson LC, Van Loon JA, Hansch C, Weinshilboum RM.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00153a009