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Publikationer i urvalet

50 träffar

Bibliografisk träff 2010-09-01

Synthesis, stereochemical separation, and biological evaluation of selective inhibitors of human MAO-B: 1-(4-arylthiazol-2-yl)-2-(3-methylcyclohexylidene)hydrazines.

Chimenti F, Secci D, Bolasco A, Chimenti P, Granese A, Carradori S, Yáñez M, Orallo F, Sanna ML, Gallinella B, Cirilli R.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm100120s

Bibliografisk träff 2010-07-17

Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase.

Maccioni E, Alcaro S, Orallo F, Cardia MC, Distinto S, Costa G, Yanez M, Sanna ML, Vigo S, Meleddu R, Secci D.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2010.07.009

Bibliografisk träff 2010-07-08

New halogenated 3-phenylcoumarins as potent and selective MAO-B inhibitors.

Matos MJ, Viña D, Janeiro P, Borges F, Santana L, Uriarte E.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.07.013

Bibliografisk träff 2010-07-01

Developing structure-activity relationships for the prediction of hepatotoxicity.

Greene N, Fisk L, Naven RT, Note RR, Patel ML, Pelletier DJ.

Chem Res Toxicol · journal article · DOI 10.1021/tx1000865

Bibliografisk träff 2010-06-09

Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors.

Chimenti F, Bolasco A, Secci D, Chimenti P, Granese A, Carradori S, Yáñez M, Orallo F, Ortuso F, Alcaro S.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.06.007

Bibliografisk träff 2010-06-01

Synthesis, semipreparative HPLC separation, biological evaluation, and 3D-QSAR of hydrazothiazole derivatives as human monoamine oxidase B inhibitors.

Chimenti F, Secci D, Bolasco A, Chimenti P, Granese A, Carradori S, Maccioni E, Cardia MC, Yáñez M, Orallo F, Alcaro S, Ortuso F, Cirilli R, Ferretti R, Distinto S, Kirchmair J, Langer T.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.05.070

Bibliografisk träff 2010-03-27

Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.

Alcaro S, Gaspar A, Ortuso F, Milhazes N, Orallo F, Uriarte E, Yáñez M, Borges F.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.03.081

Bibliografisk träff 2010-01-04

A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.

Chimenti F, Fioravanti R, Bolasco A, Chimenti P, Secci D, Rossi F, Yáñez M, Orallo F, Ortuso F, Alcaro S, Cirilli R, Ferretti R, Sanna ML.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2009.12.029

Bibliografisk träff 2010-01-04

Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors.

Shi L, Yang Y, Li ZL, Zhu ZW, Liu CH, Zhu HL.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2009.12.065

Bibliografisk träff 2010-01-01

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k

Bibliografisk träff 2009-11-06

Synthesis and inhibitory activity against human monoamine oxidase of N1-thiocarbamoyl-3,5-di(hetero)aryl-4,5-dihydro-(1H)-pyrazole derivatives.

Chimenti F, Carradori S, Secci D, Bolasco A, Bizzarri B, Chimenti P, Granese A, Yáñez M, Orallo F.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2009.11.003

Bibliografisk träff 2009-07-10

Synthesis and evaluation of 6-methyl-3-phenylcoumarins as potent and selective MAO-B inhibitors.

Matos MJ, Viña D, Picciau C, Orallo F, Santana L, Uriarte E.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2009.07.039

Bibliografisk träff 2009-05-01

Chalcones: a valid scaffold for monoamine oxidases inhibitors.

Chimenti F, Fioravanti R, Bolasco A, Chimenti P, Secci D, Rossi F, Yáñez M, Orallo F, Ortuso F, Alcaro S.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm801590u

Bibliografisk träff 2009-04-24

A new series of 3-phenylcoumarins as potent and selective MAO-B inhibitors.

Matos MJ, Viña D, Quezada E, Picciau C, Delogu G, Orallo F, Santana L, Uriarte E.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2009.04.085

Bibliografisk träff 2009-04-01

Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins.

Chimenti F, Secci D, Bolasco A, Chimenti P, Bizzarri B, Granese A, Carradori S, Yáñez M, Orallo F, Ortuso F, Alcaro S.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm801496u

Bibliografisk träff 2008-10-04

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800656v

Bibliografisk träff 2008-07-31

Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl)hydrazones.

Chimenti F, Maccioni E, Secci D, Bolasco A, Chimenti P, Granese A, Carradori S, Alcaro S, Ortuso F, Yáñez M, Orallo F, Cirilli R, Ferretti R, La Torre F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800132g

Bibliografisk träff 2004-08-01

[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].

Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.

Gastroenterol Clin Biol · bibliography; journal article · DOI 10.1016/s0399-8320(04)95062-2

Bibliografisk träff 2003-08-01

Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.

Bruno-Blanch L, Gálvez J, García-Domenech R.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/s0960-894x(03)00535-3

Bibliografisk träff 1976-05-01

Quantitative structure-activity studies on monoamine oxidase inhibitors.

Johnson CL.

J Med Chem · research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/jm00227a005