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Publikationer som ChEBI hänvisar till för piritrexim. Visa hela publikationsregistret

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Publikationer i urvalet

45 träffar

Bibliografisk träff 1996-03-01

Lipophilic antifolates as agents against opportunistic infections. 1. Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations.

Piper JR, Johnson CA, Krauth CA, Carter RL, Hosmer CA, Queener SF, Borotz SE, Pfefferkorn ER.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm950760y

Bibliografisk träff 1996-02-01

High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.

Kuyper LF, Baccanari DP, Jones ML, Hunter RN, Tansik RL, Joyner SS, Boytos CM, Rudolph SK, Knick V, Wilson HR, Caddell JM, Friedman HS, Comley JC, Stables JN.

J Med Chem · comparative study; journal article · DOI 10.1021/jm9505122

Bibliografisk träff 1995-11-01

New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.

Queener SF.

J Med Chem · research support, u.s. gov't, p.h.s.; review; journal article · DOI 10.1021/jm00024a001

Bibliografisk träff 1995-09-01

Selective inhibitors of Candida albicans dihydrofolate reductase: activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines.

Chan JH, Hong JS, Kuyper LF, Baccanari DP, Joyner SS, Tansik RL, Boytos CM, Rudolph SK.

J Med Chem · journal article · DOI 10.1021/jm00018a021

Bibliografisk träff 1995-07-01

2,4-Diaminopyrido[3,2-d]pyrimidine inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii.

Rosowsky A, Forsch RA, Queener SF.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00014a014

Bibliografisk träff 1995-06-01

Novel 2,4-diamino-5-substituted-pyrrolo[2,3-d]pyrimidines as classical and nonclassical antifolate inhibitors of dihydrofolate reductases.

Gangjee A, Mavandadi F, Queener SF, McGuire JJ.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00012a016

Bibliografisk träff 1995-05-01

6-substituted 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines as inhibitors of dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.

Gangjee A, Vasudevan A, Queener SF, Kisliuk RL.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00010a022

Bibliografisk träff 1995-03-01

2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii.

Rosowsky A, Mota CE, Queener SF, Waltham M, Ercikan-Abali E, Bertino JR.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00005a002

Bibliografisk träff 1994-12-01

2,4-Diamino-5-chloroquinazoline analogues of trimetrexate and piritrexim: synthesis and antifolate activity.

Rosowsky A, Mota CE, Wright JE, Queener SF.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00052a011

Bibliografisk träff 1993-10-01

2,4-Diaminothieno[2,3-d]pyrimidine analogues of trimetrexate and piritrexim as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.

Rosowsky A, Mota CE, Wright JE, Freisheim JH, Heusner JJ, McCormack JJ, Queener SF.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00073a009

Bibliografisk träff 1993-10-01

Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents.

Gangjee A, Shi J, Queener SF, Barrows LR, Kisliuk RL.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00074a026

Bibliografisk träff 1990-07-01

Structure-activity relationships of antineoplastic agents in multidrug resistance.

Selassie CD, Hansch C, Khwaja TA.

J Med Chem · journal article · DOI 10.1021/jm00169a014

Bibliografisk träff 1985-12-01

Quantitative structure-activity relationship of antifolate inhibition of bacteria cell cultures resistant and sensitive to methotrexate.

Coats EA, Genther CS, Selassie CD, Strong CD, Hansch C.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00150a026

Bibliografisk träff 1984-03-01

Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.

Selassie CD, Hansch C, Khwaja TA, Dias CB, Pentecost S.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00369a019

Bibliografisk träff 1980-03-01

Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine.

Grivsky EM, Lee S, Sigel CW, Duch DS, Nichol CA.

J Med Chem · journal article · DOI 10.1021/jm00177a025