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Publikationer i urvalet

38 träffar

Bibliografisk träff 2002-10-01

Quantitative structure--activity relations for gammadelta T cell activation by phosphoantigens.

Gossman W, Oldfield E.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/jm020224n

Bibliografisk träff 2002-08-01

Highly potent geminal bisphosphonates. From pamidronate disodium (Aredia) to zoledronic acid (Zometa).

Widler L, Jaeggi KA, Glatt M, Müller K, Bachmann R, Bisping M, Born AR, Cortesi R, Guiglia G, Jeker H, Klein R, Ramseier U, Schmid J, Schreiber G, Seltenmeyer Y, Green JR.

J Med Chem · comparative study; journal article · DOI 10.1021/jm020819i

Bibliografisk träff 2002-07-01

An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs.

Szabo CM, Martin MB, Oldfield E.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm010279+

Bibliografisk träff 2002-07-01

Activity of bisphosphonates against Trypanosoma brucei rhodesiense.

Martin MB, Sanders JM, Kendrick H, de Luca-Fradley K, Lewis JC, Grimley JS, Van Brussel EM, Olsen JR, Meints GA, Burzynska A, Kafarski P, Croft SL, Oldfield E.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm0102809

Bibliografisk träff 2002-05-01

Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents.

Szabo CM, Matsumura Y, Fukura S, Martin MB, Sanders JM, Sengupta S, Cieslak JA, Loftus TC, Lea CR, Lee HJ, Koohang A, Coates RM, Sagami H, Oldfield E.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/jm010412y

Bibliografisk träff 2001-03-01

Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi.

Szajnman SH, Bailey BN, Docampo R, Rodriguez JB.

Bioorg Med Chem Lett · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1016/s0960-894x(01)00057-9

Bibliografisk träff 2001-03-01

Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy.

Martin MB, Grimley JS, Lewis JC, Heath HT, Bailey BN, Kendrick H, Yardley V, Caldera A, Lira R, Urbina JA, Moreno SN, Docampo R, Croft SL, Oldfield E.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm0002578

Bibliografisk träff 2000-10-01

A peptide prodrug approach for improving bisphosphonate oral absorption.

Ezra A, Hoffman A, Breuer E, Alferiev IS, Mönkkönen J, El Hanany-Rozen N, Weiss G, Stepensky D, Gati I, Cohen H, Törmälehto S, Amidon GL, Golomb G.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm980645y