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Publikationer som ChEBI hänvisar till för 5-amino-2-[2-(dimethylamino)ethyl]benzo[de]isoquinoline-1,3-dione. Visa hela publikationsregistret

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Publikationer i urvalet

50 träffar

Bibliografisk träff 2008-11-27

Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studies.

Xie L, Xu Y, Wang F, Liu J, Qian X, Cui J.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2008.11.053

Bibliografisk träff 2007-11-13

Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3-heteroarylmaleimides and heterofused imides.

Ferri N, Beccalli EM, Contini A, Corsini A, Antonino M, Radice T, Pratesi G, Tinelli S, Zunino F, Gelmi ML.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.11.024

Bibliografisk träff 2007-07-26

Highly efficient antitumor agents of heterocycles containing sulfur atom: linear and angular thiazonaphthalimides against human lung cancer cell in vitro.

Qian X, Li Z, Yang Q.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.07.008

Bibliografisk träff 2007-07-21

2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.

Van Quaquebeke E, Mahieu T, Dumont P, Dewelle J, Ribaucour F, Simon G, Sauvage S, Gaussin JF, Tuti J, El Yazidi M, Van Vynckt F, Mijatovic T, Lefranc F, Darro F, Kiss R.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm070315q

Bibliografisk träff 2007-05-17

Molecular design, chemical synthesis, and biological evaluation of '4-1' pentacyclic aryl/heteroaryl-imidazonaphthalimides.

Li F, Cui J, Guo L, Qian X, Ren W, Wang K, Liu F.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.05.032

Bibliografisk träff 2007-02-09

Novel N-oxide of naphthalimides as prodrug leads against hypoxic solid tumor: synthesis and biological evaluation.

Yin H, Xu Y, Qian X, Li Y, Liu J.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2007.02.015

Bibliografisk träff 2005-06-01

Synthesis, antitumor evaluation and DNA photocleaving activity of novel methylthiazonaphthalimides with aminoalkyl side chains.

Li Z, Yang Q, Qian X.

Bioorg Med Chem Lett · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2005.04.012

Bibliografisk träff 2004-10-01

Validation of model of cytochrome P450 2D6: an in silico tool for predicting metabolism and inhibition.

Kemp CA, Flanagan JU, van Eldik AJ, Maréchal JD, Wolf CR, Roberts GC, Paine MJ, Sutcliffe MJ.

J Med Chem · research support, non-u.s. gov't; validation study; journal article · DOI 10.1021/jm049934e

Bibliografisk träff 2004-08-01

[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].

Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.

Gastroenterol Clin Biol · bibliography; journal article · DOI 10.1016/s0399-8320(04)95062-2

Bibliografisk träff 2004-04-01

Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives.

Braña MF, Gradillas A, Gómez A, Acero N, Llinares F, Muñoz-Mingarro D, Abradelo C, Rey-Stolle F, Yuste M, Campos J, Gallo MA, Espinosa A.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0310784

Bibliografisk träff 2004-03-01

New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

Braña MF, Cacho M, García MA, de Pascual-Teresa B, Ramos A, Domínguez MT, Pozuelo JM, Abradelo C, Rey-Stolle MF, Yuste M, Báñez-Coronel M, Lacal JC.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0308850

Bibliografisk träff 2002-12-01

Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

Braña MF, Cacho M, García MA, de Pascual-Teresa B, Ramos A, Acero N, Llinares F, Muñoz-Mingarro D, Abradelo C, Rey-Stolle MF, Yuste M.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm020950q

Bibliografisk träff 2001-12-01

Synthesis of antitumor dendritic imides.

Braña MF, Domínguez G, Sáez B, Romerdahl C, Robinson S, Barlozzari T.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/s0960-894x(01)00618-7

Bibliografisk träff 2000-08-01

Analogues of amonafide and azonafide with novel ring systems.

Sami SM, Dorr RT, Alberts DS, Sólyom AM, Remers WA.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm9905817

Bibliografisk träff 1997-02-01

Chromophore-modified bis-naphthalimides: synthesis and antitumor activity of bis-dibenz[de,h]isoquinoline-1,3-diones.

Braña MF, Castellano JM, Perron D, Maher C, Conlon D, Bousquet PF, George J, Qian XD, Robinson SP.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm960295k

Bibliografisk träff 1996-12-01

2-[2'-(Dimethylamino)ethyl]-1,2-dihydro- 3H-dibenz[de,h]isoquinoline-1,3-diones with substituents at positions 4, 8, 9, 10, and 11. Synthesis, antitumor activity, and quantitative structure-activity relationships.

Sami SM, Dorr RT, Alberts DS, Sólyom AM, Remers WA.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm960623g

Bibliografisk träff 1996-04-01

6- and 7-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H-dibenz[de,h] isoquinoline-1,3-diones: synthesis, nucleophilic displacements, antitumor activity, and quantitative structure-activity relationships.

Sami SM, Dorr RT, Sòlyom AM, Alberts DS, Iyengar BS, Remers WA.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm950742g

Bibliografisk träff 1995-03-01

Amino-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H- dibenz[de,h]isoquinoline-1,3-diones. Synthesis, antitumor activity, and quantitative structure--activity relationship.

Sami SM, Dorr RT, Sólyom AM, Alberts DS, Remers WA.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00006a018

Bibliografisk träff 1993-03-01

2-substituted 1,2-dihydro-3H-dibenz[de,h]isoquinoline-1,3-diones. A new class of antitumor agent.

Sami SM, Dorr RT, Alberts DS, Remers WA.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00058a014

Bibliografisk träff 1985-09-01

N-(Aminoalkyl)imide antineoplastic agents. Synthesis and biological activity.

Zee-Cheng RK, Cheng CC.

J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00147a016