In Silico Investigation of the SARS CoV2 Protease with Thymoquinone, the Major Constituent of Nigella Sativa.
Kadil Y, Mouhcine M, Filali H.
Curr Drug Discov Technol · journal article · DOI 10.2174/1570163817666200712164406 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
23 träffarThymoquinone Inhibits Proliferation and Migration of MDA-MB-231 Triple Negative Breast Cancer Cells by Suppressing Autophagy, Beclin-1 and LC3.
Ünal TD, Hamurcu Z, Delibaşı N, Çınar V, Güler A, Gökçe S, Nurdinov N, Ozpolat B.
Anticancer Agents Med Chem · research support, non-u.s. gov't; journal article · DOI 10.2174/1871520620666200807221047Thymoquinone Suppresses Migration of Human Renal Carcinoma Caki-1 Cells through Inhibition of the PGE<sub>2</sub>-Mediated Activation of the EP2 Receptor Pathway.
Park G, Song NY, Kim DH, Lee SJ, Chun KS.
Biomol Ther (Seoul) · research-article; journal article · DOI 10.4062/biomolther.2020.048Thymoquinone inhibits the proliferation and invasion of esophageal cancer cells by disrupting the AKT/GSK-3β/Wnt signaling pathway via PTEN upregulation.
Ma J, Zhang Y, Deng H, Liu Y, Lei X, He P, Dong W.
Phytother Res · journal article · DOI 10.1002/ptr.6795Stability study of thymoquinone, carvacrol and thymol using HPLC-UV and LC-ESI-MS.
Soliman RM, Abdel Salam RA, Eid BG, Khayyat A, Neamatallah T, Mesbah MK, Hadad GM.
Acta Pharm · validation study; journal article · DOI 10.2478/acph-2020-0028Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta<sub>1-42</sub> infused rat model.
Elibol B, Beker M, Terzioglu-Usak S, Dalli T, Kilic U.
Phytomedicine · journal article · DOI 10.1016/j.phymed.2020.153324Thymoquinone attenuates doxorubicin-cardiotoxicity in rats.
Karabulut D, Ozturk E, Kaymak E, Akin AT, Yakan B.
J Biochem Mol Toxicol · journal article · DOI 10.1002/jbt.22618Development of a Thymoquinone Polymeric Anticancer Nanomedicine through Optimization of Polymer Molecular Weight and Nanoparticle Architecture.
Sunoqrot S, Alfaraj M, Hammad AM, Kasabri V, Shalabi D, Deeb AA, Hasan Ibrahim L, Shnewer K, Yousef I.
Pharmaceutics · research-article; journal article · DOI 10.3390/pharmaceutics12090811<i>In vitro</i> Evaluation of the Anti-inflammatory Effects of Thymoquinone in Osteoarthritis and <i>in silico</i> Analysis of Inter-Related Pathways in Age-Related Degenerative Diseases.
Kalamegam G, Alfakeeh SM, Bahmaid AO, AlHuwait EA, Gari MA, Abbas MM, Ahmed F, Abu-Elmagd M, Pushparaj PN.
Front Cell Dev Biol · research-article; journal article · DOI 10.3389/fcell.2020.00646Thymoquinone Upregulates Catalase Gene Expression and Preserves the Structure of the Renal Cortex of Propylthiouracil-Induced Hypothyroid Rats.
Ayuob N, Balgoon MJ, El-Mansy AA, Mubarak WA, Firgany AEL.
Oxid Med Cell Longev · research-article; journal article · DOI 10.1155/2020/3295831Covid-19 and thymoquinone: Connecting the dots.
Ahmad A, Rehman MU, Ahmad P, Alkharfy KM.
Phytother Res · letter · DOI 10.1002/ptr.6793Novel thymoquinone lipidic core nanocapsules with anisamide-polymethacrylate shell for colon cancer cells overexpressing sigma receptors.
Ramzy L, Metwally AA, Nasr M, Awad GAS.
Sci Rep · research-article; journal article · DOI 10.1038/s41598-020-67748-2Thymoquinone harbors protection against Concanavalin A-induced behavior deficit in BALB/c mice model.
Nazir S, Farooq RK, Khan H, Alam T, Javed A.
J Food Biochem · journal article · DOI 10.1111/jfbc.13348A Sensitive Rapid and Environmentally Friendly UHPLC Assay Method for the Determination of Thymoquinone in Plasma Samples and Its Analytical Application.
Alkharfy KM, Jan BL, Raish M, Haq N, Ahmad A.
J Chromatogr Sci · journal article · DOI 10.1093/chromsci/bmaa027Thymoquinone: From <i>Nigella sativa</i> to a protective pharmacological compound in managing opioid dependence and amphetamine type stimulant issues.
Mohd Adnan LH, Abu Bakar NH, Simbak N, Mohamad N, Ismail R, Ahmad NZ, Mustafa NS, Md Fauzi NFA.
Iran J Basic Med Sci · review-article; review; journal article · DOI 10.22038/ijbms.2020.41678.9841Protective effects of thymoquinone against acrylamide-induced liver, kidney and brain oxidative damage in rats.
Abdel-Daim MM, Abo El-Ela FI, Alshahrani FK, Bin-Jumah M, Al-Zharani M, Almutairi B, Alyousif MS, Bungau S, Aleya L, Alkahtani S.
Environ Sci Pollut Res Int · journal article · DOI 10.1007/s11356-020-09516-3Cytotoxicity of juglone and thymoquinone against pancreatic cancer cells.
Karki N, Aggarwal S, Laine RA, Greenway F, Losso JN.
Chem Biol Interact · research-article; journal article · DOI 10.1016/j.cbi.2020.109142Untargeted Metabolomics Identifies Key Metabolic Pathways Altered by Thymoquinone in Leukemic Cancer Cells.
AlGhamdi AA, Mohammed MRS, Zamzami MA, Al-Malki AL, Qari MH, Khan MI, Choudhry H.
Nutrients · research-article; journal article · DOI 10.3390/nu12061792Thymoquinone reduces ischemia and reperfusion-induced intestinal injury in rats, through anti-oxidative and anti-inflammatory effects.
Parlar A, Arslan SO.
Turk J Surg · research-article; journal article · DOI 10.5578/turkjsurg.4583Effects of thymoquinone in prevention of experimental contrast-induced nephropathy in rats.
Topaloğlu US, Sipahioğlu MH, Güntürk İ, Akgün H, Doğan ME, Sönmez G, Elmalı F, Yazıcı C.
Iran J Basic Med Sci · research-article; journal article · DOI 10.22038/ijbms.2019.13990Thymoquinone Potently Enhances the Activities of Classically Activated Macrophages Pulsed with Necrotic Jurkat Cell Lysates and the Production of Antitumor Th1-/M1-Related Cytokines.
Miliani M, Nouar M, Paris O, Lefranc G, Lefranc G, Mennechet F, Aribi M.
J Interferon Cytokine Res · journal article · DOI 10.1089/jir.2018.0010The synthesis and evaluation of thymoquinone analogues as anti-ovarian cancer and antimalarial agents.
Johnson-Ajinwo OR, Ullah I, Mbye H, Richardson A, Horrocks P, Li WW.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2018.02.051Thymoquinone blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic.
Yin Z, Song Y, Rehse PH.
ACS Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1021/cb3004379