Palmitoyl Serotonin Inhibits L-dopa-induced Abnormal Involuntary Movements in the Mouse Parkinson Model.
Park HY, Ryu YK, Go J, Son E, Kim KS, Kim MR.
Exp Neurobiol · research-article; journal article · DOI 10.5607/en.2016.25.4.174 PUBLIKATIONSREGISTRET
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18 träffarSpectral and 3D model studies of the interaction of orphan human cytochrome P450 2U1 with substrates and ligands.
Dhers L, Pietrancosta N, Ducassou L, Ramassamy B, Dairou J, Jaouen M, André F, Mansuy D, Boucher JL.
Biochim Biophys Acta Gen Subj · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbagen.2016.07.018Spectroscopic and dynamic properties of arachidonoyl serotonin- β-lactoglobulin complex: A molecular modeling and chemometric study.
Gholami S, Bordbar AK, Akvan N.
J Photochem Photobiol B · journal article · DOI 10.1016/j.jphotobiol.2016.07.024Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells.
Winkler K, Ramer R, Dithmer S, Ivanov I, Merkord J, Hinz B.
Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.7592Anti-Inflammatory and Antioxidant Actions of N-Arachidonoyl Serotonin in RAW264.7 Cells.
Jeon HL, Yoo JM, Lee BD, Lee SJ, Sohn EJ, Kim MR.
Pharmacology · research support, non-u.s. gov't; journal article · DOI 10.1159/000443739Inhibition of FAAH confers increased stem cell migration via PPARα.
Wollank Y, Ramer R, Ivanov I, Salamon A, Peters K, Hinz B.
J Lipid Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1194/jlr.m061473Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies.
Ducassou L, Jonasson G, Dhers L, Pietrancosta N, Ramassamy B, Xu-Li Y, Loriot MA, Beaune P, Bertho G, Lombard M, Mansuy D, André F, Boucher JL.
Biochim Biophys Acta · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbagen.2015.03.014Inhibition of FAAH, TRPV1, and COX2 by NSAID-serotonin conjugates.
Rose TM, Reilly CA, Deering-Rice CE, Brewster C, Brewster C.
Bioorg Med Chem Lett · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmcl.2014.10.064The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis.
Navarria A, Tamburella A, Iannotti FA, Micale V, Camillieri G, Gozzo L, Verde R, Imperatore R, Leggio GM, Drago F, Di Marzo V.
Pharmacol Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.phrs.2014.04.014Oxidation of endogenous N-arachidonoylserotonin by human cytochrome P450 2U1.
Siller M, Goyal S, Yoshimoto FK, Xiao Y, Wei S, Guengerich FP.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m114.550004Cross-modulation and molecular interaction at the Cav3.3 protein between the endogenous lipids and the T-type calcium channel antagonist TTA-A2.
Cazade M, Nuss CE, Bidaud I, Renger JJ, Uebele VN, Lory P, Chemin J.
Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.113.089581Effect of endocannabinoids on soybean lipoxygenase-1 activity.
Nguyen MD, Nguyen DH, Yoo JM, Myung PK, Kim MR, Sok DE.
Bioorg Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bioorg.2013.06.001Presence, formation and putative biological activities of N-acyl serotonins, a novel class of fatty-acid derived mediators, in the intestinal tract.
Verhoeckx KC, Voortman T, Balvers MG, Hendriks HF, M Wortelboer H, Witkamp RF.
Biochim Biophys Acta · journal article · DOI 10.1016/j.bbalip.2011.07.008The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice.
Costa B, Bettoni I, Petrosino S, Comelli F, Giagnoni G, Di Marzo V.
Pharmacol Res · journal article · DOI 10.1016/j.phrs.2010.02.001The case for the development of novel analgesic agents targeting both fatty acid amide hydrolase and either cyclooxygenase or TRPV1.
Fowler CJ, Naidu PS, Lichtman A, Onnis V.
Br J Pharmacol · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1111/j.1476-5381.2008.00029.xThe role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet.
Di Marzo V, Capasso R, Matias I, Aviello G, Petrosino S, Borrelli F, Romano B, Orlando P, Capasso F, Izzo AA.
Br J Pharmacol · other; research support, non-u.s. gov't; journal article · DOI 10.1038/sj.bjp.0707682New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain.
Ortar G, Cascio MG, De Petrocellis L, Morera E, Rossi F, Schiano-Moriello A, Nalli M, de Novellis V, Woodward DF, Maione S, Di Marzo V.
J Med Chem · journal article · DOI 10.1021/jm070678qIncreased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.
Izzo AA, Aviello G, Petrosino S, Orlando P, Marsicano G, Lutz B, Borrelli F, Capasso R, Nigam S, Capasso F, Di Marzo V, Endocannabinoid Research Group.
J Mol Med (Berl) · brief-report; research support, non-u.s. gov't; journal article · DOI 10.1007/s00109-007-0248-4