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Publikationer i urvalet

24 träffar

Bibliografisk träff 2016-09-06

Population pharmacokinetics of doxorubicin and doxorubicinol in patients diagnosed with non-Hodgkin's lymphoma.

Pérez-Blanco JS, Santos-Buelga D, Fernández de Gatta MD, Hernández-Rivas JM, Martín A, García MJ.

Br J Clin Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bcp.13070

Bibliografisk träff 2014-11-21

Metabolism of doxorubicin to the cardiotoxic metabolite doxorubicinol is increased in a mouse model of chronic glutathione deficiency: A potential role for carbonyl reductase 3.

Schaupp CM, White CC, Merrill GF, Kavanagh TJ.

Chem Biol Interact · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.cbi.2014.11.010

Bibliografisk träff 2014-02-28

Validation and clinical evaluation of a UHPLC method with fluorescence detector for plasma quantification of doxorubicin and doxorubicinol in haematological patients.

Pérez-Blanco JS, Fernández de Gatta Mdel M, Hernández-Rivas JM, García Sánchez MJ, Sayalero Marinero ML, González López F.

J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/j.jchromb.2014.02.034

Bibliografisk träff 2012-12-22

Simultaneous measurement of doxorubicin and reduced metabolite doxorubicinol by UHPLC-MS/MS in human plasma of HCC patients treated with TACE.

Sottani C, Poggi G, Melchiorre F, Montagna B, Minoia C.

J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/j.jchromb.2012.12.012

Bibliografisk träff 2012-11-28

The novel anthracenedione, pixantrone, lacks redox activity and inhibits doxorubicinol formation in human myocardium: insight to explain the cardiac safety of pixantrone in doxorubicin-treated patients.

Salvatorelli E, Menna P, Paz OG, Chello M, Covino E, Singer JW, Minotti G.

J Pharmacol Exp Ther · research support, non-u.s. gov't; journal article · DOI 10.1124/jpet.112.200568

Bibliografisk träff 2008-11-05

Selective determination of doxorubicin and doxorubicinol in rat plasma by HPLC with photosensitization reaction followed by chemiluminescence detection.

Ahmed S, Kishikawa N, Ohyama K, Wada M, Nakashima K, Kuroda N.

Talanta · evaluation study; journal article · DOI 10.1016/j.talanta.2008.10.043

Bibliografisk träff 2007-07-31

Quantification of pegylated liposomal doxorubicin and doxorubicinol in rat plasma by liquid chromatography/electrospray tandem mass spectroscopy: Application to preclinical pharmacokinetic studies.

Liu Y, Yang Y, Liu X, Jiang T.

Talanta · research support, non-u.s. gov't; journal article · DOI 10.1016/j.talanta.2007.07.022

Bibliografisk träff 2007-02-24

Simultaneous analysis of cyclophosphamide, doxorubicin and doxorubicinol by liquid chromatography coupled to tandem mass spectrometry.

DiFrancesco R, Griggs JJ, Donnelly J, DiCenzo R.

J Chromatogr B Analyt Technol Biomed Life Sci · research support, non-u.s. gov't; validation study; journal article · DOI 10.1016/j.jchromb.2007.02.033

Bibliografisk träff 2007-01-02

Toxicokinetics of the active doxorubicin metabolite, doxorubicinol, in sulphur-crested cockatoos (Cacatua galerita).

Gilbert CM, Filippich LJ, McGeary RP, Charles BG.

Res Vet Sci · clinical trial; research support, non-u.s. gov't; journal article · DOI 10.1016/j.rvsc.2006.11.005

Bibliografisk träff 2006-10-01

Pharmacokinetics of doxorubicinol in dogs.

Gilbert CM, Filippich LJ, McGeary RP, Charles BG.

J Vet Pharmacol Ther · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1365-2885.2006.00782.x

Bibliografisk träff 2006-08-01

Separation of doxorubicin and doxorubicinol by cyclodextrin-modified micellar electrokinetic capillary chromatography.

Eder AR, Chen JS, Arriaga EA.

Electrophoresis · journal article; research support, n.i.h., extramural · DOI 10.1002/elps.200600025

Bibliografisk träff 2006-04-13

Paclitaxel and docetaxel stimulation of doxorubicinol formation in the human heart: implications for cardiotoxicity of doxorubicin-taxane chemotherapies.

Salvatorelli E, Menna P, Cascegna S, Liberi G, Calafiore AM, Gianni L, Minotti G.

J Pharmacol Exp Ther · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1124/jpet.106.103846

Bibliografisk träff 2005-09-15

Simultaneous liquid chromatographic determination of doxorubicin and its major metabolite doxorubicinol in parrot plasma.

Gilbert CM, McGeary RP, Filippich LJ, Norris RL, Charles BG.

J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/j.jchromb.2005.08.017

Bibliografisk träff 2003-01-10

A population pharmacokinetic model for doxorubicin and doxorubicinol in the presence of a novel MDR modulator, zosuquidar trihydrochloride (LY335979).

Callies S, de Alwis DP, Wright JG, Sandler A, Burgess M, Aarons L.

Cancer Chemother Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00280-002-0542-3

Bibliografisk träff 2001-07-01

Effects of doxorubicinol on excitation--contraction coupling in guinea pig ventricular myocytes.

Wang GX, Wang YX, Zhou XB, Korth M.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/s0014-2999(01)01096-2

Bibliografisk träff 2000-02-01

Effect of cyclodextrins on the stability of adriamycin, adriamycinol, adriamycinone and daunomycin.

Emara S, Morita I, Tamura K, Razee S, Masujima T, Mohamed HA, El-Gizawy SM, El-Rabbat NA.

Talanta · journal article · DOI 10.1016/s0039-9140(99)00280-5

Bibliografisk träff 1999-01-01

Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein.

van Asperen J, van Tellingen O, Tijssen F, Schinkel AH, Beijnen JH.

Br J Cancer · research-article; journal article · DOI 10.1038/sj.bjc.6690019

Bibliografisk träff 1999-01-01

Determination of doxorubicin and doxorubicinol in plasma of cancer patients by high-performance liquid chromatography.

de Bruijn P, Verweij J, Loos WJ, Kolker HJ, Planting AS, Nooter K, Stoter G, Sparreboom A.

Anal Biochem · journal article · DOI 10.1006/abio.1998.2943

Bibliografisk träff 1997-06-01

Pharmacokinetics of adriamycin and adriamycinol after intravenous administration of adriamycin to rats with water-deprivation for 48 hours.

Lee HJ, Lee MG.

Res Commun Mol Pathol Pharmacol · research support, non-u.s. gov't; journal article

Bibliografisk träff 1996-02-01

Effect of the paclitaxel vehicle, Cremophor EL, on the pharmacokinetics of doxorubicin and doxorubicinol in mice.

Webster LK, Cosson EJ, Stokes KH, Millward MJ.

Br J Cancer · comparative study; research-article; journal article · DOI 10.1038/bjc.1996.90

Bibliografisk träff 1995-04-01

A sensitive procedure for the quantitation of free and N-(2-hydroxypropyl) methacrylamide polymer-bound doxorubicin (PK1) and some of its metabolites, 13-dihydrodoxorubicin, 13-dihydrodoxorubicinone and doxorubicinone, in human plasma and urine by reversed-phase HPLC with fluorimetric detection.

Fraier D, Frigerio E, Pianezzola E, Strolin Benedetti M, Cassidy J, Vasey P.

J Pharm Biomed Anal · journal article · DOI 10.1016/0731-7085(95)01301-z

Bibliografisk träff 1993-11-01

Time-related increases in cardiac concentrations of doxorubicinol could interact with doxorubicin to depress myocardial contractile function.

Mushlin PS, Cusack BJ, Boucek RJ, Andrejuk T, Li X, Olson RD.

Br J Pharmacol · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1111/j.1476-5381.1993.tb13909.x

Bibliografisk träff 1992-01-01

Doxorubicin and doxorubicinol plasma concentrations and excretion in parotid saliva.

Bressolle F, Jacquet JM, Galtier M, Jourdan J, Donadio D, Rossi JF.

Cancer Chemother Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/bf00686315

Bibliografisk träff 1988-05-01

Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol.

Olson RD, Mushlin PS, Brenner DE, Fleischer S, Cusack BJ, Chang BK, Boucek RJ.

Proc Natl Acad Sci U S A · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1073/pnas.85.10.3585