DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.
Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015 PUBLIKATIONSREGISTRET
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6 träffarTranslating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.
PLoS Comput Biol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1371/journal.pcbi.1002310FDA-approved drug labeling for the study of drug-induced liver injury.
Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W.
Drug Discov Today · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/j.drudis.2011.05.007Predicting phospholipidosis using machine learning.
Lowe R, Glen RC, Mitchell JB.
Mol Pharm · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/mp100103eDevelopment of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Kruhlak NL, Choi SS, Contrera JF, Weaver JL, Willard JM, Hastings KL, Sancilio LF.
Toxicol Mech Methods · journal article · DOI 10.1080/15376510701857262Evaluation of a published in silico model and construction of a novel Bayesian model for predicting phospholipidosis inducing potential.
Pelletier DJ, Gehlhaar D, Tilloy-Ellul A, Johnson TO, Greene N.
J Chem Inf Model · journal article · DOI 10.1021/ci6004542