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Publikationer i urvalet

14 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2006-09-01

Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.

Mohler ML, Kang GS, Hong SS, Patil R, Kirichenko OV, Li W, Rakov IM, Geisert EE, Miller DD.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm060020x

Bibliografisk träff 2000-10-01

Tetrahydroisoquinoline derivatives containing a benzenesulfonamide moiety as potent, selective human beta3 adrenergic receptor agonists.

Parmee ER, Brockunier LL, He J, Singh SB, Candelore MR, Cascieri MA, Deng L, Liu Y, Tota L, Wyvratt MJ, Fisher MH, Weber AE.

Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(00)00459-5

Bibliografisk träff 2000-02-01

Synthesis and human beta-adrenoceptor activity of 1-(3,5-diiodo-4- methoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-6-ol derivatives in vitro.

He Y, Nikulin VI, Vansal SS, Feller DR, Miller DD.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm990463j

Bibliografisk träff 1999-06-01

2-Amino-4-benzyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridines: novel selective beta3-adrenoceptor agonists.

Zheng W, Nikulin VI, Konkar AA, Vansal SS, Shams G, Feller DR, Miller DD.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm990012z

Bibliografisk träff 1997-01-01

Synthesis and evaluation of trimetoquinol derivatives: novel thromboxane A2/prostaglandin H2 antagonists with diminished beta-adrenergic agonist activity.

Christoff JJ, Bradley L, Miller DD, Lei L, Rodriguez F, Fraundorfer P, Romstedt K, Shams G, Feller DR.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm950896w

Bibliografisk träff 1996-09-01

Iodinated analogs of trimetoquinol as highly potent and selective beta 2-adrenoceptor ligands.

De Los Angeles JE, Nikulin VI, Shams G, Konkar AA, Mehta R, Feller DR, Miller DD.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm960208o

Bibliografisk träff 1992-02-01

Synthesis of halogenated trimetoquinol derivatives and evaluation of their beta-agonist and thromboxane A2 (TXA2) antagonist activities.

Markovich KM, Tantishaiyakul V, Hamada A, Miller DD, Romstedt KJ, Shams G, Shin Y, Fraundorfer PF, Doyle K, Feller DR.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00081a007

Bibliografisk träff 1986-11-01

6,7-Dichloro-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline . A structurally novel beta-adrenergic receptor blocking agent.

Kaiser C, Oh HJ, Garcia-Slanga BJ, Sulpizio AC, Hieble JP, Wawro JE, Kruse LI.

J Med Chem · journal article · DOI 10.1021/jm00161a039

Bibliografisk träff 1986-02-01

Synthesis and investigation of the beta-adrenoceptor agonist and platelet antiaggregatory properties of 1,7,8-trisubstituted 2,3,4,5-tetrahydro-1H-2-benzazepine analogues of trimetoquinol.

Clark MT, Chang J, Navran SS, Huzoor-Akbar, Mukhopadhyay A, Amin H, Feller DR, Miller DD.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00152a003

Bibliografisk träff 1981-08-01

Selective and potent beta 2-adrenoceptor agents within the tetrahydroisoquinoline class: effect of methyl substitution at the benzylic carbon of the 1-(3,4,5-trimethoxybenzyl) group of trimetoquinol.

Sober DJ, Chang J, Fowble JW, Mukhopadhyay A, Feller DR, Miller DD, Fairchild EH.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00140a011

Bibliografisk träff 1980-06-01

Mammalian alkaloids. 8. Synthesis and biological effects of tetrahydropapaveroline related 1-benzyltetrahydroisoquinolines.

Brossi A, Rice KC, Mak CP, Reden J, Jacobson AE, Nimitkitpaisan Y, Skolnick P, Daly J.

J Med Chem · journal article · DOI 10.1021/jm00180a013

Bibliografisk träff 1978-11-01

Synthesis and beta-adrenoceptor activity of the erythro and threo isomers of substituted alpha-hydroxytrimetoquinol.

Osei-Gyimah P, Piascik MT, Fowble JW, Feller DR, Miller DD.

J Med Chem · journal article · DOI 10.1021/jm00209a019

Bibliografisk träff 1976-06-01

Synthesis and biological evaluation of fragmented derivatives of tetrahydroisoquinolines. 3. Trimetoquinol studies.

Miller DD, Kador PF, Venkatraman R, Feller DR.

J Med Chem · journal article · DOI 10.1021/jm00228a005