Immobilized Metal Affinity Chromatography as a Drug Discovery Platform for Metalloenzyme Inhibitors.
Roth L, Gotsbacher MP, Codd R.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c01541 PUBLIKATIONSREGISTRET
Gå till forskningen.
Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.
Publikationer som ChEBI hänvisar till för omapatrilat. Visa hela publikationsregistret
En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.
Publikationer i urvalet
9 träffarMolecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin-Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme.
Sharma U, Cozier GE, Sturrock ED, Acharya KR.
J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/acs.jmedchem.0c00441Discovery of TD-0212, an Orally Active Dual Pharmacology AT<sub>1</sub> Antagonist and Neprilysin Inhibitor (ARNI).
McKinnell RM, Fatheree P, Choi SK, Gendron R, Jendza K, Olson Blair B, Budman J, Hill CM, Hegde LG, Yu C, McConn D, Hegde SS, Marquess DG, Klein U.
ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.8b00462Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.
Cozier GE, Arendse LB, Schwager SL, Sturrock ED, Acharya KR.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.8b01309Phosphinic tripeptides as dual angiotensin-converting enzyme C-domain and endothelin-converting enzyme-1 inhibitors.
Jullien N, Makritis A, Georgiadis D, Beau F, Yiotakis A, Dive V.
J Med Chem · journal article · DOI 10.1021/jm9010803Synthesis and antihypertensive effects of new methylthiomorpholinphenol derivatives.
Velázquez AM, Martínez L, Abrego V, Balboa MA, Torres LA, Camacho B, Díaz-Barriga S, Romero A, López-Castañares R, Angeles E.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2007.04.003N-formyl hydroxylamine containing dipeptides: generation of a new class of vasopeptidase inhibitors.
Robl JA, Simpkins LM, Asaad MM.
Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(99)00671-xVasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides.
Robl JA, Sulsky R, Sieber-McMaster E, Ryono DE, Cimarusti MP, Simpkins LM, Karanewsky DS, Chao S, Asaad MM, Seymour AA, Fox M, Smith PL, Trippodo NC.
J Med Chem · journal article · DOI 10.1021/jm980542fDual metalloprotease inhibitors: mercaptoacetyl-based fused heterocyclic dipeptide mimetics as inhibitors of angiotensin-converting enzyme and neutral endopeptidase.
Robl JA, Sun CQ, Stevenson J, Ryono DE, Simpkins LM, Cimarusti MP, Dejneka T, Slusarchyk WA, Chao S, Stratton L, Misra RN, Bednarz MS, Asaad MM, Cheung HS, Abboa-Offei BE, Smith PL, Mathers PD, Fox M, Schaeffer TR, Seymour AA, Trippodo NC.
J Med Chem · journal article · DOI 10.1021/jm970041e