ActiQs / Forskning

PUBLIKATIONSREGISTRET

Gå till forskningen.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för nalfurafine. Visa hela publikationsregistret

En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publikationer i urvalet

15 träffar

Bibliografisk träff 2022-09-22

A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse.

Khan MIH, Sawyer BJ, Akins NS, Le HV.

Eur J Med Chem · systematic review; journal article · DOI 10.1016/j.ejmech.2022.114785

Bibliografisk träff 2022-07-28

<b>SLL-627</b> Is a Highly Selective and Potent κ Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity.

Kong L, Shu X, Tang S, Ye R, Sun H, Jiang S, Li Z, Chai J, Fang Y, Lan Y, Yu L, Xie Q, Fu W, Wang Y, Li W, Qiu Z, Liu J, Shao L.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.2c00014

Bibliografisk träff 2022-01-07

Effect of removal of the 14-hydroxy group on the affinity of the 4,5-epoxymorphinan derivatives for orexin and opioid receptors.

Katoh K, Yamamoto N, Ishikawa Y, Irukayama-Tomobe Y, Tanimura R, Saitoh T, Nagumo Y, Kutsumura N, Yanagisawa M, Nagase H.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2022.128527

Bibliografisk träff 2020-06-19

Discovery of attenuation effect of orexin 1 receptor to aversion of nalfurafine: Synthesis and evaluation of D-nor-nalfurafine derivatives and analyses of the three active conformations of nalfurafine.

Nagumo Y, Katoh K, Iio K, Saitoh T, Kutsumura N, Yamamoto N, Ishikawa Y, Irukayama-Tomobe Y, Ogawa Y, Baba T, Tanimura R, Yanagisawa M, Nagase H.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2020.127360

Bibliografisk träff 2019-09-16

Progress in the development of more effective and safer analgesics for pain management.

Turnaturi R, Chiechio S, Salerno L, Rescifina A, Pittalà V, Cantarella G, Tomarchio E, Parenti C, Pasquinucci L.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2019.111701

Bibliografisk träff 2018-07-10

Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential.

Tan L, Yan W, McCorvy JD, Cheng J.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.8b00435

Bibliografisk träff 2017-06-15

Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives.

Kutsumura N, Koyama Y, Nagumo Y, Nakajima R, Miyata Y, Yamamoto N, Saitoh T, Yoshida N, Iwata S, Nagase H.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2017.06.026

Bibliografisk träff 2017-03-13

In silico design of novel probes for the atypical opioid receptor MRGPRX2.

Lansu K, Karpiak J, Liu J, Huang XP, McCorvy JD, Kroeze WK, Che T, Nagase H, Carroll FI, Jin J, Shoichet BK, Roth BL.

Nat Chem Biol · research-article; journal article · DOI 10.1038/nchembio.2334

Bibliografisk träff 2015-09-16

Conformationally restricted κ-opioid receptor agonists: Synthesis and pharmacological evaluation of diastereoisomeric and enantiomeric decahydroquinoxalines.

Molenveld P, Bouzanne des Mazery R, Sterk GJ, Storcken RP, Autar R, van Oss B, van der Haas RN, Fröhlich R, Schepmann D, Wünsch B, Soeberdt M.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2015.09.040

Bibliografisk träff 2014-09-21

Design, synthesis, and structure-activity relationship of novel opioid κ receptor selective agonists: α-iminoamide derivatives with an azabicyclo[2.2.2]octene skeleton.

Watanabe Y, Kitazawa S, Fujii H, Nemoto T, Hirayama S, Iwai T, Gouda H, Hirono S, Nagasea H.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2014.09.029

Bibliografisk träff 2013-04-03

Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton having a 7-amide side chain and their pharmacologies.

Watanabe Y, Kitazawa S, Nemoto T, Hirayama S, Iwai T, Fujii H, Nagase H.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2013.03.026

Bibliografisk träff 2012-03-08

Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton and their pharmacologies.

Watanabe Y, Kitazawa S, Fujii H, Nemoto T, Hirayama S, Nagase H.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2012.03.001

Bibliografisk träff 2010-12-21

Synthesis of 6,14-epoxymorphinan derivatives and their pharmacologies.

Nemoto T, Yamamoto N, Watanabe A, Fujii H, Hasebe K, Nakajima M, Mochizuki H, Nagase H.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.12.035

Bibliografisk träff 2010-07-13

Synthesis of pyrrolomorphinan derivatives as kappa opioid agonists.

Fujii H, Ida Y, Hanamura S, Osa Y, Nemoto T, Nakajima M, Hasebe K, Nakao K, Mochizuki H, Nagase H.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2010.07.035

Bibliografisk träff 2007-10-24

Standard protecting groups create potent and selective kappa opioids: salvinorin B alkoxymethyl ethers.

Munro TA, Duncan KK, Xu W, Wang Y, Liu-Chen LY, Carlezon WA, Cohen BM, Béguin C.

Bioorg Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2007.10.067