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Publikationer i urvalet

8 träffar

Bibliografisk träff 2017-08-09

Effectiveness and Tolerability of Anticoagulants for Thromboprophylaxis after Major Joint Surgery: a Network Meta-Analysis.

Wang Z, Zheng J, Zhao Y, Xiang Y, Chen X, Jin Y.

Cell Physiol Biochem · network meta-analysis; journal article · DOI 10.1159/000479840

Bibliografisk träff 2016-02-04

Theoretical Study of Molecular Structure and Physicochemical Properties of Novel Factor Xa Inhibitors and Dual Factor Xa and Factor IIa Inhibitors.

Remko M, Remková A, Broer R.

Molecules · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/molecules21020185

Bibliografisk träff 2015-11-05

Safety, pharmacokinetics, and pharmacodynamics of PD 0348292, an oral, direct factor Xa inhibitor, after single and multiple dosings in healthy subjects.

Xuan D, McBride S, Wastall P, Porcari A, DiCarlo L, Boyd RA.

Clin Pharmacol Drug Dev · clinical trial, phase i; randomized controlled trial; journal article · DOI 10.1002/cpdd.232

Bibliografisk träff 2013-08-01

An adaptive-design dose-ranging study of PD 0348292, an oral factor Xa inhibitor, for thromboprophylaxis after total knee replacement surgery.

Cohen AT, Boyd RA, Mandema JW, Dicarlo L, Pak R, A5571010 Investigators.

J Thromb Haemost · clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1111/jth.12328

Bibliografisk träff 2009-01-01

Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development.

Eriksson BI, Quinlan DJ, Weitz JI.

Clin Pharmacokinet · comparative study; research support, non-u.s. gov't; review; journal article · DOI 10.2165/0003088-200948010-00001

Bibliografisk träff 2008-04-01

Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis.

Karnicki K, Leadley RJ, Baxi S, Peterson T, Wysokinski W, McBane RD.

Thromb Haemost · comparative study; journal article · DOI 10.1160/th07-09-0576

Bibliografisk träff 2007-12-20

Iliac venous stenting: antithrombotic efficacy of PD0348292, an oral direct Factor Xa inhibitor, compared with antiplatelet agents in pigs.

McBane RD, Leadley RJ, Baxi SM, Karnicki K, Wysokinski W.

Arterioscler Thromb Vasc Biol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1161/atvbaha.107.158691

Bibliografisk träff 2007-08-01

The discovery of (2R,4R)-N-(4-chlorophenyl)-N- (2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidine-1,2-dicarboxamide (PD 0348292), an orally efficacious factor Xa inhibitor.

Kohrt JT, Bigge CF, Bryant JW, Casimiro-Garcia A, Chi L, Cody WL, Dahring T, Dudley DA, Filipski KJ, Haarer S, Heemstra R, Janiczek N, Narasimhan L, McClanahan T, Peterson JT, Sahasrabudhe V, Schaum R, Van Huis CA, Welch KM, Zhang E, Leadley RJ, Edmunds JJ.

Chem Biol Drug Des · journal article · DOI 10.1111/j.1747-0285.2007.00539.x