Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathway.
Moon SH, Kim I, Kim SH.
Arch Pharm Res · journal article · DOI 10.1007/s12272-017-0964-4 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
21 träffarMollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation.
Wang Z, Li MY, Mi C, Wang KS, Ma J, Jin X.
Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms18081619Simultaneous Determination of Purpurin, Munjistin and Mollugin in Rat Plasma by Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry: Application to a Pharmacokinetic Study after Oral Administration of Rubia cordifolia L. Extract.
Gao M, Yang J, Wang Z, Yang B, Kuang H, Liu L, Wang L, Yang C.
Molecules · research-article; journal article · DOI 10.3390/molecules21060717Syntheses and anti-inflammatory activity of azamollugin derivatives.
Nishino H, Nakajima Y, Kakubari Y, Asami N, Deguchi J, Nugroho AE, Hirasawa Y, Kaneda T, Kawasaki Y, Goda Y, Morita H.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2015.11.081Oxomollugin, a potential inhibitor of lipopolysaccharide-induced nitric oxide production including nuclear factor kappa B signals.
Morita H, Nishino H, Nakajima Y, Kakubari Y, Nakata A, Deguchi J, Nugroho AE, Hirasawa Y, Kaneda T, Kawasaki Y, Goda Y.
J Nat Med · research support, non-u.s. gov't; journal article · DOI 10.1007/s11418-015-0927-3Simultaneous determination of alizarin and rubimaillin in Rubia cordifolia by ultrasound-assisted ionic liquid-reversed phase liquid chromatography.
Yang HS, Wang J, Guo C, Liu W, Chen YY, Wei JF, Kang WY.
Zhongguo Zhong Yao Za Zhi · journal article · DOI 10.4268/cjcmm20151324Mollugin from Rubea cordifolia suppresses receptor activator of nuclear factor-κB ligand-induced osteoclastogenesis and bone resorbing activity in vitro and prevents lipopolysaccharide-induced bone loss in vivo.
Baek JM, Kim JY, Jung Y, Moon SH, Choi MK, Kim SH, Lee MS, Kim I, Oh J.
Phytomedicine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.phymed.2014.10.008New cytotoxic naphthohydroquinone dimers from Rubia alata.
Zhao SM, Wang Z, Zeng GZ, Song WW, Chen XQ, Li XN, Tan NH.
Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol502603fMollugin induces tumor cell apoptosis and autophagy via the PI3K/AKT/mTOR/p70S6K and ERK signaling pathways.
Zhang L, Wang H, Zhu J, Xu J, Ding K.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2014.05.101Effects of lovastatin, clomazone and methyl jasmonate treatment on the accumulation of purpurin and mollugin in cell suspension cultures of Rubia cordifolia.
Fan X, Hu GS, Li N, Han ZF, Jia JM.
Chin J Nat Med · research support, non-u.s. gov't; journal article · DOI 10.1016/s1875-5364(13)60058-8Involvement of Nrf2-mediated upregulation of heme oxygenase-1 in mollugin-induced growth inhibition and apoptosis in human oral cancer cells.
Lee YM, Auh QS, Lee DW, Kim JY, Jung HJ, Lee SH, Kim EC.
Biomed Res Int · retracted publication; research support, non-u.s. gov't; research-article; journal article · DOI 10.1155/2013/210604Mollugin inhibits proliferation and induces apoptosis by suppressing fatty acid synthase in HER2-overexpressing cancer cells.
Do MT, Hwang YP, Kim HG, Na M, Jeong HG.
J Cell Physiol · research support, non-u.s. gov't; journal article · DOI 10.1002/jcp.24258Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells.
Tran TP, Kim HG, Choi JH, Na MK, Jeong HG.
Phytomedicine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.phymed.2013.01.014Mollugin inhibits the inflammatory response in lipopolysaccharide-stimulated RAW264.7 macrophages by blocking the Janus kinase-signal transducers and activators of transcription signaling pathway.
Zhu ZG, Jin H, Yu PJ, Tian YX, Zhang JJ, Wu SG.
Biol Pharm Bull · research support, non-u.s. gov't; journal article · DOI 10.1248/bpb.b12-00804Selective inhibitory effects of mollugin on CYP1A2 in human liver microsomes.
Kim H, Choi HK, Jeong TC, Jahng Y, Kim DH, Lee SH, Lee S.
Food Chem Toxicol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.fct.2012.09.013[Study on intestinal absorption of mollugin and purpurin in rats].
Wang K, Chen X, Shan M, Ding A.
Zhongguo Zhong Yao Za Zhi · journal article · DOI 10.4268/cjcmm20121234Neuroprotective and anti-inflammatory effects of mollugin via up-regulation of heme oxygenase-1 in mouse hippocampal and microglial cells.
Jeong GS, Lee DS, Kim DC, Jahng Y, Son JK, Lee SH, Kim YC.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2010.12.027Effect of mollugin on apoptosis and adipogenesis of 3T3-L1 preadipocytes.
Jun do Y, Han CR, Choi MS, Bae MA, Woo MH, Kim YH.
Phytother Res · research support, non-u.s. gov't; journal article · DOI 10.1002/ptr.3329Anti-inflammatory action of mollugin and its synthetic derivatives in HT-29 human colonic epithelial cells is mediated through inhibition of NF-kappaB activation.
Kim KJ, Lee JS, Kwak MK, Choi HG, Yong CS, Kim JA, Lee YR, Lyoo WS, Park YJ.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2009.09.008Mollugin induces apoptosis in human Jurkat T cells through endoplasmic reticulum stress-mediated activation of JNK and caspase-12 and subsequent activation of mitochondria-dependent caspase cascade regulated by Bcl-xL.
Kim SM, Park HS, Jun DY, Woo HJ, Woo MH, Yang CH, Kim YH.
Toxicol Appl Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.taap.2009.08.024The molecular target of rubimaillin in the inhibition of lipid droplet accumulation in macrophages.
Matsuda D, Ohshiro T, Ohba M, Jiang W, Hong B, Si S, Tomoda H.
Biol Pharm Bull · research support, non-u.s. gov't; journal article · DOI 10.1248/bpb.32.1317