ATPase inhibitory factor 1 inhibition improves the antitumor of YC-1 against hepatocellular carcinoma.
Ding X, Kong J, Xu W, Dong S, Du Y, Yao C, Gao J, Ke S, Wang S, Sun W.
Oncol Lett · research-article; journal article · DOI 10.3892/ol.2018.9266 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
16 träffarTherapeutic window for YC‑1 following glutamate‑induced neuronal damage and transient focal cerebral ischemia.
Tai SH, Lee WT, Lee AC, Lin YW, Hung HY, Huang SY, Wu TS, Lee EJ.
Mol Med Rep · research-article; journal article · DOI 10.3892/mmr.2018.8660YC-1 alleviates bone loss in ovariectomized rats by inhibiting bone resorption and inducing extrinsic apoptosis in osteoclasts.
Wang JW, Yeh CB, Chou SJ, Lu KC, Chu TH, Chen WY, Chien JL, Yen MH, Chen TH, Shyu JF.
J Bone Miner Metab · journal article · DOI 10.1007/s00774-017-0866-zLow-dose YC-1 combined with glucose and insulin selectively induces apoptosis in hypoxic gastric carcinoma cells by inhibiting anaerobic glycolysis.
Wakiyama K, Kitajima Y, Tanaka T, Kaneki M, Yanagihara K, Aishima S, Nakamura J, Noshiro H.
Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41598-017-12929-9Modulation of HIF-1α and STAT3 signaling contributes to anti-angiogenic effect of YC-1 in mice with liver fibrosis.
Lee TY, Leu YL, Wen CK.
Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.21039[Effect of targeted inhibition of hypoxia-inducible factor-1α by 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole on the progression of non-alcoholic fatty liver disease in rats].
Shen WD, Zhang W, Xu QH, Liu PF.
Zhonghua Gan Zang Bing Za Zhi · research-article; journal article · DOI 10.3760/cma.j.issn.1007-3418.2016.10.007Combination therapy with local radiofrequency ablation and YC-1 inhibits the proliferation and metastasis of hepatocellular carcinoma through activating β-catenin signaling.
Zhao W, Li X, Li Z.
Pharmazie · journal article · DOI 10.1691/ph.2016.6602Potent ameliorating effect of Hypoxia-inducible factor 1α (HIF-1α) antagonist YC-1 on combined allergic rhinitis and asthma syndrome (CARAS) in Rats.
Wang X, Liu C, Wu L, Zhu S.
Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2016.07.040The effect of 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole (YC-1) on cell viability under hypoxia.
Tsui L, Fong TH, Wang IJ.
Mol Vis · research support, non-u.s. gov't; research-article; journal articleThe soluble guanylyl cyclase activator YC-1 increases intracellular cGMP and cAMP via independent mechanisms in INS-1E cells.
Ramos-Espiritu LS, Hess KC, Buck J, Levin LR.
J Pharmacol Exp Ther · research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/jpet.111.184135Binding of YC-1/BAY 41-2272 to soluble guanylate cyclase: A new perspective to the mechanism of activation.
Pal B, Kitagawa T.
Biochem Biophys Res Commun · review; journal article · DOI 10.1016/j.bbrc.2010.05.122YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent components.
Martin E, Lee YC, Murad F.
Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1073/pnas.231486198Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity.
Galle J, Zabel U, Hübner U, Hatzelmann A, Wagner B, Wanner C, Schmidt HH.
Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/sj.bjp.0702495Mechanism of YC-1-induced activation of soluble guanylyl cyclase.
Friebe A, Koesling D.
Mol Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1124/mol.53.1.123YC-1, a nitric oxide-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice.
Teng CM, Wu CC, Ko FN, Lee FY, Kuo SC.
Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/s0014-2999(96)00911-9YC-1, a novel activator of platelet guanylate cyclase.
Ko FN, Wu CC, Kuo SC, Lee FY, Teng CM.
Blood · research support, non-u.s. gov't; journal article · DOI 10.1182/blood.v84.12.4226.bloodjournal84124226