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Publikationer i urvalet

7 träffar

Bibliografisk träff 2019-01-11

Mass Spectrometry-based Label-free Quantitative Proteomics To Study the Effect of 3PO Drug at Cellular Level.

Nukala SB, Baron G, Aldini G, Carini M, D'Amato A.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.8b00593

Bibliografisk träff 2015-11-01

Inhibition of Growth of Bladder Cancer Cells by 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one in Combination with Other Compounds Affecting Glucose Metabolism.

Lea MA, Altayyar M, desBordes C.

Anticancer Res · research support, non-u.s. gov't; journal article

Bibliografisk träff 2015-04-13

Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.

Boyd S, Brookfield JL, Critchlow SE, Cumming IA, Curtis NJ, Debreczeni J, Degorce SL, Donald C, Evans NJ, Groombridge S, Hopcroft P, Jones NP, Kettle JG, Lamont S, Lewis HJ, MacFaull P, McLoughlin SB, Rigoreau LJ, Smith JM, St-Gallay S, Stock JK, Turnbull AP, Wheatley ER, Winter J, Wingfield J.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.5b00352

Bibliografisk träff 2014-01-23

Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism.

Klarer AC, O'Neal J, Imbert-Fernandez Y, Clem A, Ellis SR, Clark J, Clem B, Chesney J, Telang S.

Cancer Metab · research-article; journal article · DOI 10.1186/2049-3002-2-2

Bibliografisk träff 2013-12-12

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

Schoors S, De Bock K, Cantelmo AR, Georgiadou M, Ghesquière B, Cauwenberghs S, Kuchnio A, Wong BW, Quaegebeur A, Goveia J, Bifari F, Wang X, Blanco R, Tembuyser B, Cornelissen I, Bouché A, Vinckier S, Diaz-Moralli S, Gerhardt H, Telang S, Cascante M, Chesney J, Dewerchin M, Carmeliet P.

Cell Metab · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cmet.2013.11.008

Bibliografisk träff 2012-05-16

Small molecule inhibition of 6-phosphofructo-2-kinase suppresses t cell activation.

Telang S, Clem BF, Klarer AC, Clem AL, Trent JO, Bucala R, Chesney J.

J Transl Med · research-article; journal article · DOI 10.1186/1479-5876-10-95

Bibliografisk träff 2008-01-01

Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.

Clem B, Telang S, Clem A, Yalcin A, Meier J, Simmons A, Rasku MA, Arumugam S, Dean WL, Eaton J, Lane A, Trent JO, Chesney J.

Mol Cancer Ther · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1158/1535-7163.mct-07-0482