Complement protein C5a enhances the β-amyloid-induced neuro-inflammatory response in microglia in Alzheimer's disease.
An XQ, Xi W, Gu CY, Huang X.
Med Sci (Paris) · journal article · DOI 10.1051/medsci/201834f120 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
7 träffarAnti-inflammatory Effects of PMX205 in Mouse Macrophage Periodontitis Model.
Li G, Pan J, Tang Q, Liu X, Wang L, Meng Y, Yu W.
Iran J Immunol · journal article · DOI 10.22034/iji.2018.39373Development and validation of a LC-MS/MS assay for pharmacokinetic studies of complement C5a receptor antagonists PMX53 and PMX205 in mice.
Kumar V, Lee JD, Clark RJ, Woodruff TM.
Sci Rep · research support, non-u.s. gov't; research-article; validation study; journal article · DOI 10.1038/s41598-018-26387-4Pharmacological inhibition of complement C5a-C5a<sub>1</sub> receptor signalling ameliorates disease pathology in the hSOD1<sup>G93A</sup> mouse model of amyotrophic lateral sclerosis.
Lee JD, Kumar V, Fung JN, Ruitenberg MJ, Noakes PG, Woodruff TM.
Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bph.13730Treatment with the C5a receptor/CD88 antagonist PMX205 reduces inflammation in a murine model of allergic asthma.
Staab EB, Sanderson SD, Wells SM, Poole JA.
Int Immunopharmacol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.intimp.2014.05.008The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10.
Jain U, Woodruff TM, Stadnyk AW.
Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1476-5381.2012.02183.xImproving the Fmoc Solid Phase Synthesis of the Cyclic Hexapeptide Complement C5a Antagonist, PMX205.
Delisle Milton RC, Milton SC, Chamberlin AR.
Int J Pept Res Ther · research-article; journal article · DOI 10.1007/s10989-011-9273-9