Orthosteric and allosteric action of the C5a receptor antagonists.
Liu H, Kim HR, Deepak RNVK, Wang L, Chung KY, Fan H, Wei Z, Zhang C.
Nat Struct Mol Biol · research support, non-u.s. gov't; journal article · DOI 10.1038/s41594-018-0067-z PUBLIKATIONSREGISTRET
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8 träffarDevelopment and validation of a LC-MS/MS assay for pharmacokinetic studies of complement C5a receptor antagonists PMX53 and PMX205 in mice.
Kumar V, Lee JD, Clark RJ, Woodruff TM.
Sci Rep · research support, non-u.s. gov't; research-article; validation study; journal article · DOI 10.1038/s41598-018-26387-4RP S19 C-terminal peptide trimer acts as a C5a receptor antagonist.
Nishiura H, Kawakami T, Kawabe M, Kato-Kogoe N, Yamada N, Nakasho K, Yamanegi K.
Biochem Biophys Rep · research-article; journal article · DOI 10.1016/j.bbrep.2016.05.006Improvements in neuroelectrophysiological and rear limb functions in rats with spinal cord injury after Schwann cell transplantation in combination with a C5a receptor antagonist.
Zhang SQ, Wu MF, Peng CG, Lv Y, Wu DK, Liu J, Yang Q.
Genet Mol Res · journal article · DOI 10.4238/2015.november.25.4C3a and C5a receptor antagonists ameliorate endothelial-myofibroblast transition via the Wnt/β-catenin signaling pathway in diabetic kidney disease.
Li L, Chen L, Zang J, Tang X, Liu Y, Zhang J, Bai L, Yin Q, Lu Y, Cheng J, Fu P, Liu F.
Metabolism · research support, non-u.s. gov't; journal article · DOI 10.1016/j.metabol.2015.01.014Neuroprotective effects of argatroban and C5a receptor antagonist (PMX53) following intracerebral haemorrhage.
Li G, Fan RM, Chen JL, Wang CM, Zeng YC, Han C, Jiao S, Xia XP, Chen W, Yao ST.
Clin Exp Immunol · research support, non-u.s. gov't; journal article · DOI 10.1111/cei.12220Overproduction of a C5a receptor antagonist (C5aRA) in Escherichia coli.
Jang SH, Jeong KJ.
Protein Expr Purif · research support, non-u.s. gov't; journal article · DOI 10.1016/j.pep.2013.03.004Identification of a new class of small molecule C5a receptor antagonists.
Chen JJ, Cole DC, Ciszewski G, Crouse K, Ellingboe JW, Nowak P, Tawa GJ, Berstein G, Li W.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.11.058