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Publikationer i urvalet

11 träffar

Bibliografisk träff 2018-04-16

Final results of a phase 2, open-label study of indisulam, idarubicin, and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome.

Assi R, Kantarjian HM, Kadia TM, Pemmaraju N, Jabbour E, Jain N, Daver N, Estrov Z, Uehara T, Owa T, Cortes JE, Borthakur G.

Cancer · clinical trial, phase ii; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/cncr.31398

Bibliografisk träff 2017-03-16

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

Han T, Han T, Goralski M, Gaskill N, Capota E, Kim J, Ting TC, Xie Y, Williams NS, Nijhawan D.

Science · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1126/science.aal3755

Bibliografisk träff 2012-02-17

Therapeutic potential and molecular mechanism of a novel sulfonamide anticancer drug, indisulam (E7070) in combination with CPT-11 for cancer treatment.

Ozawa Y, Kusano K, Owa T, Yokoi A, Asada M, Yoshimatsu K.

Cancer Chemother Pharmacol · journal article · DOI 10.1007/s00280-012-1844-8

Bibliografisk träff 2008-05-29

Population pharmacokinetic and pharmacodynamic analysis to support treatment optimization of combination chemotherapy with indisulam and carboplatin.

Zandvliet AS, Schellens JH, Dittrich C, Wanders J, Beijnen JH, Huitema AD.

Br J Clin Pharmacol · research support, non-u.s. gov't; research-article; evaluation study; journal article · DOI 10.1111/j.1365-2125.2008.03230.x

Bibliografisk träff 2007-02-06

A phase I and pharmacokinetic study of indisulam in combination with carboplatin.

Dittrich C, Zandvliet AS, Gneist M, Huitema AD, King AA, Wanders J.

Br J Cancer · other; research support, non-u.s. gov't; clinical trial, phase i; journal article · DOI 10.1038/sj.bjc.6603606

Bibliografisk träff 2004-01-01

Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.

Abbate F, Casini A, Owa T, Scozzafava A, Supuran CT.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2003.09.062

Bibliografisk träff 2003-02-01

Indisulam: an anticancer sulfonamide in clinical development.

Supuran CT.

Expert Opin Investig Drugs · review; journal article · DOI 10.1517/13543784.12.2.283

Bibliografisk träff 2002-11-01

E7070: a novel synthetic sulfonamide targeting the cell cycle progression for the treatment of cancer.

Van Kesteren C, Beijnen JH, Schellens JH.

Anticancer Drugs · review; journal article · DOI 10.1097/00001813-200211000-00002

Bibliografisk träff 2002-11-01

Development and validation of limited sampling strategies for prediction of the systemic exposure to the novel anticancer agent E7070 (N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide).

van Kesteren C, Mathôt RA, Raymond E, Armand JP, Fumoleau P, Punt C, Ravic M, Wanders J, Beijnen JH, Schellens JH, Early Clinical Studies Group of the EORTC and NDDO Oncology.

Br J Clin Pharmacol · clinical trial, phase ii; clinical trial; research-article; validation study; randomized controlled trial; journal article · DOI 10.1046/j.1365-2125.2002.01684.x

Bibliografisk träff 2002-10-01

Population pharmacokinetics of the novel anticancer agent E7070 during four phase I studies: model building and validation.

Van Kesteren Ch, Mathôt RA, Raymond E, Armand JP, Dittrich Ch, Dumez H, Roché H, Droz JP, Punt C, Ravic M, Wanders J, Beijnen JH, Fumoleau P, Schellens JH, Early Clinical Studies Group of the European Organization for Research and Treatment of Cancer.

J Clin Oncol · journal article · DOI 10.1200/jco.2002.01.005

Bibliografisk träff 2001-11-01

E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo.

Ozawa Y, Sugi NH, Nagasu T, Owa T, Watanabe T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K.

Eur J Cancer · journal article · DOI 10.1016/s0959-8049(01)00275-1