Structural basis for efonidipine block of a voltage-gated Ca<sup>2+</sup> channel.
Xu F, Xiong W, Huang Y, Shen J, Zhou D, Tang L.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2019.03.176 PUBLIKATIONSREGISTRET
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8 träffarEfonidipine, a Ca(2+)-channel blocker, enhances the production of dehydroepiandrosterone sulfate in NCI-H295R human adrenocortical carcinoma cells.
Ikeda K, Saito T, Tojo K.
Tohoku J Exp Med · journal article · DOI 10.1620/tjem.224.263Effects of S(+)-efonidipine on the rabbit sinus node action potential and calcium channel subunits Ca(V)1.2, Ca(V)1.3 and Ca(V)3.1.
Tanaka H, Namekata I, Ogawa T, Tsuneoka Y, Komikado C, Takahara A, Iida-Tanaka N, Izumi-Nakaseko H, Tsuru H, Adachi-Akahane S.
Eur J Pharmacol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2010.09.014T-type Ca2+ channels promote oxygenation-induced closure of the rat ductus arteriosus not only by vasoconstriction but also by neointima formation.
Akaike T, Jin MH, Yokoyama U, Izumi-Nakaseko H, Jiao Q, Iwasaki S, Iwamoto M, Nishimaki S, Sato M, Yokota S, Kamiya Y, Adachi-Akahane S, Ishikawa Y, Minamisawa S.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m109.017061Species difference in the contribution of T-type calcium current to cardiac pacemaking as revealed by r(-)-efonidipine.
Tanaka H, Komikado C, Namekata I, Nakamura H, Suzuki M, Tsuneoka Y, Shigenobu K, Takahara A.
J Pharmacol Sci · comparative study; journal article · DOI 10.1254/jphs.sc0070405A selective T-type Ca2+ channel blocker R(-) efonidipine.
Shin MC, Kim CJ, Min BI, Ogawa S, Tanaka E, Akaike N.
Naunyn Schmiedebergs Arch Pharmacol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1007/s00210-007-0239-6The R(-)-enantiomer of efonidipine blocks T-type but not L-type calcium current in guinea pig ventricular myocardium.
Tanaka H, Komikado C, Shimada H, Takeda K, Namekata I, Kawanishi T, Shigenobu K.
J Pharmacol Sci · journal article · DOI 10.1254/jphs.rcj04001xIdentification of R(-)-isomer of efonidipine as a selective blocker of T-type Ca2+ channels.
Furukawa T, Miura R, Honda M, Kamiya N, Mori Y, Takeshita S, Isshiki T, Nukada T.
Br J Pharmacol · comparative study; research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/sj.bjp.0705944