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Publikationer i urvalet

17 träffar

Bibliografisk träff 2023-04-03

Tilorone increases glucose uptake in vivo and in skeletal muscle cells by enhancing Akt2/AS160 signaling and glucose transporter levels.

Kohler ZM, Trencsenyi G, Juhasz L, Zvara A, Szabo JP, Dux L, Puskas LG, Rovo L, Keller-Pinter A.

J Cell Physiol · research support, non-u.s. gov't; journal article · DOI 10.1002/jcp.30998

Bibliografisk träff 2023-03-24

Transporter Inhibition Profile for the Antivirals Tilorone, Quinacrine and Pyronaridine.

Vignaux PA, Lane TR, Puhl AC, Hau RK, Wright SH, Cherrington NJ, Ekins S.

ACS Omega · research-article; journal article · DOI 10.1021/acsomega.3c00724

Bibliografisk träff 2021-12-31

Tilorone-Dihydrochloride Protects against Rift Valley Fever Virus Infection and Disease in the Mouse Model.

Johnson KN, Kalveram B, Smith JK, Zhang L, Juelich T, Atkins C, Ikegami T, Freiberg AN.

Microorganisms · research-article; journal article · DOI 10.3390/microorganisms10010092

Bibliografisk träff 2021-10-27

Effect of Tilorone on the Dynamics of Viral Load and the Levels of Interferons and Interleukin-1β in the Lung Tissue and Blood Serum of Mice with Experimental Influenza.

Kalyuzhin OV, Isaeva EI, Vetrova EN, Chernysheva AI, Ponezheva LO, Karaulov AV.

Bull Exp Biol Med · research-article; journal article · DOI 10.1007/s10517-021-05306-0

Bibliografisk träff 2021-03-15

Old Drug, New Trick: Tilorone, a Broad-Spectrum Antiviral Drug as a Potential Anti-Fibrotic Therapeutic for the Diseased Heart.

Horlock D, Kaye DM, Winbanks CE, Gao XM, Kiriazis H, Donner DG, Gregorevic P, McMullen JR, Bernardo BC.

Pharmaceuticals (Basel) · research-article; journal article · DOI 10.3390/ph14030263

Bibliografisk träff 2021-01-05

The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase.

Vignaux PA, Minerali E, Lane TR, Foil DH, Madrid PB, Puhl AC, Ekins S.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.chemrestox.0c00466

Bibliografisk träff 2020-04-21

Tilorone, a Broad-Spectrum Antiviral for Emerging Viruses.

Ekins S, Madrid PB.

Antimicrob Agents Chemother · brief-report; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.00440-20

Bibliografisk träff 2020-03-25

Tilorone: a Broad-Spectrum Antiviral Invented in the USA and Commercialized in Russia and beyond.

Ekins S, Lane TR, Madrid PB.

Pharm Res · research-article; journal article · DOI 10.1007/s11095-020-02799-8

Bibliografisk träff 2019-01-01

The effects of coadministration of tilorone dihydrochloride and culture supernatants from <i>Lactobacillus reuteri</i> on the mouse hepatoma cell line.

Alem M, Shahbazfar AA, Zare P, Tayefi-Nasrabadi H.

J Cancer Res Ther · journal article · DOI 10.4103/jcrt.jcrt_41_17

Bibliografisk träff 2018-12-11

Tilorone activates NK cells and cytotoxic lymphocytes that kill HLA-negative tumor cells.

Sharapova TN, Romanova EA, Sashchenko LP, Yashin DV.

IUBMB Life · research support, non-u.s. gov't; journal article · DOI 10.1002/iub.1985

Bibliografisk träff 2018-08-15

Thermodynamics and kinetics of joint action of antiviral agent tilorone and DMSO on model lipid membranes.

Kasian NA, Vashchenko OV, Budianska LV, Brodskii RY, Lisetski LN.

Biochim Biophys Acta Biomembr · journal article · DOI 10.1016/j.bbamem.2018.08.007

Bibliografisk träff 2018-04-12

Pulmonary administration of a dry powder formulation of the antifibrotic drug tilorone reduces silica-induced lung fibrosis in mice.

Vartiainen V, Raula J, Bimbo LM, Viinamäki J, Backman JT, Ugur N, Kauppinen E, Sutinen E, Joensuu E, Koli K, Myllärniemi M.

Int J Pharm · journal article · DOI 10.1016/j.ijpharm.2018.04.019

Bibliografisk träff 2018-01-25

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.

Ekins S, Lingerfelt MA, Comer JE, Freiberg AN, Mirsalis JC, O'Loughlin K, Harutyunyan A, McFarlane C, Green CE, Madrid PB.

Antimicrob Agents Chemother · research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.01711-17

Bibliografisk träff 2013-04-16

Synthesis and activity evaluation of tilorone analogs as potential anticancer agents.

Zhou D, Tuo W, Hu H, Xu J, Chen H, Rao Z, Xiao Y, Hu X, Liu P.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.03.050

Bibliografisk träff 2012-01-08

SAR of α7 nicotinic receptor agonists derived from tilorone: exploration of a novel nicotinic pharmacophore.

Schrimpf MR, Sippy KB, Briggs CA, Anderson DJ, Li T, Ji J, Frost JM, Surowy CS, Bunnelle WH, Gopalakrishnan M, Meyer MD.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2011.12.126

Bibliografisk träff 2007-12-24

alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues.

Briggs CA, Schrimpf MR, Anderson DJ, Gubbins EJ, Grønlien JH, Håkerud M, Ween H, Thorin-Hagene K, Malysz J, Li J, Bunnelle WH, Gopalakrishnan M, Meyer MD.

Br J Pharmacol · other; journal article · DOI 10.1038/sj.bjp.0707649

Bibliografisk träff 2007-06-16

DNA binding of tilorone: 1H NMR and calorimetric studies of the intercalation.

Nishimura T, Okobira T, Kelly AM, Shimada N, Takeda Y, Sakurai K.

Biochemistry · research support, non-u.s. gov't; journal article · DOI 10.1021/bi602402m