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Publikationer i urvalet

8 träffar

Bibliografisk träff 2016-11-07

Design and Synthesis of Cajanine Analogues against Hepatitis C Virus through Down-Regulating Host Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1.

Ji XY, Chen JH, Zheng GH, Huang MH, Zhang L, Yi H, Jin J, Jiang JD, Peng ZG, Li ZR.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.6b01301

Bibliografisk träff 2014-10-13

Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.

Fu J, Tjandra M, Becker C, Bednarczyk D, Capparelli M, Elling R, Hanna I, Fujimoto R, Furegati M, Karur S, Kasprzyk T, Knapp M, Leung K, Li X, Lu P, Mergo W, Miault C, Ng S, Parker D, Peng Y, Roggo S, Rivkin A, Simmons RL, Wang M, Wiedmann B, Weiss AH, Xiao L, Xie L, Xu W, Yifru A, Yang S, Zhou B, Sweeney ZK.

J Med Chem · journal article · DOI 10.1021/jm500862r

Bibliografisk träff 2014-06-03

From chemical tools to clinical medicines: nonimmunosuppressive cyclophilin inhibitors derived from the cyclosporin and sanglifehrin scaffolds.

Sweeney ZK, Fu J, Wiedmann B.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm500223x

Bibliografisk träff 2013-06-10

Cyclophilin inhibitors as antiviral agents.

Peel M, Scribner A.

Bioorg Med Chem Lett · review-article; journal article · DOI 10.1016/j.bmcl.2013.05.101

Bibliografisk träff 2011-04-05

Ranking high affinity ligands of low solubility by NMR spectroscopy.

Landrieu I, Hanoulle X, Fritzinger B, Horvath D, Wieruszeski JM, Lippens G.

ACS Med Chem Lett · brief-report; journal article · DOI 10.1021/ml200039u

Bibliografisk träff 2008-12-22

Debio 025, a cyclophilin binding molecule, is highly efficient in clearing hepatitis C virus (HCV) replicon-containing cells when used alone or in combination with specifically targeted antiviral therapy for HCV (STAT-C) inhibitors.

Coelmont L, Kaptein S, Paeshuyse J, Vliegen I, Dumont JM, Vuagniaux G, Neyts J.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00939-08

Bibliografisk träff 2008-07-14

Comparative in vitro anti-hepatitis C virus activities of a selected series of polymerase, protease, and helicase inhibitors.

Paeshuyse J, Vliegen I, Coelmont L, Leyssen P, Tabarrini O, Herdewijn P, Mittendorfer H, Easmon J, Cecchetti V, Bartenschlager R, Puerstinger G, Neyts J.

Antimicrob Agents Chemother · comparative study; research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01534-07

Bibliografisk träff 2008-01-22

Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent.

Ptak RG, Gallay PA, Jochmans D, Halestrap AP, Ruegg UT, Pallansch LA, Bobardt MD, de Béthune MP, Neyts J, De Clercq E, Dumont JM, Scalfaro P, Besseghir K, Wenger RM, Rosenwirth B.

Antimicrob Agents Chemother · research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.01324-07