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Publikationer i urvalet

20 träffar

Bibliografisk träff 2020-06-02

Ascofuranone suppresses invasion and F-actin cytoskeleton organization in cancer cells by inhibiting the mTOR complex 1 signaling pathway.

Jeong YJ, Hwang SK, Magae J, Chang YC.

Cell Oncol (Dordr) · research-article; journal article · DOI 10.1007/s13402-020-00520-w

Bibliografisk träff 2020-05-18

Ascofuranone inhibits epidermal growth factor-induced cell migration by blocking epithelial-mesenchymal transition in lung cancer cells.

Kim HW, Jeong YJ, Hwang SK, Park YY, Choi YH, Kim CH, Magae J, Chang YC.

Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2020.173199

Bibliografisk träff 2019-04-05

Complete biosynthetic pathways of ascofuranone and ascochlorin in <i>Acremonium egyptiacum</i>.

Araki Y, Awakawa T, Matsuzaki M, Cho R, Matsuda Y, Hoshino S, Shinohara Y, Yamamoto M, Kido Y, Inaoka DK, Nagamune K, Ito K, Abe I, Kita K.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.1819254116

Bibliografisk träff 2017-02-16

Ascofuranone inhibits lipopolysaccharide-induced inflammatory response via NF-kappaB and AP-1, p-ERK, TNF-α, IL-6 and IL-1β in RAW 264.7 macrophages.

Park JY, Chung TW, Jeong YJ, Kwak CH, Ha SH, Kwon KM, Abekura F, Cho SH, Lee YC, Ha KT, Magae J, Chang YC, Kim CH.

PLoS One · research-article; journal article · DOI 10.1371/journal.pone.0171322

Bibliografisk träff 2016-11-02

Re-identification of the ascofuranone-producing fungus Ascochyta viciae as Acremonium sclerotigenum.

Hijikawa Y, Matsuzaki M, Suzuki S, Inaoka DK, Tatsumi R, Kido Y, Kita K.

J Antibiot (Tokyo) · research support, non-u.s. gov't; journal article · DOI 10.1038/ja.2016.132

Bibliografisk träff 2013-10-03

Ascofuranone suppresses EGF-induced HIF-1α protein synthesis by inhibition of the Akt/mTOR/p70S6K pathway in MDA-MB-231 breast cancer cells.

Jeong YJ, Cho HJ, Magae J, Lee IK, Park KG, Chang YC.

Toxicol Appl Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.taap.2013.09.027

Bibliografisk träff 2012-11-23

Pharmacophore identification of ascofuranone, potent inhibitor of cyanide-insensitive alternative oxidase of Trypanosoma brucei.

Saimoto H, Kido Y, Haga Y, Sakamoto K, Kita K.

J Biochem · research support, non-u.s. gov't; journal article · DOI 10.1093/jb/mvs135

Bibliografisk träff 2012-05-09

Ascofuranone stimulates expression of adiponectin and peroxisome proliferator activated receptor through the modulation of mitogen activated protein kinase family members in 3T3-L1, murine pre-adipocyte cell line.

Chang YC, Cho HJ.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2012.05.008

Bibliografisk träff 2010-10-26

Ascofuranone: a possible therapeutic tool for autosomal dominant polycystic kidney disease?

Cardinale V, Alvaro D.

Mol Cancer Ther · letter; comment · DOI 10.1158/1535-7163.mct-10-0741

Bibliografisk träff 2010-06-29

p53-independent induction of G1 arrest and p21WAF1/CIP1 expression by ascofuranone, an isoprenoid antibiotic, through downregulation of c-Myc.

Jeong JH, Kang SS, Park KK, Chang HW, Magae J, Chang YC.

Mol Cancer Ther · research support, non-u.s. gov't; journal article · DOI 10.1158/1535-7163.mct-09-1159

Bibliografisk träff 2010-05-09

Ascofuranone prevents ER stress-induced insulin resistance via activation of AMP-activated protein kinase in L6 myotube cells.

Hwang SL, Chang HW, Lee IK, Yang BK, Magae J, Chang YC.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2010.05.034

Bibliografisk träff 2009-05-01

Suppression of PAI-1 expression through inhibition of the EGFR-mediated signaling cascade in rat kidney fibroblast by ascofuranone.

Cho HJ, Kang JH, Kim T, Park KK, Kim CH, Lee IS, Min KS, Magae J, Nakajima H, Bae YS, Chang YC.

J Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1002/jcb.22130

Bibliografisk träff 2006-11-17

Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms.

Cho HJ, Kang JH, Kwak JY, Lee TS, Lee IS, Park NG, Nakajima H, Magae J, Chang YC.

Carcinogenesis · research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/bgl217

Bibliografisk träff 2005-11-09

Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol.

Yabu Y, Suzuki T, Nihei C, Minagawa N, Hosokawa T, Nagai K, Kita K, Ohta N.

Parasitol Int · research support, non-u.s. gov't; journal article · DOI 10.1016/j.parint.2005.09.003

Bibliografisk träff 2003-06-01

The efficacy of ascofuranone in a consecutive treatment on Trypanosoma brucei brucei in mice.

Yabu Y, Yoshida A, Suzuki T, Nihei C, Kawai K, Minagawa N, Hosokawa T, Nagai K, Kita K, Ohta N.

Parasitol Int · research support, non-u.s. gov't; journal article · DOI 10.1016/s1383-5769(03)00012-6

Bibliografisk träff 1999-01-01

[Hypolipidemic action of ascofuranone in hepatoblastoma G2 cell culture].

Trenin AS.

Antibiot Khimioter · journal article

Bibliografisk träff 1997-02-01

An antibiotic, ascofuranone, specifically inhibits respiration and in vitro growth of long slender bloodstream forms of Trypanosoma brucei brucei.

Minagawa N, Yabu Y, Kita K, Nagai K, Ohta N, Meguro K, Sakajo S, Yoshimoto A.

Mol Biochem Parasitol · research support, non-u.s. gov't; corrected and republished article; journal article · DOI 10.1016/s0166-6851(96)02797-1

Bibliografisk träff 1996-10-01

An antibiotic, ascofuranone, specifically inhibits respiration and in vitro growth of long slender bloodstream forms of Trypanosoma brucei brucei.

Minagawa N, Yabu Y, Kita K, Nagai K, Ohta N, Meguro K, Sakajo S, Yoshimoto A.

Mol Biochem Parasitol · research support, non-u.s. gov't; journal article · DOI 10.1016/0166-6851(96)02665-5

Bibliografisk träff 1988-07-01

Antitumor and antimetastatic activity of an antibiotic, ascofuranone, and activation of phagocytes.

Magae J, Hayasaki J, Matsuda Y, Hotta M, Hosokawa T, Suzuki S, Nagai K, Ando K, Tamura G.

J Antibiot (Tokyo) · research support, non-u.s. gov't; journal article · DOI 10.7164/antibiotics.41.959

Bibliografisk träff 1973-11-01

Isolation and structure of ascofuranone and ascofranol, antibiotics with hypolipidemic activity.

Sasaki H, Hosokawa T, Sawada M, Ando K.

J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.26.676