Ascochlorin induces caspase-independent necroptosis in LPS-stimulated RAW 264.7 macrophages.
Park J, Kim HD, Lee SH, Kwak CH, Chang YC, Lee YC, Chung TW, Magae J, Kim CH.
J Ethnopharmacol · journal article · DOI 10.1016/j.jep.2019.111898 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
14 träffarComplete biosynthetic pathways of ascofuranone and ascochlorin in <i>Acremonium egyptiacum</i>.
Araki Y, Awakawa T, Matsuzaki M, Cho R, Matsuda Y, Hoshino S, Shinohara Y, Yamamoto M, Kido Y, Inaoka DK, Nagamune K, Ito K, Abe I, Kita K.
Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.1819254116Multidomain P450 Epoxidase and a Terpene Cyclase from the Ascochlorin Biosynthetic Pathway in Fusarium sp.
Quan Z, Awakawa T, Wang D, Hu Y, Abe I.
Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.orglett.9b00616Suppression of c-Myc enhances p21<sup>WAF1/CIP1</sup> -mediated G1 cell cycle arrest through the modulation of ERK phosphorylation by ascochlorin.
Jeong YJ, Hoe HS, Cho HJ, Park KK, Kim DD, Kim CH, Magae J, Kang DW, Lee SR, Chang YC.
J Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1002/jcb.26366Ascochlorin Suppresses MMP-2-Mediated Migration and Invasion by Targeting FAK and JAK-STAT Signaling Cascades.
Cho HJ, Park JH, Nam JH, Chang YC, Park B, Hoe HS.
J Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1002/jcb.26179Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy.
Min-Wen JC, Yan-Jiang BC, Mishra S, Dai X, Magae J, Shyh-Chang N, Kumar AP, Sethi G.
Adv Protein Chem Struct Biol · research support, non-u.s. gov't; review; journal article · DOI 10.1016/bs.apcsb.2017.01.001Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.
Dai X, Ahn KS, Kim C, Siveen KS, Ong TH, Shanmugam MK, Li F, Shi J, Kumar AP, Wang LZ, Goh BC, Magae J, Hui KM, Sethi G.
Mol Oncol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.molonc.2014.12.008Ascochlorin inhibits growth factor-induced HIF-1α activation and tumor-angiogenesis through the suppression of EGFR/ERK/p70S6K signaling pathway in human cervical carcinoma cells.
Jeong JH, Jeong YJ, Cho HJ, Shin JM, Kang JH, Park KK, Park YY, Chung IK, Chang HW, Magae J.
J Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1002/jcb.24001Ascochlorin suppresses TGF-β1-induced PAI-1 expression through the inhibition of phospho-EGFR in rat kidney fibroblast cells.
Cho HJ, Kang JH, Jeong JH, Jeong YJ, Park KK, Park YY, Moon YS, Kim HT, Chung IK, Kim CH, Chang HW, Chang YC.
Mol Biol Rep · research support, non-u.s. gov't; journal article · DOI 10.1007/s11033-011-1251-yAscochlorin, an isoprenoid antibiotic, induces G1 arrest via downregulation of c-Myc in a p53-independent manner.
Jeong JH, Chang YC.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2010.06.037Ascochlorin is a novel, specific inhibitor of the mitochondrial cytochrome bc1 complex.
Berry EA, Huang LS, Lee DW, Daldal F, Nagai K, Minagawa N.
Biochim Biophys Acta · comparative study; research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bbabio.2009.12.003Ascochlorin activates p53 in a manner distinct from DNA damaging agents.
Jeong JH, Nakajima H, Magae J, Furukawa C, Taki K, Otsuka K, Tomita M, Lee IS, Kim CH, Chang HW, Min KS, Park KK, Park KK, Chang YC.
Int J Cancer · research support, non-u.s. gov't; journal article · DOI 10.1002/ijc.24259Pseudodestruxins A and B: new cyclic depsipeptides from the coprophilous fungus Nigrosabulum globosum.
Che Y, Swenson DC, Gloer JB, Koster B, Malloch D.
J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np000547rTotal synthesis of (-)-ascochlorin via a cyclobutenone-based benzannulation strategy.
Dudley GB, Takaki KS, Cha DD, Danheiser RL.
Org Lett · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/ol006561c