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Publikationer i urvalet

16 träffar

Bibliografisk träff 2020-06-22

Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.

Wang C, Li Y, Yan S, Wang H, Shao X, Xiao M, Yang B, Qin G, Kong R, Chen R, Zhang N.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-020-16966-3

Bibliografisk träff 2016-03-16

FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell.

Chen Y, Xie X, Li X, Wang P, Jing Q, Yue J, Liu Y, Cheng Z, Li J, Song H, Li G, Liu R, Wang J.

Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2016.03.017

Bibliografisk träff 2014-04-09

Canine and human sarcomas exhibit predominant FGFR1 expression and impaired viability after inhibition of signaling.

Schweiger N, Hauck M, Steinhoff H, Sampl S, Reifinger M, Walter I, Kreilmeier T, Marian B, Grusch M, Berger W, Holzmann K, Kleiter M.

Mol Carcinog · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1002/mc.22155

Bibliografisk träff 2012-11-21

SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.

Murayama N, Kadoshima T, Takemoto N, Kodama S, Toba T, Ogino R, Noshita T, Oka T, Ueno S, Kuroda M, Shimmyo Y, Morita Y, Inoue T.

ACS Chem Neurosci · research-article; journal article · DOI 10.1021/cn300183k

Bibliografisk träff 2012-08-02

6-Arylpyrido[2,3-d]pyrimidines as novel ATP-competitive inhibitors of bacterial D-alanine:D-alanine ligase.

Škedelj V, Arsovska E, Tomašić T, Kroflič A, Hodnik V, Hrast M, Bešter-Rogač M, Anderluh G, Gobec S, Bostock J, Chopra I, O'Neill AJ, Randall C, Zega A.

PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0039922

Bibliografisk träff 2011-09-28

Functional upregulation of system xc- by fibroblast growth factor-2.

Liu X, Resch J, Rush T, Lobner D.

Neuropharmacology · journal article · DOI 10.1016/j.neuropharm.2011.09.019

Bibliografisk träff 2009-12-11

The synthetic inhibitor of fibroblast growth factor receptor PD166866 controls negatively the growth of tumor cells in culture.

Risuleo G, Ciacciarelli M, Castelli M, Galati G.

J Exp Clin Cancer Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1756-9966-28-151

Bibliografisk träff 2007-10-13

2D Autocorrelation, CoMFA, and CoMSIA modeling of protein tyrosine kinases' inhibition by substituted pyrido[2,3-d]pyrimidine derivatives.

Caballero J, Fernández M, Saavedra M, González-Nilo FD.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.10.024

Bibliografisk träff 2007-09-01

Reduction of cell proliferation induced by PD166866: an inhibitor of the basic fibroblast growth factor.

Calandrella N, Risuleo G, Scarsella G, Mustazza C, Castelli M, Galati F, Giuliani A, Galati G.

J Exp Clin Cancer Res · research support, non-u.s. gov't; journal article

Bibliografisk träff 2005-04-01

Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis.

Cassina P, Pehar M, Vargas MR, Castellanos R, Barbeito AG, Estévez AG, Thompson JA, Beckman JS, Barbeito L.

J Neurochem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1111/j.1471-4159.2004.02984.x

Bibliografisk träff 2005-04-01

Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1.

Palmer BD, Smaill JB, Rewcastle GW, Dobrusin EM, Kraker A, Moore CW, Steinkampf RW, Denny WA.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2005.01.079

Bibliografisk träff 2003-06-12

Thyroid hormone activates fibroblast growth factor receptor-1 in bone.

Stevens DA, Harvey CB, Scott AJ, O'Shea PJ, Barnard JC, Williams AJ, Brady G, Samarut J, Chassande O, Williams GR.

Mol Endocrinol · research support, non-u.s. gov't; journal article · DOI 10.1210/me.2003-0137

Bibliografisk träff 2001-07-01

Tyrosine kinase receptor activation inhibits NPR-C in lung arterial smooth muscle cells.

Sun JZ, Oparil S, Lucchesi P, Thompson JA, Chen YF.

Am J Physiol Lung Cell Mol Physiol · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1152/ajplung.2001.281.1.l155

Bibliografisk träff 2001-06-01

Soluble 2-substituted aminopyrido[2,3-d]pyrimidin-7-yl ureas. Structure-activity relationships against selected tyrosine kinases and exploration of in vitro and in vivo anticancer activity.

Schroeder MC, Hamby JM, Connolly CJ, Grohar PJ, Winters RT, Barvian MR, Moore CW, Boushelle SL, Crean SM, Kraker AJ, Driscoll DL, Vincent PW, Elliott WL, Lu GH, Batley BL, Dahring TK, Major TC, Panek RL, Doherty AM, Showalter HD.

J Med Chem · journal article · DOI 10.1021/jm0004291

Bibliografisk träff 2000-11-01

3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and related 2-urea derivatives are potent and selective inhibitors of the FGF receptor-1 tyrosine kinase.

Thompson AM, Connolly CJ, Hamby JM, Boushelle S, Hartl BG, Amar AM, Kraker AJ, Driscoll DL, Steinkampf RW, Patmore SJ, Vincent PW, Roberts BJ, Elliott WL, Klohs W, Leopold WR, Showalter HD, Denny WA.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm000161d

Bibliografisk träff 1998-07-01

In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase.

Panek RL, Lu GH, Dahring TK, Batley BL, Connolly C, Hamby JM, Brown KJ.

J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(24)37619-0