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Publikationer i urvalet

12 träffar

Bibliografisk träff 2019-12-09

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.

Ross NT, Lohmann F, Carbonneau S, Fazal A, Weihofen WA, Gleim S, Salcius M, Sigoillot F, Henault M, Carl SH, Rodríguez-Molina JB, Miller HR, Brittain SM, Murphy J, Zambrowski M, Boynton G, Wang Y, Chen A, Molind GJ, Wilbertz JH, Artus-Revel CG, Jia M, Akinjiyan FA, Turner J, Knehr J, Carbone W, Schuierer S, Reece-Hoyes JS, Xie K, Saran C, Williams ET, Roma G, Spencer M, Jenkins J, George EL, Thomas JR, Michaud G, Schirle M, Tallarico J, Passmore LA, Chao JA, Beckwith REJ.

Nat Chem Biol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41589-019-0424-1

Bibliografisk träff 2019-08-06

JTE-607, a multiple cytokine production inhibitor, targets CPSF3 and inhibits pre-mRNA processing.

Kakegawa J, Sakane N, Suzuki K, Yoshida T.

Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2019.08.004

Bibliografisk träff 2011-08-03

Effects of a cytokine inhibitor, JTE-607, on the response to endotoxin in healthy human volunteers.

Borozdenkova S, Mant TG, Allen E, Pu K, Hoshino S, Jurcevic S.

Int Immunopharmacol · research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1016/j.intimp.2011.07.013

Bibliografisk träff 2009-11-18

JTE-607, a multiple cytokine production inhibitor, induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.

Tajima N, Fukui K, Uesato N, Maruhashi J, Yoshida T, Watanabe Y, Tojo A.

Cancer Sci · research-article; journal article · DOI 10.1111/j.1349-7006.2009.01446.x

Bibliografisk träff 2008-07-01

JTE-607, an inflammatory cytokine synthesis inhibitor, attenuates ischemia/reperfusion-induced renal injury by reducing neutrophil activation in rats.

Asaga T, Ueki M, Chujo K, Taie S.

J Biosci Bioeng · journal article · DOI 10.1263/jbb.106.22

Bibliografisk träff 2006-10-01

JTE-607, a multiple cytokine production inhibitor, ameliorates disease in a SCID mouse xenograft acute myeloid leukemia model.

Uesato N, Fukui K, Maruhashi J, Tojo A, Tajima N.

Exp Hematol · journal article · DOI 10.1016/j.exphem.2006.05.016

Bibliografisk träff 2004-07-27

Comparative study of glucocorticoids, cyclosporine A, and JTE-607 [(-)-Ethyl-N[3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]-L-phenylalaninate dihydrochloride] in a mouse septic shock model.

Iwamura H, Sato M, Wakitani K.

J Pharmacol Exp Ther · comparative study; journal article · DOI 10.1124/jpet.104.072421

Bibliografisk träff 2004-06-01

Pharmacologic preconditioning of JTE-607, a novel cytokine inhibitor, attenuates ischemia-reperfusion injury in the myocardium.

Ryugo M, Sawa Y, Ono M, Miyamoto Y, Aleshin AN, Matsuda H.

J Thorac Cardiovasc Surg · comparative study; journal article · DOI 10.1016/j.jtcvs.2003.08.015

Bibliografisk träff 2004-03-01

JTE-607, a cytokine release blocker, attenuates acid aspiration-induced lung injury in rats.

Jian MY, Koizumi T, Tsushima K, Kubo K.

Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2004.02.026

Bibliografisk träff 2002-09-27

Prior burn insult induces lethal acute lung injury in endotoxemic mice: effects of cytokine inhibition.

Sasaki J, Fujishima S, Iwamura H, Wakitani K, Aiso S, Aikawa N.

Am J Physiol Lung Cell Mol Physiol · journal article · DOI 10.1152/ajplung.00108.2002

Bibliografisk träff 2002-03-01

Prophylactic effect of JTE-607 on LPS-induced acute lung injury in rats with CINC-1 inhibition.

Iwamura H, Inushima K, Takeuchi K, Kakutani M, Wakitani K.

Inflamm Res · journal article · DOI 10.1007/pl00000288

Bibliografisk träff 1999-08-01

JTE-607, a novel inflammatory cytokine synthesis inhibitor without immunosuppression, protects from endotoxin shock in mice.

Kakutani M, Takeuchi K, Waga I, Iwamura H, Wakitani K.

Inflamm Res · journal article · DOI 10.1007/s000110050487