Dual Analysis of N-methyl-2-pyridone-5-carboxamide and N-1-methylnicotinamide in Urine by HPLC with UV Detection.
Nguyen VL, Saldanha R, Fitzpatrick M.
J Chromatogr Sci · journal article · DOI 10.1093/chromsci/bmaa134 PUBLIKATIONSREGISTRET
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26 träffar1-Methylnicotinamide is an immune regulatory metabolite in human ovarian cancer.
Kilgour MK, MacPherson S, Zacharias LG, Ellis AE, Sheldon RD, Liu EY, Keyes S, Pauly B, Carleton G, Allard B, Smazynski J, Williams KS, Watson PH, Stagg J, Nelson BH, DeBerardinis RJ, Jones RG, Hamilton PT, Lum JJ.
Sci Adv · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1126/sciadv.abe1174Analysis of urinary exosomal metabolites identifies cardiovascular risk signatures with added value to urine analysis.
Agudiez M, Martinez PJ, Martin-Lorenzo M, Heredero A, Santiago-Hernandez A, Molero D, Garcia-Segura JM, Aldamiz-Echevarria G, Alvarez-Llamas G.
BMC Biol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s12915-020-00924-yCrystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide.
Swaminathan S, Birudukota S, Thakur MK, Parveen R, Kandan S, Juluri S, Shaik S, Anand NN, Burri RR, Kristam R, Hallur MS, Rajagopal S, Schreuder H, Langer T, Rudolph C, Ruf S, Dhakshinamoorthy S, Gosu R, Kannt A.
Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2017.07.087Functional and Biochemical Endothelial Profiling <i>In Vivo</i> in a Murine Model of Endothelial Dysfunction; Comparison of Effects of 1-Methylnicotinamide and Angiotensin-converting Enzyme Inhibitor.
Bar A, Olkowicz M, Tyrankiewicz U, Kus E, Jasinski K, Smolenski RT, Skorka T, Chlopicki S.
Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2017.00183Effects of 1-Methylnicotinamide (MNA) on Exercise Capacity and Endothelial Response in Diabetic Mice.
Przyborowski K, Wojewoda M, Sitek B, Zakrzewska A, Kij A, Wandzel K, Zoladz JA, Chlopicki S.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0130908Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese.
Liu M, Li L, Chu J, Zhu B, Zhang Q, Yin X, Jiang W, Dai G, Ju W, Wang Z, Yang Q, Fang Z.
J Clin Endocrinol Metab · research support, non-u.s. gov't; research-article; journal article · DOI 10.1210/jc.2015-1732N(1)-methylnicotinamide as an endogenous probe for drug interactions by renal cation transporters: studies on the metformin-trimethoprim interaction.
Müller F, Pontones CA, Renner B, Mieth M, Hoier E, Auge D, Maas R, Zolk O, Fromm MF.
Eur J Clin Pharmacol · randomized controlled trial; journal article · DOI 10.1007/s00228-014-1770-2Simultaneous determination of N(1)-methylnicotinamide, L-carnitine, and creatinine in human plasma and urine by liquid chromatography with mass spectrometry for assessing the activities of multiple renal cationic transporters.
Nobuoka Y, Ogawa R, Echizen H.
J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/j.jchromb.2014.07.034SPE-NMR metabolite sub-profiling of urine.
Jacobs DM, Spiesser L, Garnier M, de Roo N, van Dorsten F, Hollebrands B, van Velzen E, Draijer R, van Duynhoven J.
Anal Bioanal Chem · journal article · DOI 10.1007/s00216-012-6339-2Annotation of the human adult urinary metabolome and metabolite identification using ultra high performance liquid chromatography coupled to a linear quadrupole ion trap-Orbitrap mass spectrometer.
Roux A, Xu Y, Heilier JF, Olivier MF, Ezan E, Tabet JC, Junot C.
Anal Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/ac300829fAnti-diabetic effects of 1-methylnicotinamide (MNA) in streptozocin-induced diabetes in rats.
Watała C, Kaźmierczak P, Dobaczewski M, Przygodzki T, Bartuś M, Łomnicka M, Słomińska EM, Durackova Z, Chłopicki S.
Pharmacol Rep · research support, non-u.s. gov't; journal article · DOI 10.1016/s1734-1140(09)70010-6Matrix metaloproteinases activity during the evolution of hypoxic-ischemic brain damage in the immature rat. The effect of 1-methylnicotinamide (MNA).
Dragun P, Makarewicz D, Wójcik L, Ziemka-Nałecz M, Słomka M, Zalewska T.
J Physiol Pharmacol · research support, non-u.s. gov't; journal article1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophages.
Biedroń R, Ciszek M, Tokarczyk M, Bobek M, Kurnyta M, Słominska EM, Smoleński RT, Marcinkiewicz J.
Arch Immunol Ther Exp (Warsz) · research support, non-u.s. gov't; research-article; journal article · DOI 10.1007/s00005-008-0009-21-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells.
Kuykendall JR, Cox R, Kinder D.
Toxicol In Vitro · research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.tiv.2007.05.0171-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway.
Chlopicki S, Swies J, Mogielnicki A, Buczko W, Bartus M, Lomnicka M, Adamus J, Gebicki J.
Br J Pharmacol · other; research support, non-u.s. gov't; journal article · DOI 10.1038/sj.bjp.0707383Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study.
Wozniacka A, Wieczorkowska M, Gebicki J, Sysa-Jedrzejowska A.
Clin Exp Dermatol · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1365-2230.2005.01908.xChemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection.
Ohdoi C, Nyhan WL, Kuhara T.
J Chromatogr B Analyt Technol Biomed Life Sci · journal article · DOI 10.1016/s1570-0232(03)00277-01-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin.
Gebicki J, Sysa-Jedrzejowska A, Adamus J, Woźniacka A, Rybak M, Zielonka J.
Pol J Pharmacol · comparative study; research support, non-u.s. gov't; journal articleAccumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure.
Slominska EM, Smolenski RT, Szolkiewicz M, Leaver N, Rutkowski B, Simmonds HA, Swierczynski J.
Mol Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1023/a:1014445329756Validation of an HPLC method for the determination of urinary and plasma levels of N1-methylnicotinamide, an endogenous marker of renal cationic transport and plasma flow.
Musfeld C, Biollaz J, Bélaz N, Kesselring UW, Decosterd LA.
J Pharm Biomed Anal · validation study; journal article · DOI 10.1016/s0731-7085(00)00425-8Renal clearance of N(1)-methylnicotinamide: a sensitive marker of the severity of liver dysfunction in cirrhosis.
Orlando R, Floreani M, Napoli E, Padrini R, Palatini P.
Nephron · research support, non-u.s. gov't; journal article · DOI 10.1159/000045536Quantitation of urinary niacin metabolites by reversed-phase liquid chromatography.
Carter EG.
Am J Clin Nutr · comparative study; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1093/ajcn/36.5.926Excretion of tryptophan-niacin metabolites by young men: effects of tryptophan, leucine, and vitamin B6 intakes.
Patterson JI, Brown RR, Linkswiler H, Harper AE.
Am J Clin Nutr · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1093/ajcn/33.10.2157Direct urinary assay method for N1-methylnicotinamide by soap chromatography.
Shaikh B, Pontzer NJ.
J Chromatogr · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/s0378-4347(00)81840-xAutomated and manual determination of N1-methylnicotinamide in urine.
Pelletier O, Brassard R.
Am J Clin Nutr · comparative study; journal article · DOI 10.1093/ajcn/30.12.2108