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Publikationer i urvalet

9 träffar

Bibliografisk träff 2024-06-22

2'-β-Methylselenyl nucleos(t)ide analogs as reverse transcriptase inhibitors against diverse HIV mutants.

Yoshida Y, Niimi Y, Fushihara D, Katakura H, Fukui R, Murase H, Tomoike F, Hashiya F, Murakami T, Kodama EN, Suzuki T, Yasukawa K, Kimura Y, Abe H.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2024.117813

Bibliografisk träff 2019-02-07

Discovery of a Series of 2'-α-Fluoro,2'-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus.

Mengshetti S, Zhou L, Sari O, De Schutter C, Zhang H, Cho JH, Tao S, Bassit LC, Verma K, Domaoal RA, Ehteshami M, Jiang Y, Ovadia R, Kasthuri M, Ollinger Russell O, McBrayer T, Whitaker T, Pattassery J, Pascual ML, Uher L, Lin BY, Lee S, Amblard F, Coats SJ, Schinazi RF.

J Med Chem · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.8b01300

Bibliografisk träff 2016-08-03

A fluorescence polarization based assay for the identification and characterization of polymerase inhibitors.

Nasiri HR, Kiss L, Krämer J.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2016.08.003

Bibliografisk träff 2009-07-13

Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.

Sluis-Cremer N, Koontz D, Bassit L, Hernandez-Santiago BI, Detorio M, Rapp KL, Amblard F, Bondada L, Grier J, Coats SJ, Schinazi RF, Mellors JW.

Antimicrob Agents Chemother · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.00392-09

Bibliografisk träff 2007-06-04

Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine.

Nakata H, Amano M, Koh Y, Kodama E, Yang G, Bailey CM, Kohgo S, Hayakawa H, Matsuoka M, Anderson KS, Cheng YC, Mitsuya H.

Antimicrob Agents Chemother · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1128/aac.00277-07

Bibliografisk träff 2007-05-21

Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir.

Marchand B, White KL, Ly JK, Margot NA, Wang R, McDermott M, Miller MD, Götte M.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.00314-07

Bibliografisk träff 2005-04-01

Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.

Boyle NA, Rajwanshi VK, Prhavc M, Wang G, Fagan P, Chen F, Ewing GJ, Brooks JL, Hurd T, Leeds JM, Bruice TW, Cook PD.

J Med Chem · journal article · DOI 10.1021/jm040101y

Bibliografisk träff 2003-10-01

Inhibition of human immunodeficiency virus reverse transcriptase by synadenol triphosphate and its E-isomer.

Wang R, Harada S, Mitsuya H, Zemlicka J.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm030048y

Bibliografisk träff 1994-10-01

Synthesis and evaluation of the anti-HIV activity of aza and deaza analogues of isoddA and their phosphates as prodrugs.

Franchetti P, Cappellacci L, Grifantini M, Messini L, abu Sheikha G, Loi AG, Tramontano E, de Montis A, Spiga MG, La Colla P.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00047a011