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Publikationer i urvalet

22 träffar

Bibliografisk träff 2020-10-01

Association Between L-OPA1 Cleavage and Cardiac Dysfunction During Ischemia-Reperfusion Injury in Rats.

Rodríguez-Graciani KM, Chapa-Dubocq XR, MacMillan-Crow LA, Javadov S.

Cell Physiol Biochem · research-article; journal article · DOI 10.33594/000000303

Bibliografisk träff 2020-08-14

XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia-reperfusion injury.

Zhao Z, Wu J, Xu H, Zhou C, Han B, Zhu H, Hu Z, Ma Z, Ming Z, Yao Y, Zeng R, Xu G.

Cell Death Dis · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41419-020-02871-6

Bibliografisk träff 2019-08-01

Mitochondrial-Targeted Antioxidants Attenuate TGF-β2 Signaling in Human Trabecular Meshwork Cells.

Rao VR, Lautz JD, Kaja S, Foecking EM, Lukács E, Stubbs EB.

Invest Ophthalmol Vis Sci · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1167/iovs.19-27542

Bibliografisk träff 2019-03-01

Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers.

Seminotti B, Leipnitz G, Karunanidhi A, Kochersperger C, Roginskaya VY, Basu S, Wang Y, Wipf P, Van Houten B, Mohsen AW, Vockley J.

Hum Mol Genet · research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/hmg/ddy403

Bibliografisk träff 2018-04-13

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.

Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ.

Redox Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.redox.2018.04.007

Bibliografisk träff 2018-04-09

XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent.

Polyzos AA, Wood NI, Williams P, Wipf P, Morton AJ, McMurray CT.

PLoS One · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pone.0194580

Bibliografisk träff 2017-01-01

Effectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation Mitigators.

Epperly MW, Sacher JR, Krainz T, Zhang X, Wipf P, Liang M, Fisher R, Li S, Wang H, Greenberger JS.

In Vivo · research-article; journal article · DOI 10.21873/invivo.11022

Bibliografisk träff 2016-11-11

Elucidating Mitochondrial Electron Transport Chain Supercomplexes in the Heart During Ischemia-Reperfusion.

Jang S, Lewis TS, Powers C, Khuchua Z, Baines CP, Wipf P, Javadov S.

Antioxid Redox Signal · research-article; journal article · DOI 10.1089/ars.2016.6635

Bibliografisk träff 2016-09-07

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis.

Krainz T, Gaschler MM, Lim C, Sacher JR, Stockwell BR, Wipf P.

ACS Cent Sci · research-article; journal article · DOI 10.1021/acscentsci.6b00199

Bibliografisk träff 2016-02-21

Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes.

Polyzos A, Holt A, Brown C, Cosme C, Wipf P, Gomez-Marin A, Castro MR, Ayala-Peña S, McMurray CT.

Hum Mol Genet · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/hmg/ddw051

Bibliografisk träff 2015-11-01

Mitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged rats.

Javadov S, Jang S, Rodriguez-Reyes N, Rodriguez-Zayas AE, Soto Hernandez J, Krainz T, Wipf P, Frontera W.

Oncotarget · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.18632/oncotarget.5783

Bibliografisk träff 2015-08-06

Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington's Disease.

Budworth H, Harris FR, Williams P, Lee DY, Holt A, Pahnke J, Szczesny B, Acevedo-Torres K, Ayala-Peña S, McMurray CT.

PLoS Genet · research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pgen.1005267

Bibliografisk träff 2014-10-23

Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats.

Escobales N, Nuñez RE, Jang S, Parodi-Rullan R, Ayala-Peña S, Sacher JR, Skoda EM, Wipf P, Frontera W, Javadov S.

J Mol Cell Cardiol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.yjmcc.2014.10.009

Bibliografisk träff 2013-08-20

Pharmacological mitigation of tissue damage during brain microdialysis.

Nesbitt KM, Jaquins-Gerstl A, Skoda EM, Wipf P, Michael AC.

Anal Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/ac401201x

Bibliografisk träff 2013-08-07

Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells.

Goff JP, Shields DS, Wang H, Skoda EM, Sprachman MM, Wipf P, Garapati VK, Atkinson J, London B, Lazo JS, Kagan V, Epperly MW, Greenberger JS.

Exp Hematol · research-article; evaluation study; journal article; research support, n.i.h., extramural · DOI 10.1016/j.exphem.2013.08.001

Bibliografisk träff 2013-02-06

Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration.

Nasto LA, Robinson AR, Ngo K, Clauson CL, Dong Q, St Croix C, Sowa G, Pola E, Robbins PD, Kang J, Niedernhofer LJ, Wipf P, Vo NV.

J Orthop Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/jor.22320

Bibliografisk träff 2012-11-01

Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease.

Xun Z, Rivera-Sánchez S, Ayala-Peña S, Lim J, Budworth H, Skoda EM, Robbins PD, Niedernhofer LJ, Wipf P, McMurray CT.

Cell Rep · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.celrep.2012.10.001

Bibliografisk träff 2012-01-01

Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres.

Skoda EM, Davis GC, Wipf P.

Org Process Res Dev · research-article; journal article · DOI 10.1021/op2002613

Bibliografisk träff 2010-04-23

Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation.

Tyurina YY, Tyurin VA, Kaynar AM, Kapralova VI, Wasserloos K, Li J, Mosher M, Wright L, Wipf P, Watkins S, Pitt BR, Kagan VE.

Am J Physiol Lung Cell Mol Physiol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1152/ajplung.00035.2010

Bibliografisk träff 2007-09-01

Hemigramicidin-TEMPO conjugates: novel mitochondria-targeted antioxidants.

Fink MP, Macias CA, Xiao J, Tyurina YY, Delude RL, Greenberger JS, Kagan VE, Wipf P.

Crit Care Med · review; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1097/01.ccm.0000279192.96303.e7

Bibliografisk träff 2007-05-29

Hemigramicidin-TEMPO conjugates: novel mitochondria-targeted anti-oxidants.

Fink MP, Macias CA, Xiao J, Tyurina YY, Jiang J, Belikova N, Delude RL, Greenberger JS, Kagan VE, Wipf P.

Biochem Pharmacol · review; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bcp.2007.05.019

Bibliografisk träff 2007-02-01

Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock.

Macias CA, Chiao JW, Xiao J, Arora DS, Tyurina YY, Delude RL, Wipf P, Kagan VE, Fink MP.

Ann Surg · research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1097/01.sla.0000236626.57752.8e