Baicalein inhibits RLS3-induced ferroptosis in melanocytes.
Yang M, Li X, Li H, Zhang X, Liu X, Song Y.
Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2021.05.010 PUBLIKATIONSREGISTRET
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28 träffarGSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis.
Wang Q, Bin C, Xue Q, Gao Q, Huang A, Wang K, Tang N.
Cell Death Dis · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41419-021-03718-4H-ferritin suppression and pronounced mitochondrial respiration make Hepatocellular Carcinoma cells sensitive to RSL3-induced ferroptosis.
Asperti M, Bellini S, Grillo E, Gryzik M, Cantamessa L, Ronca R, Maccarinelli F, Salvi A, De Petro G, Arosio P, Mitola S, Poli M.
Free Radic Biol Med · research support, non-u.s. gov't; journal article · DOI 10.1016/j.freeradbiomed.2021.04.024O-GlcNAcylation enhances sensitivity to RSL3-induced ferroptosis via the YAP/TFRC pathway in liver cancer.
Zhu G, Murshed A, Li H, Ma J, Zhen N, Ding M, Zhu J, Mao S, Tang X, Liu L, Sun F, Jin L, Pan Q.
Cell Death Discov · research-article; journal article · DOI 10.1038/s41420-021-00468-2Cytoglobin promotes sensitivity to ferroptosis by regulating p53-YAP1 axis in colon cancer cells.
Ye S, Xu M, Zhu T, Chen J, Shi S, Jiang H, Zheng Q, Liao Q, Ding X, Xi Y.
J Cell Mol Med · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/jcmm.16400Apatinib induced ferroptosis by lipid peroxidation in gastric cancer.
Zhao L, Peng Y, He S, Li R, Wang Z, Huang J, Lei X, Li G, Ma Q.
Gastric Cancer · journal article · DOI 10.1007/s10120-021-01159-8Ferroptosis Inducers Are a Novel Therapeutic Approach for Advanced Prostate Cancer.
Ghoochani A, Hsu EC, Aslan M, Rice MA, Nguyen HM, Brooks JD, Corey E, Paulmurugan R, Stoyanova T.
Cancer Res · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-20-3477Tumor heterogeneity in autophagy-dependent ferroptosis.
Li J, Liu J, Xu Y, Wu R, Chen X, Song X, Zeh H, Kang R, Klionsky DJ, Wang X, Tang D.
Autophagy · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1080/15548627.2021.1872241Neuroprotective Effects of the Anti-cancer Drug Lapatinib Against Epileptic Seizures via Suppressing Glutathione Peroxidase 4-Dependent Ferroptosis.
Jia JN, Yin XX, Li Q, Guan QW, Yang N, Chen KN, Zhou HH, Mao XY.
Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2020.601572Hydrogen sulfide guards myoblasts from ferroptosis by inhibiting ALOX12 acetylation.
Wang Y, Yu R, Wu L, Yang G.
Cell Signal · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cellsig.2020.109870NCOA4-mediated ferritinophagy promotes ferroptosis induced by erastin, but not by RSL3 in HeLa cells.
Gryzik M, Asperti M, Denardo A, Arosio P, Poli M.
Biochim Biophys Acta Mol Cell Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbamcr.2020.118913Electron-Accepting Micelles Deplete Reduced Nicotinamide Adenine Dinucleotide Phosphate and Impair Two Antioxidant Cascades for Ferroptosis-Induced Tumor Eradication.
Guo X, Liu F, Deng J, Dai P, Qin Y, Li Z, Wang B, Fan A, Wang Z, Zhao Y.
ACS Nano · research support, non-u.s. gov't; journal article · DOI 10.1021/acsnano.0c00764A new role of glutathione peroxidase 4 during human erythroblast enucleation.
Ouled-Haddou H, Messaoudi K, Demont Y, Lopes Dos Santos R, Carola C, Caulier A, Vong P, Jankovsky N, Lebon D, Willaume A, Demagny J, Boyer T, Marolleau JP, Rochette J, Garçon L.
Blood Adv · research support, non-u.s. gov't; research-article; journal article · DOI 10.1182/bloodadvances.2020003100Tumor suppressor miR-424-5p abrogates ferroptosis in ovarian cancer through targeting ACSL4.
Ma LL, Liang L, Zhou D, Wang SW.
Neoplasma · journal article · DOI 10.4149/neo_2020_200707n705TGFβ2-mediated epithelial-mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance.
Jiang XM, Xu YL, Yuan LW, Zhang LL, Huang MY, Ye ZH, Su MX, Chen XP, Zhu H, Ye RD, Lu JJ.
Acta Pharmacol Sin · research-article; journal article · DOI 10.1038/s41401-020-0457-8Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death.
Liu Y, Wang Y, Liu J, Kang R, Tang D.
Cancer Gene Ther · research support, non-u.s. gov't; journal article · DOI 10.1038/s41417-020-0182-yAbrogation of ARF6 promotes RSL3-induced ferroptosis and mitigates gemcitabine resistance in pancreatic cancer cells.
Ye Z, Hu Q, Zhuo Q, Zhu Y, Fan G, Liu M, Sun Q, Zhang Z, Liu W, Xu W, Ji S, Yu X, Xu X, Qin Y.
Am J Cancer Res · research-article; journal articleFerroptosis, a novel pharmacological mechanism of anti-cancer drugs.
Su Y, Zhao B, Zhou L, Zhang Z, Shen Y, Lv H, AlQudsy LHH, Shang P.
Cancer Lett · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.canlet.2020.02.015Ginsenoside Re Mitigates 6-Hydroxydopamine-Induced Oxidative Stress through Upregulation of GPX4.
Lee GH, Lee WJ, Hur J, Kim E, Lee HG, Seo HG.
Molecules · research-article; journal article · DOI 10.3390/molecules25010188ESCRT-III-dependent membrane repair blocks ferroptosis.
Dai E, Meng L, Kang R, Wang X, Tang D.
Biochem Biophys Res Commun · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bbrc.2019.11.110Low-Concentration PTX And RSL3 Inhibits Tumor Cell Growth Synergistically By Inducing Ferroptosis In Mutant p53 Hypopharyngeal Squamous Carcinoma.
Ye J, Jiang X, Dong Z, Hu S, Xiao M.
Cancer Manag Res · research-article; journal article · DOI 10.2147/cmar.s217944Inactivation of the glutathione peroxidase GPx4 by the ferroptosis-inducing molecule RSL3 requires the adaptor protein 14-3-3ε.
Vučković AM, Bosello Travain V, Bordin L, Cozza G, Miotto G, Rossetto M, Toppo S, Venerando R, Zaccarin M, Maiorino M, Ursini F, Roveri A.
FEBS Lett · research support, non-u.s. gov't; journal article · DOI 10.1002/1873-3468.13631RSL3 induced autophagic death in glioma cells via causing glycolysis dysfunction.
Wang X, Lu S, He C, Wang C, Wang L, Piao M, Chi G, Luo Y, Ge P.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2019.08.096RSL3 Drives Ferroptosis Through GPX4 Inactivation and ROS Production in Colorectal Cancer.
Sui X, Zhang R, Liu S, Duan T, Zhai L, Zhang M, Han X, Xiang Y, Huang X, Lin H, Xie T.
Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2018.01371Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer.
Shin D, Kim EH, Lee J, Roh JL.
Free Radic Biol Med · research support, non-u.s. gov't; journal article · DOI 10.1016/j.freeradbiomed.2018.10.426Lipoxygenase-mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3.
Shintoku R, Takigawa Y, Yamada K, Kubota C, Yoshimoto Y, Takeuchi T, Koshiishi I, Torii S.
Cancer Sci · research-article; journal article · DOI 10.1111/cas.13380RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death.
Dächert J, Schoeneberger H, Rohde K, Fulda S.
Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.11687Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.
Yang WS, Stockwell BR.
Chem Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.chembiol.2008.02.010