Contre Sars-CoV-2, brequinar ou remdesivir ?
Manus JM.
Rev Francoph Lab · brief-report; journal article · DOI 10.1016/s1773-035x(21)00007-1 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
15 träffarBrequinar inhibits enterovirus replication by targeting biosynthesis pathway of pyrimidines.
Fu H, Zhang Z, Dai Y, Liu S, Fu E.
Am J Transl Res · research-article; journal articleThe Dihydroorotate Dehydrogenase Inhibitor Brequinar Is Synergistic with ENT1/2 Inhibitors.
Cuthbertson CR, Guo H, Kyani A, Madak JT, Arabzada Z, Neamati N.
ACS Pharmacol Transl Sci · research-article; journal article · DOI 10.1021/acsptsci.0c00124Identification and Tracking of Antiviral Drug Combinations.
Ianevski A, Yao R, Biza S, Zusinaite E, Mannik A, Kivi G, Planken A, Kurg K, Tombak EM, Ustav M, Shtaida N, Kulesskiy E, Jo E, Yang J, Lysvand H, Løseth K, Oksenych V, Aas PA, Tenson T, Vitkauskienė A, Windisch MP, Fenstad MH, Nordbø SA, Ustav M, Bjørås M, Kainov DE.
Viruses · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/v12101178A carboxylic acid isostere screen of the DHODH inhibitor Brequinar.
DeRatt LG, Christine Pietsch E, Tanner A, Shaffer P, Jacoby E, Wang W, Kazmi F, Zhang X, Attar RM, Edwards JP, Kuduk SD.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2020.127589Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine.
Andersen PI, Krpina K, Ianevski A, Shtaida N, Jo E, Yang J, Koit S, Tenson T, Hukkanen V, Anthonsen MW, Bjoras M, Evander M, Windisch MP, Zusinaite E, Kainov DE.
Viruses · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/v11100964Dihydroorotate dehydrogenase inhibitors in anti-infective drug research.
Boschi D, Pippione AC, Sainas S, Lolli ML.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2019.111681Antiviral activity of brequinar against foot-and-mouth disease virus infection in vitro and in vivo.
Li SF, Gong MJ, Sun YF, Shao JJ, Zhang YG, Chang HY.
Biomed Pharmacother · journal article · DOI 10.1016/j.biopha.2019.108982Re-evaluation of Brequinar sodium, a dihydroorotate dehydrogenase inhibitor.
Peters GJ.
Nucleosides Nucleotides Nucleic Acids · clinical trial, phase ii; multicenter study; journal article · DOI 10.1080/15257770.2018.1508692Design, Synthesis, and Characterization of Brequinar Conjugates as Probes to Study DHODH Inhibition.
Madak JT, Cuthbertson CR, Chen W, Showalter HD, Neamati N.
Chemistry · journal article · DOI 10.1002/chem.201702999Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.
He T, Haapa-Paananen S, Kaminskyy VO, Kohonen P, Fey V, Zhivotovsky B, Kallioniemi O, Perälä M.
Oncogene · research support, non-u.s. gov't; journal article · DOI 10.1038/onc.2013.313Potent antiviral activity of brequinar against the emerging Cantagalo virus in cell culture.
Schnellrath LC, Damaso CR.
Int J Antimicrob Agents · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ijantimicag.2011.07.002Characterization of dengue virus resistance to brequinar in cell culture.
Qing M, Zou G, Wang QY, Xu HY, Dong H, Yuan Z, Shi PY.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.00561-10The development of Brequinar as an immunosuppressive drug for transplantation.
Makowka L, Sher LS, Cramer DV.
Immunol Rev · review; journal article · DOI 10.1111/j.1600-065x.1993.tb00654.xActivity of a novel 4-quinolinecarboxylic acid, NSC 368390 [6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarb oxylic acid sodium salt], against experimental tumors.
Dexter DL, Hesson DP, Ardecky RJ, Rao GV, Tippett DL, Dusak BA, Paull KD, Plowman J, DeLarco BM, Narayanan VL.
Cancer Res · journal article