Acetylene Group, Friend or Foe in Medicinal Chemistry.
Talele TT.
J Med Chem · journal article · DOI 10.1021/acs.jmedchem.9b01617 PUBLIKATIONSREGISTRET
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14 träffarPropargylamine-derived multi-target directed ligands for Alzheimer's disease therapy.
do Carmo Carreiras M, Ismaili L, Marco-Contelles J.
Bioorg Med Chem Lett · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.bmcl.2019.126880Current and emerging therapeutic targets of alzheimer's disease for the design of multi-target directed ligands.
Blaikie L, Kay G, Kong Thoo Lin P.
Medchemcomm · review-article; review; journal article · DOI 10.1039/c9md00337aRasagiline derivatives combined with histamine H<sub>3</sub> receptor properties.
Lutsenko K, Hagenow S, Affini A, Reiner D, Stark H.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2019.08.016Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.
Zhou J, Jiang X, He S, Jiang H, Feng F, Liu W, Qu W, Sun H.
J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.9b00017Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease.
Wang T, Liu XH, Guan J, Ge S, Wu MB, Lin JP, Yang LR.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2019.02.076Anti-cholinesterase hybrids as multi-target-directed ligands against Alzheimer's disease (1998-2018).
Mishra P, Kumar A, Panda G.
Bioorg Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.bmc.2019.01.025Design, synthesis and evaluation of indole derivatives as multifunctional agents against Alzheimer's disease.
Denya I, Malan SF, Enogieru AB, Omoruyi SI, Ekpo OE, Kapp E, Zindo FT, Joubert J.
Medchemcomm · research-article; journal article · DOI 10.1039/c7md00569eInhibition of cholinesterase and monoamine oxidase-B activity by Tacrine-Homoisoflavonoid hybrids.
Sun Y, Chen J, Chen X, Huang L, Li X.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2013.09.050Design, synthesis, and evaluation of multitarget-directed resveratrol derivatives for the treatment of Alzheimer's disease.
Lu C, Guo Y, Yan J, Luo Z, Luo HB, Yan M, Huang L, Li X.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm400567sCarbamate derivatives of indolines as cholinesterase inhibitors and antioxidants for the treatment of Alzheimer's disease.
Yanovsky I, Finkin-Groner E, Zaikin A, Lerman L, Shalom H, Zeeli S, Weill T, Ginsburg I, Nudelman A, Weinstock M.
J Med Chem · journal article · DOI 10.1021/jm301411gMultitarget-directed benzylideneindanone derivatives: anti-β-amyloid (Aβ) aggregation, antioxidant, metal chelation, and monoamine oxidase B (MAO-B) inhibition properties against Alzheimer's disease.
Huang L, Lu C, Sun Y, Mao F, Luo Z, Su T, Jiang H, Shan W, Li X.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm300978hMulti-target-directed ligands to combat neurodegenerative diseases.
Cavalli A, Bolognesi ML, Minarini A, Rosini M, Tumiatti V, Recanatini M, Melchiorre C.
J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/jm7009364Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues.
Hubálek F, Binda C, Li M, Herzig Y, Sterling J, Youdim MB, Mattevi A, Edmondson DE.
J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm0310885