ActiQs / Forskning

PUBLIKATIONSREGISTRET

Gå till forskningen.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för Butylphthalide. Visa hela publikationsregistret

En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publikationer i urvalet

21 träffar

Bibliografisk träff 2024-06-01

Discovery of orally bioavailable phenyltetrazolium derivatives for the acute treatment and the secondary prevention of ischemic stroke.

Lu Y, Lin H, Xu Y, Shen Z, Guo Y, Jin Y, Shi Q, Chen H, Zhuang Y, Huang W, Che J, Dai H, Dong X.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2024.116542

Bibliografisk träff 2024-05-01

Research progress of prodrugs for the treatment of cerebral ischemia.

Zheng H, Wu H, Wang D, Wang S, Ji D, Liu X, Gao G, Su X, Zhang Y, Ling Y.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2024.116457

Bibliografisk träff 2023-12-26

Synthesis and evaluation of butylphthalide-scutellarein hybrids as multifunctional agents for the treatment of Alzheimer's disease.

Yu G, Shi Y, Cong S, Wu C, Liu J, Zhang Y, Liu H, Liu X, Deng H, Tan Z, Deng Y.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.116099

Bibliografisk träff 2023-03-07

Discovery of phenylcarbamoyl xanthone derivatives as potent neuroprotective agents for treating ischemic stroke.

Chen YL, Chen YC, Xiong LA, Huang QY, Gong TT, Chen Y, Ma LF, Fang L, Zhan ZJ.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.115251

Bibliografisk träff 2022-07-21

Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment.

Wang H, Cui E, Li J, Ma X, Jiang X, Du S, Qian S, Du L.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2022.114597

Bibliografisk träff 2022-04-18

Discovery of small-molecule compounds and natural products against Parkinson's disease: Pathological mechanism and structural modification.

Zhong Z, He X, Ge J, Zhu J, Yao C, Cai H, Ye XY, Xie T, Bai R.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2022.114378

Bibliografisk träff 2022-02-11

Discovery of novel 3-butyl-6-benzyloxyphthalide Mannich base derivatives as multifunctional agents against Alzheimer's disease.

Liu Z, Shi Y, Zhang X, Yu G, Li J, Cong S, Deng Y.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2022.116660

Bibliografisk träff 2021-10-08

Discovery of novel brain-penetrant GluN2B NMDAR antagonists via pharmacophore-merging strategy as anti-stroke therapeutic agents.

Xu Q, Hu M, Li J, Ma X, Chu Z, Zhu Q, Zhang Y, Zhu P, Huang Y, He G.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113876

Bibliografisk träff 2021-03-17

Design, synthesis and biological evaluation of brain penetrant benzazepine-based histone deacetylase 6 inhibitors for alleviating stroke-induced brain infarction.

Guo Z, Zhang Z, Zhang Y, Wang G, Huang Z, Zhang Q, Li J.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113383

Bibliografisk träff 2021-02-16

Novel 3-benzylidene/benzylphthalide Mannich base derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.

Cao Z, Song Q, Yu G, Liu Z, Cong S, Tan Z, Deng Y.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2021.116074

Bibliografisk träff 2020-02-26

Design, synthesis and evaluation of phthalide alkyl tertiary amine derivatives as promising acetylcholinesterase inhibitors with high potency and selectivity against Alzheimer's disease.

Luo L, Song Q, Li Y, Cao Z, Qiang X, Tan Z, Deng Y.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2020.115400

Bibliografisk träff 2017-12-01

Pyrano[3,2-a]carbazole alkaloids as effective agents against ischemic stroke in vitro and in vivo.

Zang Y, Song X, Li C, Ma J, Chu S, Liu D, Ren Q, Li Y, Chen N, Zhang D.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.11.084

Bibliografisk träff 2017-01-17

DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-β aggregation and monoamine oxidases with high antioxidant potency for Alzheimer's therapy.

Qiang X, Li Y, Yang X, Luo L, Xu R, Zheng Y, Cao Z, Tan Z, Deng Y.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2017.01.050

Bibliografisk träff 2016-03-19

Discovery of a ring-opened derivative of 3-n-butylphthalide bearing NO/H2S-donating moieties as a potential anti-ischemic stroke agent.

Yin W, Lan L, Huang Z, Ji J, Fang J, Wang X, Ji H, Peng S, Xu J, Zhang Y.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2016.03.044

Bibliografisk träff 2016-02-23

Recent progress towards an effective treatment of amyotrophic lateral sclerosis using the SOD1 mouse model in a preclinical setting.

Browne EC, Abbott BM.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2016.02.048

Bibliografisk träff 2015-07-03

Novel hybrids of 3-n-butylphthalide and edaravone: Design, synthesis and evaluations as potential anti-ischemic stroke agents.

Sheng X, Hua K, Yang C, Wang X, Ji H, Xu J, Huang Z, Zhang Y.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2015.06.090

Bibliografisk träff 2013-02-15

Synthesis and biological evaluation of nitric oxide releasing derivatives of 6-amino-3-n-butylphthalide as potential antiplatelet agents.

Wang X, Wang L, Huang Z, Sheng X, Li T, Ji H, Xu J, Zhang Y.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2013.02.035

Bibliografisk träff 2012-08-07

Discovery of a potential anti-ischemic stroke agent: 3-pentylbenzo[c]thiophen-1(3H)-one.

Wu J, Ling J, Wang X, Li T, Liu J, Lai Y, Ji H, Peng S, Tian J, Zhang Y.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm300681r

Bibliografisk träff 2011-05-27

Synthesis and evaluation of nitric oxide-releasing derivatives of 3-n-butylphthalide as anti-platelet agents.

Li Y, Wang X, Fu R, Yu W, Wang X, Lai Y, Peng S, Zhang Y.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2011.05.082

Bibliografisk träff 2010-01-25

Synthesis and biological activity of n-butylphthalide derivatives.

Wang W, Cha XX, Reiner J, Gao Y, Qiao HL, Shen JX, Chang JB.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2010.01.036

Bibliografisk träff 2007-07-01

Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone.

Yang H, Hu GY, Chen J, Wang Y, Wang ZH.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2007.06.082