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Publikationer i urvalet

22 träffar

Bibliografisk träff 2015-05-22

Isolation and Pharmacological Evaluation of Minor Cannabinoids from High-Potency Cannabis sativa.

Radwan MM, ElSohly MA, El-Alfy AT, Ahmed SA, Slade D, Husni AS, Manly SP, Wilson L, Seale S, Cutler SJ, Ross SA.

J Nat Prod · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jnatprod.5b00065

Bibliografisk träff 2013-12-10

Controlled-deactivation cannabinergic ligands.

Sharma R, Nikas SP, Paronis CA, Wood JT, Halikhedkar A, Guo JJ, Thakur GA, Kulkarni S, Benchama O, Raghav JG, Gifford RS, Järbe TU, Bergman J, Makriyannis A.

J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm4016075

Bibliografisk träff 2013-08-08

Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists.

Han S, Thatte J, Buzard DJ, Jones RM.

J Med Chem · review; journal article · DOI 10.1021/jm4005626

Bibliografisk träff 2009-02-04

Design and synthesis of novel tri-aryl CB2 selective cannabinoid ligands.

Bhattacharjee H, Gurley SN, Moore BM.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.01.100

Bibliografisk träff 2008-12-03

Quantitative structure-activity relationship (QSAR) for a series of novel cannabinoid derivatives using descriptors derived from semi-empirical quantum-chemical calculations.

Ferreira AM, Krishnamurthy M, Moore BM, Finkelstein D, Bashford D.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2008.11.059

Bibliografisk träff 2008-10-01

Bornyl- and isobornyl-Delta8-tetrahydrocannabinols: a novel class of cannabinergic ligands.

Lu D, Guo J, Duclos RI, Bowman AL, Makriyannis A.

J Med Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/jm8005299

Bibliografisk träff 2008-05-20

Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs.

Krishnamurthy M, Gurley S, Moore BM.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2008.05.034

Bibliografisk träff 2007-10-17

Combined 3D QSAR and molecular docking studies to reveal novel cannabinoid ligands with optimum binding activity.

Durdagi S, Papadopoulos MG, Papahatjis DP, Mavromoustakos T.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2007.10.044

Bibliografisk träff 2007-05-24

The application of 3D-QSAR studies for novel cannabinoid ligands substituted at the C1' position of the alkyl side chain on the structural requirements for binding to cannabinoid receptors CB1 and CB2.

Durdagi S, Kapou A, Kourouli T, Andreou T, Nikas SP, Nahmias VR, Papahatjis DP, Papadopoulos MG, Mavromoustakos T.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0610705

Bibliografisk träff 2006-01-04

Structural modifications of the cannabinoid side chain towards C3-aryl and 1',1'-cycloalkyl-1'-cyano cannabinoids.

Papahatjis DP, Nahmias VR, Andreou T, Fan P, Makriyannis A.

Bioorg Med Chem Lett · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2005.12.026

Bibliografisk träff 2006-01-01

3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data.

Salo OM, Savinainen JR, Parkkari T, Nevalainen T, Lahtela-Kakkonen M, Gynther J, Laitinen JT, Järvinen T, Poso A.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm0505157

Bibliografisk träff 2005-07-01

Adamantyl cannabinoids: a novel class of cannabinergic ligands.

Lu D, Meng Z, Thakur GA, Fan P, Steed J, Tartal CL, Hurst DP, Reggio PH, Deschamps JR, Parrish DA, George C, Järbe TU, Lamb RJ, Makriyannis A.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/jm058175c

Bibliografisk träff 2002-12-01

Novel 1',1'-chain substituted Delta(8)-tetrahydrocannabinols.

Papahatjis DP, Nikas SP, Andreou T, Makriyannis A.

Bioorg Med Chem Lett · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1016/s0960-894x(02)00785-0

Bibliografisk träff 1999-08-01

Novel conformationally restricted tetracyclic analogs of delta8-tetrahydrocannabinol.

Khanolkar AD, Lu D, Fan P, Tian X, Makriyannis A.

Bioorg Med Chem Lett · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/s0960-894x(99)00355-8

Bibliografisk träff 1992-08-01

5'-Azido-delta 8-THC: a novel photoaffinity label for the cannabinoid receptor.

Charalambous A, Yan G, Houston DB, Howlett AC, Compton DR, Martin BR, Makriyannis A.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00094a023

Bibliografisk träff 1991-11-01

Synthesis and pharmacological evaluation of ether and related analogues of delta 8-, delta 9-, and delta 9,11-tetrahydrocannabinol.

Compton DR, Prescott WR, Martin BR, Siegel C, Gordon PM, Razdan RK.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00115a023

Bibliografisk träff 1990-03-01

Cannabimimetic activity of novel enantiomeric, benzofuran cannabinoids.

Mechoulam R, Breuer A, Järbe TU, Hiltunen AJ, Glaser R.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm00165a024

Bibliografisk träff 1989-07-01

The importance of the orientation of the C9 substituent to cannabinoid activity.

Reggio PH, Greer KV, Cox SM.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00127a038

Bibliografisk träff 1984-10-01

Activity of novel aminocannabinoids in baboons.

Edery H, Porath G, Mechoulam R, Lander N, Srebnik M, Lewis N.

J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00376a029

Bibliografisk träff 1979-07-01

Some 11-substituted tetrahydrocannabinols. Synthesis and comparison with the potent cannabinoid metabolites 11-hydroxytetrahydrocannabinols.

Wilson RS, Martin BR, Dewey WL.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00193a025

Bibliografisk träff 1978-12-01

Molar volume relationships and the specific inhibition of a synaptosomal enzyme by psychoactive cannabinoids.

Greenberg JH, Mellors A, McGowan JC.

J Med Chem · journal article · DOI 10.1021/jm00210a007

Bibliografisk träff 1978-10-01

Synthesis and pharmacological activity of a phosphate ester of delta8-tetrahydrocannabinol.

Yoshimura H, Watanabe K, Oguri K, Fujiwara M, Ueki S.

J Med Chem · journal article · DOI 10.1021/jm00208a014