Dimerization decrypts antibiotic activity.
Smith M.
Science · comment; research support, non-u.s. gov't; journal article · DOI 10.1126/science.abn8327 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
13 träffarTotal synthesis of himastatin.
D'Angelo KA, Schissel CK, Pentelute BL, Movassaghi M.
Science · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1126/science.abm6509Enhancement of himastatin bioproduction via inactivation of atypical repressors in <i>Streptomyces hygroscopicus</i>.
Xie Y, Li Q, Qin X, Ju J, Ma J.
Metab Eng Commun · research-article; journal article · DOI 10.1016/j.mec.2018.e00084Molecular characterization of the hydroxylase HmtN at 1.3 Å resolution.
Zhang H, Chen J, Zhang H.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2017.07.010Structural analysis of HmtT and HmtN involved in the tailoring steps of himastatin biosynthesis.
Zhang H, Chen J, Wang H, Xie Y, Ju J, Yan Y, Zhang H.
FEBS Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.febslet.2013.04.013Biosynthesis of himastatin: assembly line and characterization of three cytochrome P450 enzymes involved in the post-tailoring oxidative steps.
Ma J, Wang Z, Huang H, Luo M, Zuo D, Wang B, Sun A, Cheng YQ, Zhang C, Ju J.
Angew Chem Int Ed Engl · research support, non-u.s. gov't; journal article · DOI 10.1002/anie.201102305Discovery through total synthesis: a retrospective on the himastatin problem.
Kamenecka TM, Danishefsky SJ.
Chemistry · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1002/1521-3765(20010105)7:1<41::aid-chem41>3.0.co;2-dStudies in the Total Synthesis of Himastatin: A Revision of the Stereochemical Assignment.
Kamenecka TM, Danishefsky SJ.
Angew Chem Int Ed Engl · journal article · DOI 10.1002/(sici)1521-3773(19981116)37:21<2993::aid-anie2993>3.0.co;2-iTotal Synthesis of Himastatin: Confirmation of the Revised Stereostructure.
Kamenecka TM, Danishefsky SJ.
Angew Chem Int Ed Engl · journal article · DOI 10.1002/(sici)1521-3773(19981116)37:21<2995::aid-anie2995>3.0.co;2-6Himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus. III. Structural elucidation.
Leet JE, Schroeder DR, Golik J, Matson JA, Doyle TW, Lam KS, Hill SE, Lee MS, Whitney JL, Krishnan BS.
J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.49.299Inhibition of antibacterial activity of himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus, by fatty acid sodium salts.
Mamber SW, Brookshire KW, Dean BJ, Firestone RA, Leet JE, Matson JA, Forenza S.
Antimicrob Agents Chemother · research-article; journal article · DOI 10.1128/aac.38.11.2633Himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus. I. Taxonomy of producing organism, fermentation and biological activity.
Lam KS, Hesler GA, Mattei JM, Mamber SW, Forenza S, Tomita K.
J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.43.956Himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus. II. Isolation and characterization.
Leet JE, Schroeder DR, Krishnan BS, Matson JA.
J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.43.961