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Publikationer i urvalet

11 träffar

Bibliografisk träff 2019-06-05

Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition.

Long T, Hassan A, Thompson BM, McDonald JG, Wang J, Li X.

Nat Commun · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41467-019-10279-w

Bibliografisk träff 2009-01-21

Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition.

Duniec-Dmuchowski Z, Fang HL, Strom SC, Ellis E, Runge-Morris M, Kocarek TA.

Drug Metab Dispos · research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/dmd.108.025130

Bibliografisk träff 2005-07-01

Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening.

Laggner C, Schieferer C, Fiechtner B, Poles G, Hoffmann RD, Glossmann H, Langer T, Moebius FF.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm049073+

Bibliografisk träff 2005-06-01

Comparison of effects of U18666A and enantiomeric U18666A on sterol synthesis and induction of apoptosis.

Cenedella RJ, Sexton PS, Krishnan K, Covey DF.

Lipids · comparative study; research support, u.s. gov't, p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1007/s11745-005-1426-9

Bibliografisk träff 2004-07-31

Early-phase redistribution of the cation-independent mannose 6-phosphate receptor by U18666A treatment in HeLa cells.

Tomiyama Y, Waguri S, Kanamori S, Kametaka S, Wakasugi M, Shibata M, Ebisu S, Uchiyama Y.

Cell Tissue Res · research support, non-u.s. gov't; journal article · DOI 10.1007/s00441-004-0941-3

Bibliografisk träff 2004-05-01

Induction of CYP3A by 2,3-oxidosqualene:lanosterol cyclase inhibitors is mediated by an endogenous squalene metabolite in primary cultured rat hepatocytes.

Shenoy SD, Spencer TA, Mercer-Haines NA, Abdolalipour M, Wurster WL, Runge-Morris M, Kocarek TA.

Mol Pharmacol · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1124/mol.65.5.1302

Bibliografisk träff 2001-02-01

Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions.

Bae S, Seong J, Paik Y.

Biochem J · research support, non-u.s. gov't; research-article; journal article · DOI 10.1042/0264-6021:3530689

Bibliografisk träff 1998-03-01

Effects of intracellular free cholesterol accumulation on macrophage viability: a model for foam cell death.

Kellner-Weibel G, Jerome WG, Small DM, Warner GJ, Stoltenborg JK, Kearney MA, Corjay MH, Phillips MC, Rothblat GH.

Arterioscler Thromb Vasc Biol · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1161/01.atv.18.3.423

Bibliografisk träff 1983-12-01

Effects of 3 beta-[2-(diethylamino)ethoxy]androst-5-en-17-one on the synthesis of cholesterol and ubiquinone in rat intestinal epithelial cell cultures.

Sexton RC, Panini SR, Azran F, Rudney H.

Biochemistry · research support, u.s. gov't, p.h.s.; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/bi00294a001

Bibliografisk träff 1979-06-01

Mechanism of cataract production by 3-beta(2-diethylaminoethoxy) androst-5-en-17-one hydrochloride, U18666A: an inhibitor of cholesterol biosynthesis.

Cenedella RJ, Bierkamper GG.

Exp Eye Res · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/0014-4835(79)90068-x

Bibliografisk träff 1976-01-01

Nonisotopic method for estimating cholesterogenesis in the rat.

Phillips WA, Ratchford JM, Schulta JR.

Adv Exp Med Biol · journal article · DOI 10.1007/978-1-4614-4618-7_15