Gå till forskningen.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för 5-pyrimidinecarboxamide, 2-[(2,4-dichlorophenyl)amino]-n-[(tetrahydro-2h-pyran-4-yl)methyl]-4-(trifluoromethyl)-. Visa hela publikationsregistret

En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publikationer i urvalet

11 träffar

Bibliografisk träff 2017-05-30

Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies.

Qian HY, Wang ZL, Xie XY, Pan YL, Li GJ, Xie X, Chen JZ.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.05.060

Bibliografisk träff 2017-05-01

Development of Quinazoline/Pyrimidine-2,4(1<i>H</i>,3<i>H</i>)-diones as Agonists of Cannabinoid Receptor Type 2.

Qian HY, Wang ZL, Pan YL, Chen LL, Xie X, Chen JZ.

ACS Med Chem Lett · brief-report; journal article · DOI 10.1021/acsmedchemlett.7b00007

Bibliografisk träff 2015-07-23

Development of Quinoline-2,4(1H,3H)-diones as Potent and Selective Ligands of the Cannabinoid Type 2 Receptor.

Han S, Zhang FF, Qian HY, Chen LL, Pu JB, Xie X, Chen JZ.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.5b00227

Bibliografisk träff 2015-01-26

Design, syntheses, structure-activity relationships and docking studies of coumarin derivatives as novel selective ligands for the CB2 receptor.

Han S, Zhang FF, Qian HY, Chen LL, Pu JB, Xie X, Chen JZ.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.01.054

Bibliografisk träff 2009-10-01

Discovery of 1-[4-(3-chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone (GSK554418A), a brain penetrant 5-azaindole CB2 agonist for the treatment of chronic pain.

Giblin GM, Billinton A, Briggs M, Brown AJ, Chessell IP, Clayton NM, Eatherton AJ, Goldsmith P, Haslam C, Johnson MR, Mitchell WL, Naylor A, Perboni A, Slingsby BP, Wilson AW.

J Med Chem · journal article · DOI 10.1021/jm9009857

Bibliografisk träff 2009-02-12

Morpholine containing CB2 selective agonists.

Zindell R, Riether D, Bosanac T, Berry A, Gemkow MJ, Ebneth A, Löbbe S, Raymond EL, Thome D, Shih DT, Thomson D.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2009.02.033

Bibliografisk träff 2009-01-01

Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow.

Markt P, Feldmann C, Rollinger JM, Raduner S, Schuster D, Kirchmair J, Distinto S, Spitzer GM, Wolber G, Laggner C, Altmann KH, Langer T, Gertsch J.

J Med Chem · validation study; journal article · DOI 10.1021/jm801044g

Bibliografisk träff 2008-11-05

Pyridine-3-carboxamides as novel CB(2) agonists for analgesia.

Mitchell WL, Giblin GM, Naylor A, Eatherton AJ, Slingsby BP, Rawlings AD, Jandu KS, Haslam CP, Brown AJ, Goldsmith P, Clayton NM, Wilson AW, Chessell IP, Green RH, Whittington AR, Wall ID.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.10.118

Bibliografisk träff 2008-01-18

Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity.

Ermann M, Riether D, Walker ER, Mushi IF, Jenkins JE, Noya-Marino B, Brewer ML, Taylor MG, Amouzegh P, East SP, Dymock BW, Gemkow MJ, Kahrs AF, Ebneth A, Löbbe S, O'Shea K, Shih DT, Thomson D.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.01.042

Bibliografisk träff 2007-11-01

Imine derivatives as new potent and selective CB2 cannabinoid receptor agonists with an analgesic action.

Ohta H, Ishizaka T, Tatsuzuki M, Yoshinaga M, Iida I, Yamaguchi T, Tomishima Y, Futaki N, Toda Y, Saito S.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2007.10.087

Bibliografisk träff 2007-05-04

Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.

Giblin GM, O'Shaughnessy CT, Naylor A, Mitchell WL, Eatherton AJ, Slingsby BP, Rawlings DA, Goldsmith P, Brown AJ, Haslam CP, Clayton NM, Wilson AW, Chessell IP, Wittington AR, Green R.

J Med Chem · journal article · DOI 10.1021/jm061195+