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Publikationer i urvalet

27 träffar

Bibliografisk träff 2021-02-16

Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells.

Parkhitko AA, Singh A, Hsieh S, Hu Y, Binari R, Lord CJ, Hannenhalli S, Ryan CJ, Perrimon N.

PLoS Genet · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pgen.1009354

Bibliografisk träff 2020-12-04

UBE1a Suppresses Herpes Simplex Virus-1 Replication.

Ikeda M, Ito A, Sekine Y, Fujimuro M.

Viruses · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/v12121391

Bibliografisk träff 2020-10-31

Inhibition of deubiquitination by PR-619 induces apoptosis and autophagy via ubi-protein aggregation-activated ER stress in oesophageal squamous cell carcinoma.

Wang L, Li M, Sha B, Hu X, Sun Y, Zhu M, Xu Y, Li P, Wang Y, Guo Y, Li J, Shi J, Li P, Hu T, Chen P.

Cell Prolif · research-article; journal article · DOI 10.1111/cpr.12919

Bibliografisk träff 2020-09-10

A novel positive feedback-loop between the HTLV-1 oncoprotein Tax and NF-κB activity in T-cells.

Millen S, Meretuk L, Göttlicher T, Schmitt S, Fleckenstein B, Thoma-Kress AK.

Retrovirology · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s12977-020-00538-w

Bibliografisk träff 2020-07-16

Ubiquitin specific protease 5 negatively regulates the IFNs-mediated antiviral activity via targeting SMURF1.

Qian G, Zhu L, Huang C, Liu Y, Ren Y, Ding Y, Qian W, Xu Q, Zheng H, Lv H.

Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2020.106763

Bibliografisk träff 2020-04-16

Doxorubicin induces large-scale and differential H2A and H2B redistribution in live cells.

Nánási P, Imre L, Firouzi Niaki E, Bosire R, Mocsár G, Türk-Mázló A, Ausio J, Szabó G.

PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0231223

Bibliografisk träff 2020-03-23

Docosahexaenoic acid inhibits zymogen activation by suppressing vacuolar ATPase activation in cerulein-stimulated pancreatic acinar cells.

Park Y, Ku L, Lim JW, Kim H.

Genes Nutr · research-article; journal article · DOI 10.1186/s12263-020-00664-2

Bibliografisk träff 2020-03-20

Inhibition of the Ubiquitin-Activating Enzyme UBA1 Suppresses Diet-Induced Atherosclerosis in Apolipoprotein E-Knockout Mice.

Liao J, Yang X, Lin Q, Liu S, Xie Y, Xia Y, Li HH.

J Immunol Res · research-article; journal article · DOI 10.1155/2020/7812709

Bibliografisk träff 2020-02-28

Semaphorin-3A Promotes Degradation of Fragile X Mental Retardation Protein in Growth Cones <i>via</i> the Ubiquitin-Proteasome Pathway.

Takabatake M, Goshima Y, Sasaki Y.

Front Neural Circuits · research support, non-u.s. gov't; research-article; journal article · DOI 10.3389/fncir.2020.00005

Bibliografisk träff 2019-01-01

Galectin-9 induces atypical ubiquitination leading to cell death in PC-3 prostate cancer cells.

Itoh A, Nonaka Y, Ogawa T, Nakamura T, Nishi N.

Glycobiology · research support, non-u.s. gov't; journal article · DOI 10.1093/glycob/cwy099

Bibliografisk träff 2018-09-26

Dynamic regulation of dynein localization revealed by small molecule inhibitors of ubiquitination enzymes.

Monda JK, Cheeseman IM.

Open Biol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1098/rsob.180095

Bibliografisk träff 2018-09-22

Administration of ubiquitin-activating enzyme UBA1 inhibitor PYR-41 attenuates angiotensin II-induced cardiac remodeling in mice.

Shu Q, Lai S, Wang XM, Zhang YL, Yang XL, Bi HL, Li HH.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2018.09.100

Bibliografisk träff 2018-07-05

PYR-41 and Thalidomide Impair Dendritic Cell Cross-Presentation by Inhibiting Myddosome Formation and Attenuating the Endosomal Recruitments of p97 and Sec61 via NF-<i>κ</i>B Inactivation.

You X, Xu DD, Zhang D, Chen J, Gao FG.

J Immunol Res · research-article; journal article · DOI 10.1155/2018/5070573

Bibliografisk träff 2018-05-17

Inhibition of ubiquitin-activating enzyme protects against organ injury after intestinal ischemia-reperfusion.

Matsuo S, Chaung A, Liou D, Wang P, Yang WL.

Am J Physiol Gastrointest Liver Physiol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1152/ajpgi.00024.2018

Bibliografisk träff 2018-04-01

PYR-41, A Ubiquitin-Activating Enzyme E1 Inhibitor, Attenuates Lung Injury in Sepsis.

Matsuo S, Sharma A, Wang P, Yang WL.

Shock · research-article; journal article; research support, n.i.h., extramural · DOI 10.1097/shk.0000000000000931

Bibliografisk träff 2018-02-03

Ubiquitin-activating enzyme E1 inhibitor PYR-41 retards sperm enlargement after fusion to the egg.

Yoshida K, Kang W, Nakamura A, Kawano N, Hanai M, Miyado M, Miyamoto Y, Iwai M, Hamatani T, Saito H, Miyado K, Umezawa A.

Reprod Toxicol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.reprotox.2018.01.001

Bibliografisk träff 2017-11-28

Nicotine increases apoptosis in HUVECs cultured in high glucose/high fat via Akt ubiquitination and degradation.

Cao X, Han C, Wen J, Guo X, Zhang K.

Clin Exp Pharmacol Physiol · journal article · DOI 10.1111/1440-1681.12865

Bibliografisk träff 2017-05-25

PKC-α Triggers EGFR Ubiquitination, Endocytosis and ERK Activation in Podocytes Stimulated with High Glucose.

Lei CT, Wei YH, Tang H, Wen Q, Ye C, Zhang C, Su H.

Cell Physiol Biochem · journal article · DOI 10.1159/000477329

Bibliografisk träff 2016-02-13

The ubiquitin-activating enzyme E1 as a novel therapeutic target for the treatment of restenosis.

Qin Z, Cui B, Jin J, Song M, Zhou B, Guo H, Qian D, He Y, Huang L.

Atherosclerosis · research support, non-u.s. gov't; journal article · DOI 10.1016/j.atherosclerosis.2016.02.016

Bibliografisk träff 2015-07-01

TRPM8 channel as a novel molecular target in androgen-regulated prostate cancer cells.

Asuthkar S, Velpula KK, Elustondo PA, Demirkhanyan L, Zakharian E.

Oncotarget · research-article; journal article; research support, n.i.h., extramural · DOI 10.18632/oncotarget.3948

Bibliografisk träff 2014-12-16

Palmitate induces insulin resistance in human HepG2 hepatocytes by enhancing ubiquitination and proteasomal degradation of key insulin signaling molecules.

Ishii M, Maeda A, Tani S, Akagawa M.

Arch Biochem Biophys · research support, non-u.s. gov't; journal article · DOI 10.1016/j.abb.2014.12.009

Bibliografisk träff 2014-08-19

Ubiquitin-activating enzyme is necessary for 17β-estradiol-induced breast cancer cell proliferation and migration.

Pesiri V, Totta P, Marino M, Acconcia F.

IUBMB Life · research support, non-u.s. gov't; journal article · DOI 10.1002/iub.1296

Bibliografisk träff 2014-06-01

Ubiquitin-activating enzyme E1 inhibitor PYR41 attenuates angiotensin II-induced activation of dendritic cells via the IκBa/NF-κB and MKP1/ERK/STAT1 pathways.

Chen C, Meng Y, Wang L, Wang HX, Tian C, Pang GD, Li HH, Du J.

Immunology · research support, non-u.s. gov't; journal article · DOI 10.1111/imm.12255

Bibliografisk träff 2013-01-16

Iduna protects HT22 cells from hydrogen peroxide-induced oxidative stress through interfering poly(ADP-ribose) polymerase-1-induced cell death (parthanatos).

Xu H, Luo P, Zhao Y, Zhao M, Yang Y, Chen T, Huo K, Han H, Fei Z.

Cell Signal · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cellsig.2013.01.006

Bibliografisk träff 2011-09-27

Ubiquitin-activating enzyme (UBA1) is required for sperm capacitation, acrosomal exocytosis and sperm-egg coat penetration during porcine fertilization.

Yi YJ, Zimmerman SW, Manandhar G, Odhiambo JF, Kennedy C, Jonáková V, Maňásková-Postlerová P, Sutovsky M, Park CS, Sutovsky P.

Int J Androl · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1111/j.1365-2605.2011.01217.x

Bibliografisk träff 2011-05-19

Protein cross-linking as a novel mechanism of action of a ubiquitin-activating enzyme inhibitor with anti-tumor activity.

Kapuria V, Peterson LF, Showalter HD, Kirchhoff PD, Talpaz M, Donato NJ.

Biochem Pharmacol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2011.05.012

Bibliografisk träff 2007-10-01

Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics.

Yang Y, Kitagaki J, Dai RM, Tsai YC, Lorick KL, Ludwig RL, Pierre SA, Jensen JP, Davydov IV, Oberoi P, Li CC, Kenten JH, Beutler JA, Vousden KH, Weissman AM.

Cancer Res · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-07-0568