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Publikationer i urvalet

22 träffar

Bibliografisk träff 2022-10-26

Treatment of multiple synchronous canine mast cell tumours using intratumoural tigilanol tiglate.

Brown GK, Finlay JR, Straw RC, Ziea JY, Leung B, O'Connell K, Thomson MJ, Campbell JE, Jones PD, Reddell P.

Front Vet Sci · research-article; journal article · DOI 10.3389/fvets.2022.1003165

Bibliografisk träff 2022-10-03

Practical synthesis of the therapeutic leads tigilanol tiglate and its analogues.

Wender PA, Gentry ZO, Fanelli DJ, Luu-Nguyen QH, McAteer OD, Njoo E.

Nat Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41557-022-01048-2

Bibliografisk träff 2022-08-16

Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (<i>Fontainea picrosperma</i>).

Chianese G, Amin HIM, Maioli C, Reddell P, Parsons P, Cullen J, Johns J, Handoko H, Boyle G, Appendino G, Taglialatela-Scafati O, Gaeta S.

J Nat Prod · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1021/acs.jnatprod.2c00226

Bibliografisk träff 2022-06-21

Identification of Gene Biomarkers for Tigilanol Tiglate Content in <i>Fontainea picrosperma</i>.

Mitu SA, Stewart P, Tran TD, Reddell PW, Cummins SF, Ogbourne SM.

Molecules · research-article; journal article · DOI 10.3390/molecules27133980

Bibliografisk träff 2022-06-01

[New drugs for small animals in 2021].

Emmerich IU.

Tierarztl Prax Ausg K Kleintiere Heimtiere · journal article · DOI 10.1055/a-1867-2855

Bibliografisk träff 2022-06-01

[Successful local treatment of a digital canine mast cell tumour with Tigilanol Tiglate].

Gasser K.

Tierarztl Prax Ausg K Kleintiere Heimtiere · journal article · DOI 10.1055/a-1844-8554

Bibliografisk träff 2021-12-15

Tigilanol Tiglate-Mediated Margins: A Comparison With Surgical Margins in Successful Treatment of Canine Mast Cell Tumours.

De Ridder T, Reddell P, Jones P, Brown G, Campbell J.

Front Vet Sci · research-article; journal article · DOI 10.3389/fvets.2021.764800

Bibliografisk träff 2021-09-01

Advice on using Stelfonta 1 mg/ml solution for dogs.

Diesel G, Anderson N.

Vet Rec · journal article · DOI 10.1002/vetr.1000

Bibliografisk träff 2021-08-27

Intratumoural Treatment of 18 Cytologically Diagnosed Canine High-Grade Mast Cell Tumours With Tigilanol Tiglate.

Brown GK, Campbell JE, Jones PD, De Ridder TR, Reddell P, Johannes CM.

Front Vet Sci · research-article; journal article · DOI 10.3389/fvets.2021.675804

Bibliografisk träff 2021-01-12

Wound formation, wound size, and progression of wound healing after intratumoral treatment of mast cell tumors in dogs with tigilanol tiglate.

Reddell P, De Ridder TR, Morton JM, Jones PD, Campbell JE, Brown G, Johannes CM, Schmidt PF, Gordon V.

J Vet Intern Med · randomized controlled trial, veterinary; research-article; journal article · DOI 10.1111/jvim.16009

Bibliografisk träff 2021-01-08

Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes.

Cullen JK, Boyle GM, Yap PY, Elmlinger S, Simmons JL, Broit N, Johns J, Ferguson B, Maslovskaya LA, Savchenko AI, Mirzayans PM, Porzelle A, Bernhardt PV, Gordon VA, Reddell PW, Pagani A, Appendino G, Parsons PG, Williams CM.

Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41598-020-80397-9

Bibliografisk träff 2020-12-22

Recurrence-free interval 12 months after local treatment of mast cell tumors in dogs using intratumoral injection of tigilanol tiglate.

Jones PD, Campbell JE, Brown G, Johannes CM, Reddell P.

J Vet Intern Med · randomized controlled trial, veterinary; research-article; journal article · DOI 10.1111/jvim.16018

Bibliografisk träff 2020-12-09

The allylic oxidation of tigliane esters.

Amin HIM, Maioli C, Chianese G, Appendino G, Gaeta S, Taglialatela-Scafati O.

Fitoterapia · journal article · DOI 10.1016/j.fitote.2020.104802

Bibliografisk träff 2020-09-09

Use of the Intratumoural Anticancer Drug Tigilanol Tiglate in Two Horses.

De Ridder T, Ruppin M, Wheeless M, Williams S, Reddell P.

Front Vet Sci · research-article; journal article · DOI 10.3389/fvets.2020.00639

Bibliografisk träff 2020-07-10

Transcriptome analysis of the medicinally significant plant Fontainea picrosperma (Euphorbiaceae) reveals conserved biosynthetic pathways.

Mitu SA, Cummins SF, Reddell PW, Ogbourne SM.

Fitoterapia · journal article · DOI 10.1016/j.fitote.2020.104680

Bibliografisk träff 2020-06-16

Randomized controlled clinical study evaluating the efficacy and safety of intratumoral treatment of canine mast cell tumors with tigilanol tiglate (EBC-46).

De Ridder TR, Campbell JE, Burke-Schwarz C, Clegg D, Elliot EL, Geller S, Kozak W, Pittenger ST, Pruitt JB, Riehl J, White J, Wiest ML, Johannes CM, Morton J, Jones PD, Schmidt PF, Gordon V, Reddell P.

J Vet Intern Med · randomized controlled trial, veterinary; research-article; journal article · DOI 10.1111/jvim.15806

Bibliografisk träff 2020-05-22

Novel epoxy-tiglianes stimulate skin keratinocyte wound healing responses and re-epithelialization via protein kinase C activation.

Moses RL, Boyle GM, Howard-Jones RA, Errington RJ, Johns JP, Gordon V, Reddell P, Steadman R, Moseley R.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2020.114048

Bibliografisk träff 2019-12-03

Phase I dose-escalation study to determine the safety, tolerability, preliminary efficacy and pharmacokinetics of an intratumoral injection of tigilanol tiglate (EBC-46).

Panizza BJ, de Souza P, Cooper A, Roohullah A, Karapetis CS, Lickliter JD.

EBioMedicine · research-article; multicenter study; clinical trial, phase i; journal article · DOI 10.1016/j.ebiom.2019.11.037

Bibliografisk träff 2019-04-09

Dose Characterization of the Investigational Anticancer Drug Tigilanol Tiglate (EBC-46) in the Local Treatment of Canine Mast Cell Tumors.

Miller J, Campbell J, Blum A, Reddell P, Gordon V, Schmidt P, Lowden S.

Front Vet Sci · research-article; journal article · DOI 10.3389/fvets.2019.00106

Bibliografisk träff 2018-04-18

Optimising intratumoral treatment of head and neck squamous cell carcinoma models with the diterpene ester Tigilanol tiglate.

Barnett CME, Broit N, Yap PY, Cullen JK, Parsons PG, Panizza BJ, Boyle GM.

Invest New Drugs · research support, non-u.s. gov't; journal article · DOI 10.1007/s10637-018-0604-y

Bibliografisk träff 2017-11-10

Progressive cutaneous viral pigmented plaques in three Hungarian Vizslas and the response of lesions to topical tigilanol tiglate gel.

Hansen N, Nicholas N, Pack G, Mackie JT, Shipstone M, Munday JS, Reddell P, Orbell G, Malik R.

Vet Med Sci · journal article; case-report · DOI 10.1002/vms3.85

Bibliografisk träff 2014-10-01

Intra-lesional injection of the novel PKC activator EBC-46 rapidly ablates tumors in mouse models.

Boyle GM, D'Souza MM, Pierce CJ, Adams RA, Cantor AS, Johns JP, Maslovskaya L, Gordon VA, Reddell PW, Parsons PG.

PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0108887