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Publikationer i urvalet

10 träffar

Bibliografisk träff 2023-02-02

Arginase 1 is a key driver of immune suppression in pancreatic cancer.

Menjivar RE, Nwosu ZC, Du W, Donahue KL, Hong HS, Espinoza C, Brown K, Velez-Delgado A, Yan W, Lima F, Bischoff A, Kadiyala P, Salas-Escabillas D, Crawford HC, Bednar F, Carpenter E, Zhang Y, Halbrook CJ, Lyssiotis CA, Pasca di Magliano M.

Elife · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.7554/elife.80721

Bibliografisk träff 2023-01-25

Radiation-induced circulating myeloid-derived suppressor cells induce systemic lymphopenia after chemoradiotherapy in patients with glioblastoma.

Ghosh S, Huang J, Inkman M, Zhang J, Thotala S, Tikhonova E, Miheecheva N, Frenkel F, Ataullakhanov R, Wang X, DeNardo D, Hallahan D, Thotala D.

Sci Transl Med · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1126/scitranslmed.abn6758

Bibliografisk träff 2022-09-08

Preclinical evidence of a direct pro-survival role of arginine deprivation in multiple myeloma.

Trudu M, Oliva L, Orfanelli U, Romano A, Di Raimondo F, Sanvito F, Ponzoni M, Cenci S.

Front Oncol · research-article; journal article · DOI 10.3389/fonc.2022.968208

Bibliografisk träff 2022-06-24

Muscarinic acetylcholine receptors regulate inflammatory responses through arginases 1/2 in zebrafish.

Chen AQ, He SM, Lv SJ, Qiu CZ, Zhou R, Zhang L, Zhang SR, Zhang Z, Ren DL.

Biomed Pharmacother · journal article · DOI 10.1016/j.biopha.2022.113321

Bibliografisk träff 2021-07-19

Cytokine-Mediated Regulation of ARG1 in Macrophages and Its Impact on the Control of <i>Salmonella enterica</i> Serovar Typhimurium Infection.

Brigo N, Pfeifhofer-Obermair C, Tymoszuk P, Demetz E, Engl S, Barros-Pinkelnig M, Dichtl S, Fischer C, Valente De Souza L, Petzer V, von Raffay L, Hilbe R, Berger S, Seifert M, Schleicher U, Bogdan C, Weiss G.

Cells · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/cells10071823

Bibliografisk träff 2020-07-23

Boronic acid-based arginase inhibitors in cancer immunotherapy.

Borek B, Gajda T, Golebiowski A, Blaszczyk R.

Bioorg Med Chem · review; journal article · DOI 10.1016/j.bmc.2020.115658

Bibliografisk träff 2020-03-13

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors.

Blaszczyk R, Brzezinska J, Dymek B, Stanczak PS, Mazurkiewicz M, Olczak J, Nowicka J, Dzwonek K, Zagozdzon A, Golab J, Golebiowski A.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/acsmedchemlett.9b00508

Bibliografisk träff 2019-11-26

Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158.

Grobben Y, Uitdehaag JCM, Willemsen-Seegers N, Tabak WWA, de Man J, Buijsman RC, Zaman GJR.

J Struct Biol X · research-article; journal article · DOI 10.1016/j.yjsbx.2019.100014

Bibliografisk träff 2017-12-20

Small molecule immuno-oncology therapeutic agents.

Toogood PL.

Bioorg Med Chem Lett · review; journal article · DOI 10.1016/j.bmcl.2017.12.044

Bibliografisk träff 2017-12-19

Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.

Steggerda SM, Bennett MK, Chen J, Emberley E, Huang T, Janes JR, Li W, MacKinnon AL, Makkouk A, Marguier G, Murray PJ, Neou S, Pan A, Parlati F, Rodriguez MLM, Van de Velde LA, Wang T, Works M, Zhang J, Zhang W, Gross MI.

J Immunother Cancer · research-article; journal article · DOI 10.1186/s40425-017-0308-4