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Publikationer i urvalet

9 träffar

Bibliografisk träff 2023-07-10

Dissecting the Role of SMYD2 and Its Inhibitor (LLY-507) in the Treatment of Chemically Induced Non-Small Cell Lung Cancer (NSCLC) by Using Fe<sub>3</sub>O<sub>4</sub> Nanoparticles Drug Delivery System.

Munawwar A, Sajjad A, Rasul A, Sattar M, Jabeen F.

Pharmaceuticals (Basel) · research-article; journal article · DOI 10.3390/ph16070986

Bibliografisk träff 2023-07-07

Pharmacological inhibition of SMYD2 protects against cisplatin-induced renal fibrosis and inflammation.

Chen M, Zuo S, Chen S, Li X, Zhang T, Yang D, Zou X, Yang Y, Long H, Peng R, Yuan H, Guo B, Liu L.

J Pharmacol Sci · journal article · DOI 10.1016/j.jphs.2023.07.003

Bibliografisk träff 2022-10-21

Histone methyltransferase Smyd2 drives adipogenesis via regulating STAT3 phosphorylation.

Su H, Meng C, Xu J, Su Z, Xiao C, Yang D.

Cell Death Dis · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41419-022-05321-7

Bibliografisk träff 2021-09-12

Novel insights into SMYD2 and SMYD3 inhibitors: from potential anti-tumoural therapy to a variety of new applications.

Rubio-Tomás T.

Mol Biol Rep · review; journal article · DOI 10.1007/s11033-021-06701-6

Bibliografisk träff 2021-01-06

Two-step generation of mesenchymal stem/stromal cells from human pluripotent stem cells with reinforced efficacy upon osteoarthritis rabbits by HA hydrogel.

Zhang L, Wei Y, Chi Y, Liu D, Yang S, Han Z, Li Z.

Cell Biosci · research-article; journal article · DOI 10.1186/s13578-020-00516-x

Bibliografisk träff 2020-10-02

Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors.

Zhang B, Liao L, Wu F, Zhang F, Sun Z, Chen H, Luo C.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2020.127598

Bibliografisk träff 2019-11-15

The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.

Whatley KCL, Padalino G, Whiteland H, Geyer KK, Hulme BJ, Chalmers IW, Forde-Thomas J, Ferla S, Brancale A, Hoffmann KF.

PLoS Negl Trop Dis · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pntd.0007693

Bibliografisk träff 2019-04-04

Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas.

Kukita A, Sone K, Oda K, Hamamoto R, Kaneko S, Komatsu M, Wada M, Honjoh H, Kawata Y, Kojima M, Oki S, Sato M, Asada K, Taguchi A, Miyasaka A, Tanikawa M, Nagasaka K, Matsumoto Y, Wada-Hiraike O, Osuga Y, Fujii T.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2019.03.155

Bibliografisk träff 2015-03-30

LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.

Nguyen H, Allali-Hassani A, Antonysamy S, Chang S, Chen LH, Curtis C, Emtage S, Fan L, Gheyi T, Li F, Liu S, Martin JR, Mendel D, Olsen JB, Pelletier L, Shatseva T, Wu S, Zhang FF, Arrowsmith CH, Brown PJ, Campbell RM, Garcia BA, Barsyte-Lovejoy D, Mader M, Vedadi M.

J Biol Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m114.626861