Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer.
Viana P, Hamar P.
Biochim Biophys Acta Rev Cancer · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.bbcan.2023.189069 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
23 träffarHeat shock factor 1 is a promising therapeutic target against adult T-cell leukemia.
Ishikawa C, Mori N.
Med Oncol · journal article · DOI 10.1007/s12032-023-02042-5A novel role of lactate: Promotion of Akt-dependent elongation of microglial process.
Hong H, Su J, Zhang Y, Xu G, Huang C, Bao G, Cui Z.
Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2023.110136HSF1 activates the FOXO3a-ΔNp63α-CDK4 axis to promote head and neck squamous cell carcinoma cell proliferation and tumour growth.
Wang Y, Zhu Q, Guo S, Ao J, Zhang W, Fei J, Yu S, Niu M, Zhang Y, Sherman MY, Xiao ZJ, Yi Y.
FEBS Lett · research support, non-u.s. gov't; journal article · DOI 10.1002/1873-3468.14588Dual inhibition of HSF1 and DYRK2 impedes cancer progression.
Tandon V, Moreno R, Allmeroth K, Quinn J, Wiley SE, Nicely LG, Denzel MS, Edwards J, de la Vega L, Banerjee S.
Biosci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1042/bsr20222102HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5-WDR5-dependent transcriptional program.
Huang M, Dong W, Xie R, Wu J, Su Q, Li W, Yao K, Chen Y, Zhou Q, Zhang Q, Li W, Cheng L, Peng S, Chen S, Huang J, Chen X, Lin T.
Cancer Commun (Lond) · research support, non-u.s. gov't; research-article; journal article · DOI 10.1002/cac2.12284KRIBB11: A Promising Drug that Promotes Microglial Process Elongation and Suppresses Neuroinflammation.
Su J, Dou Z, Hong H, Xu F, Lu X, Lu Q, Ye T, Huang C.
Front Pharmacol · research-article; journal article · DOI 10.3389/fphar.2022.857081Rational Design and Synthesis of HSF1-PROTACs for Anticancer Drug Development.
Sharma C, Choi MA, Song Y, Seo YH.
Molecules · research-article; journal article · DOI 10.3390/molecules27051655Trimetazidine enhances myocardial angiogenesis in pressure overload-induced cardiac hypertrophy mice through directly activating Akt and promoting the binding of HSF1 to VEGF-A promoter.
Shu HY, Peng YZ, Hang WJ, Zhang M, Shen L, Wang DW, Zhou N.
Acta Pharmacol Sin · research-article; journal article · DOI 10.1038/s41401-022-00877-8Heat shock factor 1 suppression induces spindle abnormalities and sensitizes cells to antimitotic drugs.
Kuo HH, Su ZR, Chuang JY, Yih LH.
Cell Div · research-article; journal article · DOI 10.1186/s13008-021-00075-8PLOD1 acts as a tumor promoter in glioma via activation of the HSF1 signaling pathway.
Yuan B, Xu Y, Zheng S.
Mol Cell Biochem · journal article · DOI 10.1007/s11010-021-04289-wKRIBB11 Induces Apoptosis in A172 Glioblastoma Cells via MULE-Dependent Degradation of MCL-1.
Yoo K, Yun HH, Jung SY, Lee JH.
Molecules · research-article; journal article · DOI 10.3390/molecules26144165Targeting HSF1 as a Therapeutic Strategy for Multiple Mechanisms of EGFR Inhibitor Resistance in EGFR Mutant Non-Small-Cell Lung Cancer.
Lee S, Jung J, Lee YJ, Kim SK, Kim JA, Kim BK, Park KC, Kwon BM, Han DC.
Cancers (Basel) · research-article; journal article · DOI 10.3390/cancers13122987HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression.
Wang Y, Xiu J, Yang T, Ren C, Yu Z.
Reprod Biol Endocrinol · research-article; journal article · DOI 10.1186/s12958-021-00770-9Modulated Electro-Hyperthermia Induces a Prominent Local Stress Response and Growth Inhibition in Mouse Breast Cancer Isografts.
Schvarcz CA, Danics L, Krenács T, Viana P, Béres R, Vancsik T, Nagy Á, Gyenesei A, Kun J, Fonović M, Vidmar R, Benyó Z, Kaucsár T, Hamar P.
Cancers (Basel) · research-article; journal article · DOI 10.3390/cancers13071744Hop depletion reduces HSF1 levels and activity and coincides with reduced stress resilience.
Chakraborty A, Edkins AL.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2020.04.072HSF1 Regulates Mevalonate and Cholesterol Biosynthesis Pathways.
Kang H, Oh T, Bahk YY, Kim GH, Kan SY, Shin DH, Kim JH, Lim JH.
Cancers (Basel) · research-article; journal article · DOI 10.3390/cancers11091363Inhibition of Heat Shock Factor 1 Enhances Repressive Molecular Mechanisms on the POMC Promoter.
Ciato D, Li R, Monteserin Garcia JL, Papst L, D'Annunzio S, Hristov M, Tichomirowa MA, Belaya Z, Rozhinskaya L, Buchfelder M, Theodoropoulou M, Paez-Pereda M, Stalla GK.
Neuroendocrinology · research support, non-u.s. gov't; journal article · DOI 10.1159/000500200HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.
Fok JHL, Hedayat S, Zhang L, Aronson LI, Mirabella F, Pawlyn C, Bright MD, Wardell CP, Keats JJ, De Billy E, Rye CS, Chessum NEA, Jones K, Morgan GJ, Eccles SA, Workman P, Davies FE.
Clin Cancer Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1158/1078-0432.ccr-17-1594KRIBB11 accelerates Mcl-1 degradation through an HSF1-independent, Mule-dependent pathway in A549 non-small cell lung cancer cells.
Kang MJ, Yun HH, Lee JH.
Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2017.08.118Interference with the HSF1/HSP70/BAG3 Pathway Primes Glioma Cells to Matrix Detachment and BH3 Mimetic-Induced Apoptosis.
Antonietti P, Linder B, Hehlgans S, Mildenberger IC, Burger MC, Fulda S, Steinbach JP, Gessler F, Rödel F, Mittelbronn M, Kögel D.
Mol Cancer Ther · journal article · DOI 10.1158/1535-7163.mct-16-0262Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737.
Mani J, Antonietti P, Rakel S, Blaheta R, Bartsch G, Haferkamp A, Kögel D.
World J Urol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00345-015-1616-2KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter.
Yoon YJ, Kim JA, Shin KD, Shin DS, Han YM, Lee YJ, Lee JS, Kwon BM, Han DC.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m110.179440