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Publikationer i urvalet

15 träffar

Bibliografisk träff 2024-04-05

Mesenchymal stromal cell chondrogenesis under ALK1/2/3-specific BMP inhibition: a revision of the prohypertrophic signalling network concept.

Diederichs S, Dreher SI, Nüesch SA, Schmidt S, Merle C, Richter W.

Stem Cell Res Ther · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s13287-024-03710-7

Bibliografisk träff 2024-01-12

BMP9-ID1 Pathway Attenuates N<sup>6</sup>-Methyladenosine Levels of CyclinD1 to Promote Cell Proliferation in Hepatocellular Carcinoma.

Chen H, Zhang M, Li J, Liu M, Cao D, Li YY, Yamashita T, Nio K, Tang H.

Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms25020981

Bibliografisk träff 2023-04-28

Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy.

Darwish NHE, Hussein KA, Elmasry K, Ibrahim AS, Humble J, Moustafa M, Awadalla F, Al-Shabrawey M.

Cells · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.3390/cells12091279

Bibliografisk träff 2022-04-26

Probiotics Enhance Bone Growth and Rescue BMP Inhibition: New Transgenic Zebrafish Lines to Study Bone Health.

Sojan JM, Raman R, Muller M, Carnevali O, Renn J.

Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms23094748

Bibliografisk träff 2022-01-27

BMP9-ID1 Signaling Activates HIF-1α and VEGFA Expression to Promote Tumor Angiogenesis in Hepatocellular Carcinoma.

Chen H, Nio K, Tang H, Yamashita T, Okada H, Li Y, Doan PTB, Li R, Lv J, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S.

Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms23031475

Bibliografisk träff 2021-05-02

BMP9-ID1 signaling promotes EpCAM-positive cancer stem cell properties in hepatocellular carcinoma.

Chen H, Nio K, Yamashita T, Okada H, Li R, Suda T, Li Y, Doan PTB, Seki A, Nakagawa H, Toyama T, Terashima T, Iida N, Shimakami T, Takatori H, Kawaguchi K, Sakai Y, Yamashita T, Mizukoshi E, Honda M, Kaneko S.

Mol Oncol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1002/1878-0261.12963

Bibliografisk träff 2020-12-24

BMP Ligand Trap ALK3-Fc Attenuates Osteogenesis and Heterotopic Ossification in Blast-Related Lower Extremity Trauma.

Strong AL, Spreadborough PJ, Dey D, Yang P, Li S, Lee A, Haskins RM, Grimm PD, Kumar R, Bradley MJ, Yu PB, Levi B, Davis TA.

Stem Cells Dev · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1089/scd.2020.0162

Bibliografisk träff 2019-10-16

Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway.

Omi M, Kaartinen V, Mishina Y.

J Biol Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.ra119.009521

Bibliografisk träff 2019-03-04

ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.

Hoeman CM, Cordero FJ, Hu G, Misuraca K, Romero MM, Cardona HJ, Nazarian J, Hashizume R, McLendon R, Yu P, Procissi D, Gadd S, Becher OJ.

Nat Commun · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41467-019-08823-9

Bibliografisk träff 2017-09-12

Structural basis for the potent and selective binding of LDN-212854 to the BMP receptor kinase ALK2.

Williams E, Bullock AN.

Bone · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1016/j.bone.2017.09.004

Bibliografisk träff 2017-07-15

Strategic Targeting of Multiple BMP Receptors Prevents Trauma-Induced Heterotopic Ossification.

Agarwal S, Loder SJ, Breuler C, Li J, Cholok D, Brownley C, Peterson J, Hsieh HH, Drake J, Ranganathan K, Niknafs YS, Xiao W, Li S, Kumar R, Tompkins R, Longaker MT, Davis TA, Yu PB, Mishina Y, Levi B.

Mol Ther · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.ymthe.2017.01.008

Bibliografisk träff 2017-05-01

Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK.

Ying Y, Ueta T, Jiang S, Lin H, Wang Y, Vavvas D, Wen R, Chen YG, Luo Z.

Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.15825

Bibliografisk träff 2016-11-01

Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification.

Dey D, Bagarova J, Hatsell SJ, Armstrong KA, Huang L, Ermann J, Vonner AJ, Shen Y, Mohedas AH, Lee A, Eekhoff EM, van Schie A, Demay MB, Keller C, Wagers AJ, Economides AN, Yu PB.

Sci Transl Med · research-article; journal article · DOI 10.1126/scitranslmed.aaf1090

Bibliografisk träff 2015-11-26

Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva.

Cai J, Orlova VV, Cai X, Eekhoff EMW, Zhang K, Pei D, Pan G, Mummery CL, Ten Dijke P.

Stem Cell Reports · brief-report; research support, non-u.s. gov't; journal article · DOI 10.1016/j.stemcr.2015.10.020

Bibliografisk träff 2013-04-30

Development of an ALK2-biased BMP type I receptor kinase inhibitor.

Mohedas AH, Xing X, Armstrong KA, Bullock AN, Cuny GD, Yu PB.

ACS Chem Biol · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/cb300655w