NSC689857, an inhibitor of Skp2, produces antidepressant-like effects in mice.
Liu Q, Cheng L, Li F, Zhu H, Lu X, Huang C, Yuan X.
Behav Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1097/fbp.0000000000000773 PUBLIKATIONSREGISTRET
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11 träffarSKP2 promotes the metastasis of pancreatic ductal adenocarcinoma by suppressing TRIM21-mediated PSPC1 degradation.
Yuan J, Zhu Z, Zhang P, Ashrafizadeh M, Abd El-Aty AM, Hacımüftüoğlu A, Linnebacher CS, Linnebacher M, Sethi G, Gong P, Zhang X.
Cancer Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.canlet.2024.216733Small-molecule compounds inhibiting S-phase kinase-associated protein 2: A review.
Jing J, Rui L, Junyuan S, Jinfeng Y, Zhihao H, Weiguo L, Zhenyu J.
Front Pharmacol · review-article; review; journal article · DOI 10.3389/fphar.2023.1122008SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals.
Gassen NC, Papies J, Bajaj T, Emanuel J, Dethloff F, Chua RL, Trimpert J, Heinemann N, Niemeyer C, Weege F, Hönzke K, Aschman T, Heinz DE, Weckmann K, Ebert T, Zellner A, Lennarz M, Wyler E, Schroeder S, Richter A, Niemeyer D, Hoffmann K, Meyer TF, Heppner FL, Corman VM, Landthaler M, Hocke AC, Morkel M, Osterrieder N, Conrad C, Eils R, Radbruch H, Giavalisco P, Drosten C, Müller MA.
Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-021-24007-wEmerging Roles of SKP2 in Cancer Drug Resistance.
Wu T, Gu X, Cui H.
Cells · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.3390/cells10051147Identification of the antidepressive properties of C1, a specific inhibitor of Skp2, in mice.
Li F, Huang C, Lu X, Xiang H, Wang D, Chen Z, Chen J, He H, Yuan X.
Behav Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1097/fbp.0000000000000604SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination.
Li C, Du L, Ren Y, Liu X, Jiao Q, Cui D, Wen M, Wang C, Wei G, Wang Y, Ji A, Wang Q.
J Exp Clin Cancer Res · research-article; journal article · DOI 10.1186/s13046-019-1069-3SMIP004: A compound with antidepressant-like activities in mouse models.
Wang D, Xu X, Wu Y, Lin Y, Gao M, Hu P, Chen D, Lu X, Chen Z, Wang H, Huang C.
Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2018.11.039Inhibition of Skp2 sensitizes lung cancer cells to paclitaxel.
Huang T, Yang L, Wang G, Ding G, Peng B, Wen Y, Wang Z.
Onco Targets Ther · research-article; journal article · DOI 10.2147/ott.s125789Small molecule-induced mitochondrial disruption directs prostate cancer inhibition via UPR signaling.
Rico-Bautista E, Zhu W, Kitada S, Ganapathy S, Lau E, Krajewski S, Ramirez J, Bush JA, Yuan Z, Wolf DA.
Oncotarget · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.18632/oncotarget.1130Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells.
Rico-Bautista E, Yang CC, Lu L, Roth GP, Wolf DA.
BMC Biol · research support, non-u.s. gov't; research-article; validation study; evaluation study; journal article; research support, n.i.h., extramural · DOI 10.1186/1741-7007-8-153