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Publikationer i urvalet

14 träffar

Bibliografisk träff 2023-10-20

Imidazo[2,1-b]thiazole based indoleamine-2,3-dioxygenase 1 (IDO1) inhibitor: Structure based design, synthesis, bio-evaluation and docking studies.

Singh R, Kumar R, Roy A, Behera PM, Atri AK, Kumar K, Manna D, Dixit A, Patil MT, Mankamna Kumari R, Nimesh S, Salunke DB.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2023.129532

Bibliografisk träff 2022-08-06

4,6-Disubstituted-1H-Indazole-4-Amine derivatives with immune-chemotherapy effect and in vivo antitumor activity.

Huo C, Luo Z, Ning X, Kang X, Yan Q, Guo Y, Li G, Wang Z, Li Y, Qian S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2022.114625

Bibliografisk träff 2022-06-08

Dual-target inhibitors of indoleamine 2, 3 dioxygenase 1 (Ido1): A promising direction in cancer immunotherapy.

Zhang Y, Hu Z, Zhang J, Ren C, Wang Y.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2022.114524

Bibliografisk träff 2021-11-02

Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors and PROTAC-based degraders for cancer therapy.

Tang K, Wang B, Yu B, Liu HM.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2021.113967

Bibliografisk träff 2021-06-10

X-ray Structure-Guided Discovery of a Potent, Orally Bioavailable, Dual Human Indoleamine/Tryptophan 2,3-Dioxygenase (hIDO/hTDO) Inhibitor That Shows Activity in a Mouse Model of Parkinson's Disease.

Ning XL, Li YZ, Huo C, Deng J, Gao C, Zhu KR, Wang M, Wu YX, Yu JL, Ren YL, Luo ZY, Li G, Chen Y, Wang SY, Peng C, Yang LL, Wang ZY, Wu Y, Qian S, Li GB.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c00303

Bibliografisk träff 2020-11-20

Development of Indoleamine 2,3-Dioxygenase 1 Inhibitors for Cancer Therapy and Beyond: A Recent Perspective.

Feng X, Liao D, Liu D, Ping A, Li Z, Bian J.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.0c00925

Bibliografisk träff 2020-05-01

Discovery of indoximod prodrugs and characterization of clinical candidate NLG802.

Kumar S, Jaipuri FA, Waldo JP, Potturi H, Marcinowicz A, Adams J, Van Allen C, Zhuang H, Vahanian N, Link C, Brincks EL, Mautino MR.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112373

Bibliografisk träff 2020-01-09

Dual-functional conjugates improving cancer immunochemotherapy by inhibiting tubulin polymerization and indoleamine-2,3-dioxygenase.

Hua S, Chen F, Wang X, Gou S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112041

Bibliografisk träff 2018-08-13

Recent advances in small molecule based cancer immunotherapy.

Cheng B, Yuan WE, Su J, Liu Y, Chen J.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2018.08.028

Bibliografisk träff 2018-03-01

Discovery of indoleamine 2,3-dioxygenase inhibitors using machine learning based virtual screening.

Zhang H, Liu W, Liu Z, Ju Y, Xu M, Zhang Y, Wu X, Gu Q, Wang Z, Xu J.

Medchemcomm · research-article; journal article · DOI 10.1039/c7md00642j

Bibliografisk träff 2017-12-01

Recent discovery of indoleamine-2,3-dioxygenase 1 inhibitors targeting cancer immunotherapy.

Weng T, Qiu X, Wang J, Li Z, Bian J.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2017.11.088

Bibliografisk träff 2017-05-10

Identification and preliminary structure-activity relationships of 1-Indanone derivatives as novel indoleamine-2,3-dioxygenase 1 (IDO1) inhibitors.

Gao D, Li Y.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2017.05.017

Bibliografisk träff 2016-07-09

Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors.

Li J, Li Y, Yang D, Hu N, Guo Z, Kuang C, Yang Q.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2016.07.013

Bibliografisk träff 2010-02-01

Rational design of indoleamine 2,3-dioxygenase inhibitors.

Röhrig UF, Awad L, Grosdidier A, Larrieu P, Stroobant V, Colau D, Cerundolo V, Simpson AJ, Vogel P, Van den Eynde BJ, Zoete V, Michielin O.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm9014718